Prostate Cancer Models(updated 10/15/03)
Welcome to the MMHCC Prostate Cancer Site. On this web site, you will find
a brief introduction to prostate cancer, including cancer incidence, diagnosis, treatment,
and modeling of the disease. The introductory section is followed by
several sections with more detailed information and discussion of specific topics
listed below:
Introduction
Adenocarcinoma of the prostate has become the most common cancer in American men and will be
responsible for an estimated 30,000 deaths in 2003, a mortality rate second only to lung cancer.
Despite the magnitude of the problem, rapid progress in prostate cancer research has been slow,
due, in part, to the scarcity of adequate animal model systems that reproduce the spectrum of
human prostatic disease. Therefore, the long term objective for the Mouse Models of Human Cancer
Consortium Prostate Group is to develop, characterize and disseminate credentialed transgenic and
germ-line mouse models for prostate cancer to facilitate direct characterization of the molecular
and cellular mechanisms governing transformation of the differentiating prostate in vivo and to
facilitate the development and pre-clinical evaluation of novel strategies for prevention,
detection and intervention.
More Important Information:
Age Adjusted Cancer Death Rates (Male)
New Cancer Cases and Deaths
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