National Cancer Institute
U.S. National Institutes of Health | www.cancer.gov

NCI Home
Cancer Topics
Clinical Trials
Cancer Statistics
Research & Funding
News
About NCI
Islet Cell Tumors (Endocrine Pancreas) Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 10/31/2008
Endocrine Tumors of the Pancreas

Islet cells  Secreted active agent  Tumor and syndrome 
Alpha Glucagon Glucagonoma (diabetes, dermatitis)
Beta Insulin Insulinoma (hypoglycemia)
Delta Somatostatin Somatostatinoma (mild diabetes)
D Gastrin Gastrinoma (peptic ulcer disease)
A -> D Vasoactive Intestinal Peptide (VIP) and/or other undefined mediators WDHA (watery diarrhea, hypokalemia, achlorhydria)
serotonin (5-HT) Carcinoid
ACTH Cushing disease
MSH Hyperpigmentation
Interacinar cells Secreted active agent Tumor and syndrome
F Pancreatic polypeptide Multiple hormonal syndromes
EC 5-HT Carcinoid


A Service of the National Cancer Institute
Department of Health and Human Services National Institutes of Health USA.gov