NINDS Neuroscience Funding Announcements

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Understanding and Preventing Brain Tumor Dispersal (R21)
Release Date: March 7, 2006
Announcement Number: PAS-06-201
Application Receipt Date:
June 1, 2006
October 1, 2006
February 16, 2007
June 16, 2007   

Funding Contact: Jane Fountain, Ph.D.
Program Area: Neural Environment

Brief Description:
Many brain tumors are highly invasive and therefore extremely difficult to treat. Cells from the primary tumor often infiltrate into surrounding brain tissues, so that removal of the main tumor mass is not sufficient to prevent recurrence. The goal of thisProgram Announcement with set-aside funds (PAS) is to promote studies that: (1) identify the properties of brain tumor cells that cause them to migrate; (2) determine how interaction of tumor cells with normal brain elements affects migration; and (3) translate understanding of these parameters into interventions that target invading tumor cells. Interdisciplinary studies that apply new concepts and methodologies from developmental neuroscience, genomics, precursor cell biology and other related fields are particularly encouraged.

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