Licensable Technologies : Materials : Manufacturing & Fabrication

Gold Coated Nanoparticles for Biotechnology Applications

Abstract
A method for coating magnetic nanoparticles with a very thin layer of gold.  Because many biological markers and linkers have been adapted to attach to gold surfaces, a functional coating of gold allows nanoparticles of other materials to be used with the established markers and linkers.  Magnetic nanoparticles are of particular interest for in vivo imaging and treatment operations.

Application(s)

• Image enhancement in magnetic based diagnostics (such as MRI or other proprietary techniques)
• Cancer imaging and treatment

Advantages

• Avoids direct contact between biological tissue and the core nanoparticle material
• Permits a wide range of magnetic materials to be used in biological tissue
• Simple, rapid, and relatively inexpensive chemical process

IP Status: Available both Exclusively and Non Exclusively

Reference Number: 475

S Number: DOE reference no.(s): 100,503; 112,818

Patents & Applications:
United States National Patent Number 7226636 Issued on 06/05/2007

Posted: 06-25-2008

Contact
David Hadley
Technology Transfer Division
Los Alamos National Laboratory
P.O. Box 1663, MailStop C334
(505) 667-7539
dhadley@lanl.gov