Rectal Cancer Endpoints

11/20/2003

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Table of Contents

ASCO/FDA Public Workshop on Clinical Trials Endpoints in Colorectal Cancer

Evolution of Adjuvant Treatment

Proposed Rectal Cancer Endpoints

Local-Regional Failure

Local-Regional Failure Characteristics

Post-Op ChemoRT vs Surgery

Post-Op ChemoRT vs Single Modality

Short-Term Pre-Op Radiotherapy vs Surgery Alone

Pre-Op vs Post-Op Chemoradiation

German Trial – CAO/ARO/AIO-94

Pathologic Complete Response

Pathologic Assessment: # Lymph Nodes & Outcome

Future US Phase III Trials: Rectal Cancer

PPT Slide

Rectal Cancer Endpoints Neoadjuvant Therapy-Stage II/III Rectal Cancer

 

Home Page: http://www.fda.gov/cder/drug/cancer_endpoints/default.htm

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