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Gestational Trophoblastic Tumors Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 12/05/2007
Prognostic Factors Based on the WHO Scoring System

Prognostic Factor  Score 
Age
<39 0
>39 1
Antecedent pregnancy
hydatidiform mole 0
abortion 1
term 2
Interval between end of antecedent pregnancy and start of chemotherapy
<4 mo 0
4–6 mo 1
7–12 mo 2
>12 mo 4
hCG (IU/mL)
<1000 0
1,000–10,000 1
10,000–100,000 2
>100,000 4
ABO groups (female × male)
O × A or A × O 1
B or AB 2
Largest tumor, including uterine
3–5 cm 1
>5 cm 2
Site of metastases
spleen, kidney 1
gastrointestinal tract or liver 2
brain 4
Number of metastases identified
1–4 1
4–8 2
>8 4
Prior chemotherapy
single drug 2
2 or more drugs 4


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