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Agent Name Benzyl chloride
CAS Number 100-44-7
Formula C7-H7-Cl
Major Category Other Classes
Synonyms Benzene, (chloromethyl)-; Benzile (cloruro di) [Italian]; Benzyl chloride; Benzylchlorid [German]; Benzylchloride; Benzyle (chlorure de) [French]; Chloromethylbenzene; Chlorophenylmethane; Chlorure de benzyle [French]; Toluene, alpha-chloro-; Tolyl chloride; alpha-Chlorotoluene; alpha-Chlortoluol [German; [ChemIDplus] UN1738
Category Halogenated Aromatics
Description Colorless to slightly yellow liquid with a pungent, aromatic odor; [NIOSH]
Sources/Uses Used in the manufacture of dyes, plasticizers, lubricants, pharmaceuticals, and other organic chemicals; [ACGIH]
Comments A mucous membrane and respiratory irritant; [ACGIH] A lachrymator; [CHEMINFO] Corrosive to the eyes; Irritating to the respiratory tract and may cause pulmonary edema; May damage the liver and kidneys and cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 1 ppm
PEL (OSHA) 1 ppm
IDLH (NIOSH) 10 ppm
Excerpts from Documentation for IDLHs Human data: It has been reported that an exposure to 16 ppm for 1 minute is intolerable [Flury and Zernik 1931]. It has also been reported that 10 to 19 ppm immediately causes weeping and twitching of the eyelids [ILO 1971].
Vapor Pressure 1.23 mm Hg
Odor Threshold Low 0.04 ppm
Odor Threshold High 0.04 ppm
RD50 17 ppm
Lethal Concentration LC50 (rats) = 150 ppm/2H
Explanatory Notes Detection odor threshold from AIHA (mean = 0.041 ppm); Flash point = 153 deg F;
Half Life Whole body (animal studies): 2-3 days; [TDR, p. 177]
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Toxic Pneumonitis Yes
Dermatotoxin Skin Burns
Lacrimator Yes
Neurotoxin Other CNS Neurotoxin
Hepatotoxin Hepatotoxin, Secondary
IARC Carcinogen Probable Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: BENZYL CHLORIDE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009