NINDS Neuroscience Funding Announcements

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Small Business Innovation Research to Improve the Chemistry and Targeted Delivery of RNAi Molecules (SBIR [R43/R44])
Release Date: October 18, 2005
Announcement Number: PA-06-003
Application Receipt Date:
December 1, 2005
April 1, 2006
August 1, 2006
December 1, 2006
April 5, 2007
August 5, 2007
December 5, 2007   

Funding Contact: Danilo Tagle, Ph.D.
Program Area: Neurogenetics

Brief Description:
This PA will focus on techniques and technologies leading to improved chemical synthesis and delivery of RNAi, particularly those incorporating chemical modifications that change the properties of the siRNA molecules to increase their stability and their ability to be delivered more efficiently to target cells without increasing their toxicity. This PA is intended to support innovative research in the field of RNAi synthesis and delivery to defined target sites, conducted by small business concerns (SBIR).

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