Compounds:   All: 79497   Active: 9505   Inactive: 70070
Substances:   All: 85477   Active: 10366   Inactive: 75111
Protein: 4 Links

Growth inhibition of yeast strains with defined genetic alterations is measured as a screen for potential anti-cancer activity. Selected strains with alterations in DNA damage repair or cell cycle control were exposed to compounds and growth inhibition was measured relative to vehicle treated controls. The strain used in this assay is bub3

These data are a subset of the data from the NCI yeast anticancer drug screen. Compounds are identified by the NCI NSC number. In the Seattle Project numbering system, the bub3 strain is SPY number 50779
Compounds with inhibition of growth(giprct) >= 70% were considered active. Activity score was based on increasing values of giprct.

TID	Name	Description	Type	Unit
	Outcome	The BioAssay activity outcome	String
	Score	The BioAssay activity ranking score	Integer
1	conc	concentration tested, unit: micromolar	Float	uM
2	giprct	Inhibiton of growth compared to untreated controls (%)	Float
3	nbrtest	Number of tests averaged for this data point	Integer
4	range	Range of values for this data point	Float