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Brief Summary

GUIDELINE TITLE

Care of the patient with amblyopia.

BIBLIOGRAPHIC SOURCE(S)

  • American Optometric Association. Care of the patient with amblyopia. 2nd ed. St. Louis (MO): American Optometric Association; 1997. 57 p. (Optometric clinical practice guideline; no. 4). [177 references]

GUIDELINE STATUS

This is the current release of the guideline.

According to the guideline developer, this guideline has been reviewed on a biannual basis and is considered to be current as of 2004. This review process involves updated literature searches of electronic databases and expert panel review of new evidence that has emerged since the original publication date.

BRIEF SUMMARY CONTENT

 
RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

 Go to the Complete Summary

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

Summarized by the National Guideline Clearinghouse (NGC):

Diagnosis of Amblyopia

The evaluation of a patient with amblyopia may include, but is not limited to the following areas. These examination components are not intended to be all inclusive because professional judgment and the individual patient's symptoms and findings may have a significant impact on the nature, extent, and course of the services provided. Each component is described in greater detail in the guideline document.

Potential Components of the Diagnostic Evaluation for Amblyopia

  1. Patient History
  2. Visual acuity
  3. Refraction (noncycloplegic and cycloplegic)
  4. Monocular fixation
  5. Ocular motor deviation
  6. Sensorimotor fusion
  7. Accomodation
  8. Ocular motility
  9. Ocular health assessment and systemic health screening
  10. Supplemental testing
    1. Electrodiagnostic testing
    2. Additional differential diagnostic testing

Management of amblyopia

Treatment should be directed toward the two primary etiologies of amblyopia: form deprivation and binocular inhibition. Amblyopia therapy effectively restores normal or near-normal visual function by eliminating eccentric fixation and/or developing more extensive synaptic input to the visual cortex. It improves monocular deficits of visual acuity, monocular fixation, accommodation, and ocular motility. The final step in amblyopia therapy, if possible, is to develop normal binocular vision. The establishment of binocular vision eliminates or significantly reduces the underlying binocular inhibition in unilateral amblyopia, which increases the probability of maintaining visual acuity improvements.

The following treatment options are discussed in greater detail in the guideline document:

  • Optical correction
  • Occlusion
  • Active vision therapy

Management of deprivation amblyopia, isometropic amblyopia, anisometropic amblyopia, and strabismic amblyopia are discussed in greater detail in the guideline document.

The frequency and composition of evaluation and management visits for amblyopia are summarized in the following table:


Type of Patients

Evaluation Visits

Prognosis1

Treatment Options2

Frequency of FU visits

Estimated Total VT visits3

Composition of FU Evaluations

VA REF MF BS

Monocular Form
Deprivation
Amblyopia
1-2 Fair, (if diagnosed and treated during critical period)
  1. Surgery, optical correction
  2. Surgery, optical correction, visual stimulation
  1. Every 2-4 wks for 1 yr; every 6 mos thereafter
  2. Every 2-4 wks for 1 yr; every 6 mos thereafter
Each visit Each visit -------- Each visit
Binocular Form Deprivation Amblyopia 1-2 Fair, (if diagnosed and treated during critical period)
  1. Surgery, optical correction
  2. Surgery, optical correction, visual stimulation
  1. Every 2-4 wks for 1 yr; every 6 mos thereafter
  2. Every 2-4 wks for 1 yr; every 6 mos thereafter
Each visit Each visit -------- Each visit
Isometropic Refractive Amblyopia 1-2 Good
  1. Optical correction
  2. Optical correction, vision therapy
  1. Reevaluate in 4-6 wks;
  2. Reevaluate in 4-6 wks; 2-6 mos FU after VT
10-15 Each visit PRN PRN Each visit
Anisometropic
Refractive Amblyopia
1-2 Good
  1. Optical correction
  2. Optical correction occlusion (part-time)
  3. Optical correction occlusion (part-time) vision therapy
  1. Reevaluate in 4-6 wks; every 2-6 mos FU
  2. Reevaluate in 4-6 wks; every 2-4 wks FU
  3. Reevaluate in 4-6 wks; 2-6 mos FU after VT
15-25 Each visit PRN PRN Each visit
Strabismic Amblyopia (Central Fixation) 1-2 Good
  1. Optical correction, occlusion
  2. Optical correction, occlusion, vision therapy
  1. Re-evaluate in 4-6 wks; every 2-4 wks FU
  2. Re-evaluate in 4-6 wks; 2-6 mos FU after VT
15-25 Each visit PRN PRN Each visit
Strabismic Amblyopia (Eccentric Fixation) 1-2 Fair
  1. Optical correction, occlusion
  2. Optical correction, occlusion, vision therapy
  1. Re-evaluate in 4-6 wks; every 2-4 wks FU
  2. Re-evaluate in 4-6 wks; 2-6 mos FU after VT
25-35 Each visit PRN Each visit Each visit

1 General prognosis; prognosis is improved during critical sensitive period of development, but compliance and motivation afford improvements into adulthood.
2 Surgery is indicated in cases of congenital cataract and ptosis.
3 Estimated visits may vary based on co-existing conditions, patient compliance, etc.

VA = visual acuity, REF = refractive status, MF = monocular fixation, BS = binocular status, FU = follow-up visit, VT = vision therapy, PRN = as necessary

CLINICAL ALGORITHM(S)

An algorithm is provided for Optometric Management of the Patient with Amblyopia.

EVIDENCE SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

The type of supporting evidence is not specifically stated for each recommendation.

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

  • American Optometric Association. Care of the patient with amblyopia. 2nd ed. St. Louis (MO): American Optometric Association; 1997. 57 p. (Optometric clinical practice guideline; no. 4). [177 references]

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

1994 (revised 1998; reviewed 2004)

GUIDELINE DEVELOPER(S)

American Optometric Association - Professional Association

SOURCE(S) OF FUNDING

Funding was provided by the Vision Service Plan (Rancho Cordova, California) and its subsidiary Altair Eyewear (Rancho Cordova, California)

GUIDELINE COMMITTEE

American Optometric Association Consensus Panel on Care of the Patient with Amblyopia

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Members: Michael W. Rouse, O.D., M.S. (Principal Author); Jeffrey S. Cooper, O.D., M.S.; Susan A. Cotter, O.D.; Leonard J. Press, O.D.; Barry M. Tannen, O.D.

AOA Clinical Guidelines Coordinating Committee Members: John F. Amos, O.D., M.S. (Chair); Kerry L. Beebe, O.D.; Jerry Cavallerano, O.D., Ph.D.; John Lahr, O.D.; Richard Wallingford, Jr., O.D.

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

Not stated

GUIDELINE STATUS

This is the current release of the guideline.

According to the guideline developer, this guideline has been reviewed on a biannual basis and is considered to be current as of 2004. This review process involves updated literature searches of electronic databases and expert panel review of new evidence that has emerged since the original publication date.

GUIDELINE AVAILABILITY

Electronic copies: Available from the American Optometric Association Web site.

Print copies: Available from the American Optometric Association, 243 N. Lindbergh, Blvd., St. Louis, MO 63141-7811

AVAILABILITY OF COMPANION DOCUMENTS

None available

PATIENT RESOURCES

The following is available:

  • Answers to your questions about lazy eye. St. Louis, MO: American Optometric Association. (Patient information pamphet).

Print copies: Available from the American Optometric Association, 243 N. Lindbergh Blvd., St. Louis, MO 63141-7881; Web site, www.aoanet.org.

Please note: This patient information is intended to provide health professionals with information to share with their patients to help them better understand their health and their diagnosed disorders. By providing access to this patient information, it is not the intention of NGC to provide specific medical advice for particular patients. Rather we urge patients and their representatives to review this material and then to consult with a licensed health professional for evaluation of treatment options suitable for them as well as for diagnosis and answers to their personal medical questions. This patient information has been derived and prepared from a guideline for health care professionals included on NGC by the authors or publishers of that original guideline. The patient information is not reviewed by NGC to establish whether or not it accurately reflects the original guideline's content.

NGC STATUS

This summary was completed by ECRI on December 2, 1999. The information was verified by the guideline developer as of January 27, 2000.

COPYRIGHT STATEMENT

DISCLAIMER

NGC DISCLAIMER

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Readers with questions regarding guideline content are directed to contact the guideline developer.


 

 

   
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