Agent Name |
Benzyl chloride |
CAS Number |
100-44-7 |
Formula |
C7-H7-Cl |
Major Category |
Other Classes |
Synonyms |
Benzene, (chloromethyl)-; Benzile (cloruro di) [Italian]; Benzyl chloride; Benzylchlorid [German]; Benzylchloride; Benzyle (chlorure de) [French]; Chloromethylbenzene; Chlorophenylmethane; Chlorure de benzyle [French]; Toluene, alpha-chloro-; Tolyl chloride; alpha-Chlorotoluene; alpha-Chlortoluol [German; [ChemIDplus] UN1738 |
Category |
Halogenated Aromatics |
Description |
Colorless to slightly yellow liquid with a pungent, aromatic odor; [NIOSH] |
Sources/Uses |
Used in the manufacture of dyes, plasticizers, lubricants, pharmaceuticals, and other organic chemicals; [ACGIH] |
Comments |
A mucous membrane and respiratory irritant; [ACGIH] A lachrymator; [CHEMINFO] Corrosive to the eyes; Irritating to the respiratory tract and may cause pulmonary edema; May damage the liver and kidneys and cause CNS depression; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
1 ppm |
PEL (OSHA) |
1 ppm |
IDLH (NIOSH) |
10 ppm |
Excerpts from Documentation for IDLHs |
Human data: It has been reported that an exposure to 16 ppm for 1 minute is intolerable [Flury and Zernik 1931]. It has also been reported that 10 to 19 ppm immediately causes weeping and twitching of the eyelids [ILO 1971]. |
Vapor Pressure |
1.23 mm Hg |
Odor Threshold Low |
0.04 ppm |
Odor Threshold High |
0.04 ppm |
RD50 |
17 ppm |
Lethal Concentration |
LC50 (rats) = 150 ppm/2H |
Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.041 ppm); Flash point = 153 deg F; |
Half Life |
Whole body (animal studies): 2-3 days; [TDR, p. 177] |
Flammability (NFPA) |
2: high ambient temperature required |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Dermatotoxin |
Skin Burns |
Lacrimator |
Yes |
Neurotoxin |
Other CNS Neurotoxin |
Hepatotoxin |
Hepatotoxin, Secondary |
IARC Carcinogen |
Probable Carcinogen |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: BENZYL CHLORIDE
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