"NREPP becomes a leading national resource for contemporary and reliable information on the scientific basis and practicality of interventions to prevent and/or treat mental and substance use disorders."

• A major agency activity within SAMHSA's Science to Service initiative
• A decision support tool and valuable resource for state and community-based organizations seeking to identify and select interventions to meet their needs
• Not a list of approved programs and practices

• Applicant submits intervention materials during open submission process
• Program Review Manager determines if minimum requirements are met and assigns priority points
• Interventions meeting minimum requirements in priority areas sent to SAMHSA Centers for approval
• SAMHSA approved interventions assigned to Review Coordinator who works with the applicant to complete review materials

• Intervention materials and summary packets prepared by Review Coordinators sent to two doctoral-level scientific reviewers to rate Strength of Evidence and Readiness for Dissemination dimensions
• Intervention materials sent to two consumer/family and/or program implementation reviewers to rate Readiness for Dissemination
• Scores and descriptive information sent to applicants for review and consent to post on NREPP Web site
• Intervention descriptive summaries and review results uploaded to NREPP Web site

Strength of Evidence

• Research articles and published/unpublished evaluation reports
• Grant final reports
• Replication reports
• Implementation manuals
• Data collection manuals

Readiness for Dissemination

• Implementation guides, training manuals, presentations and curricula
• Quality assurance and monitoring protocols and procedures
• Data collection protocols for process and outcome measures
• Products and materials adapted for different age/cultural groups

Additional Documents / Narrative To Describe:

• Costs of implementation: Start-up and maintenance
• Proprietary components of intervention
• Implementation history of intervention
• Unintended or adverse effects of the intervention
• Contact information

Strength of Evidence Reviewers

• Doctoral-level researchers and practitioners with scientific evaluation knowledge and experience

• Implementation experts and practitioners with service delivery experience; service consumers and/or family members

1. Demonstrate one or more positive outcomes in mental health and/or substance abuse behavior among individuals, communities, or populations
2. Demonstrate intervention results have been published in a peer-reviewed publication or documented in a comprehensive evaluation report
3. Demonstrate materials such as manuals, process guides, and training guides that are available to the public to implement the intervention.

1. Stand-alone pharmacologic treatments (FDA reviews and approves these). NREPP reviews are limited to on-label use of FDA-approved pharmacotherapy interventions that are combined with one or more psychosocial treatments.
2. Stand-alone smoking cessation interventions. These are only appropriate for NREPP review when conducted as part of a program for treatment of alcohol or other drugs of abuse.

1 priority point — Research design
Experimental (e.g., randomized control study) or quasi-experimental (e.g., pre/post with comparison group, or interrupted time series) research design

1 priority point — Priority topic area
Primary outcome(s) of the submitted intervention is (are) in one or more of SAMHSA's Center-specific priority areas.

More information on NREPP is available through SAMHSA's Web site by clicking on "National Registry of Evidence-based Programs and Practices" on the SAMHSA home page at www.samhsa.gov.

Kevin D. Hennessy, Ph.D.
Science to Service Coordinator, SAMHSA
Phone: 240-276-2234
E-mail: kevin.hennessy@samhsa.hhs.gov