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Myelodysplastic/Myeloproliferative Diseases Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 08/01/2008



General Information About Myelodysplastic/Myeloproliferative Diseases






Chronic Myelomonocytic Leukemia






Juvenile Myelomonocytic Leukemia






Atypical Chronic Myelogenous Leukemia






Myelodysplastic/Myeloproliferative Disease, Unclassifiable






Stages of Myelodysplastic/Myeloproliferative Diseases






Treatment Option Overview






Treatment Options for Myelodysplastic/Myeloproliferative Diseases






To Learn More About Myelodysplastic/Myeloproliferative Diseases






Get More Information From NCI






Changes to This Summary (08/01/2008)






About PDQ



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Myelodysplastic/Myeloproliferative Disease, Unclassifiable

Key Points for This Section


Myelodysplastic/myeloproliferative disease, unclassifiable, is a disease that has features of both myelodysplastic and myeloproliferative diseases but is not chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, or atypical chronic myelogenous leukemia.

In myelodysplastic /myeloproliferative disease, unclassifiable (MDS/MPD-UC), the body tells too many blood stem cells to develop into red blood cells, white blood cells, or platelets. Some of these blood stem cells never become mature blood cells. These immature blood cells are called blasts. Over time, the abnormal blood cells and blasts in the bone marrow crowd out the healthy red blood cells, white blood cells, and platelets.

MDS/MPD-UC is a very rare disease. Because it is so rare, the factors that affect risk and prognosis are not known.

Possible signs of chronic myelomonocytic leukemia include fever, feeling very tired, and weight loss.

These and other symptoms may be caused by MDS/MPD-UC. Other conditions may cause the same symptoms. A doctor should be consulted if any of the following problems occur:

  • Fever or frequent infections.
  • Shortness of breath.
  • Feeling very tired and weak.
  • Pale skin.
  • Easy bruising or bleeding.
  • Petechiae (flat, pinpoint spots under the skin caused by bleeding).
  • Pain or a feeling of fullness below the ribs.

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