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Complete Summary

GUIDELINE TITLE

Care of the patient with age-related macular degeneration.

BIBLIOGRAPHIC SOURCE(S)

  • American Optometric Association. Care of the patient with age-related macular degeneration. 2nd ed. St. Louis (MO): American Optometric Association; 1997. 47 p. (Optometric clinical practice guideline; no. 6). [73 references]

GUIDELINE STATUS

This is the current release of the guideline.

According to the guideline developer, this guideline has been reviewed on a biannual basis and is considered to be current. This review process involves updated literature searches of electronic databases and expert panel review of new evidence that has emerged since the original publication date.

COMPLETE SUMMARY CONTENT

 
SCOPE
 METHODOLOGY - including Rating Scheme and Cost Analysis
 RECOMMENDATIONS
 EVIDENCE SUPPORTING THE RECOMMENDATIONS
 BENEFITS/HARMS OF IMPLEMENTING THE GUIDELINE RECOMMENDATIONS
 QUALIFYING STATEMENTS
 IMPLEMENTATION OF THE GUIDELINE
 INSTITUTE OF MEDICINE (IOM) NATIONAL HEALTHCARE QUALITY REPORT CATEGORIES
 IDENTIFYING INFORMATION AND AVAILABILITY
 DISCLAIMER

SCOPE

DISEASE/CONDITION(S)

Age-related macular degeneration

GUIDELINE CATEGORY

Diagnosis
Evaluation
Management

CLINICAL SPECIALTY

Optometry

INTENDED USERS

Health Plans
Optometrists

GUIDELINE OBJECTIVE(S)

  • To identify ocular, personal, and environmental risk characteristics for age-related macular degeneration (AMD)
  • To accurately diagnose AMD
  • To develop a decision making strategy for management of patients at risk for severe vision loss from AMD
  • To provide information and resources for appropriate patient education in the area of vision rehabilitation
  • To propose a philosophy and rationale for management and prevention of AMD

TARGET POPULATION

Adults with age-related macular degeneration

INTERVENTIONS AND PRACTICES CONSIDERED

Diagnosis of age-related macular degeneration

  1. Patient history
  2. Ocular examination
    • Best corrected visual acuity, including near monocular visual acuity
    • Amsler grid testing
    • Sensorimotor examination
    • Refraction
    • Biomicroscopy
    • Tonometry
    • Stereoscopic fundus examination with pupillary dilation
  3. Supplemental testing
    • Macular function assessment (e.g., contrast sensitivity, photostress test)
    • Color vision
    • Central 10-degree computerized automated perimetry
    • Fundus photography (including the use of a red-free filter)
    • Scanning laser ophthalmoscope

Management of age-related macular degeneration

  1. Laser photocoagulation treatment
  2. Amsler gird self-assessment
  3. Patient education
  4. UVR protection
  5. Antioxidant supplementation
  6. Low vision consultation and evaluation
  7. Consultation and referral

MAJOR OUTCOMES CONSIDERED

Not stated

METHODOLOGY

METHODS USED TO COLLECT/SELECT EVIDENCE

Hand-searches of Published Literature (Primary Sources)
Searches of Electronic Databases

DESCRIPTION OF METHODS USED TO COLLECT/SELECT THE EVIDENCE

The guideline developer performed literature searches using the National Library of Medicine's Medline database and the VisionNet database.

NUMBER OF SOURCE DOCUMENTS

Not stated

METHODS USED TO ASSESS THE QUALITY AND STRENGTH OF THE EVIDENCE

Expert Consensus (Committee)

RATING SCHEME FOR THE STRENGTH OF THE EVIDENCE

Not stated

METHODS USED TO ANALYZE THE EVIDENCE

Review

DESCRIPTION OF THE METHODS USED TO ANALYZE THE EVIDENCE

Not applicable

METHODS USED TO FORMULATE THE RECOMMENDATIONS

Not stated

RATING SCHEME FOR THE STRENGTH OF THE RECOMMENDATIONS

Not applicable

COST ANALYSIS

A formal cost analysis was not performed and published cost analyses were not reviewed.

METHOD OF GUIDELINE VALIDATION

Internal Peer Review

DESCRIPTION OF METHOD OF GUIDELINE VALIDATION

The Reference Guide for Clinicians was reviewed by the American Optometric Association (AOA) Clinical Guidelines Coordinating Committee and approved by the AOA Board of Trustees.

RECOMMENDATIONS

MAJOR RECOMMENDATIONS

Summarized by the National Guideline Clearinghouse (NGC):

Diagnosis of Age-Related Macular Degeneration

The evaluation of patients with retinal changes suggestive of age-related macular degeneration (AMD) or patients with diagnosed AMD may include, but is not limited to the following areas:

  1. Patient history
  2. Ocular examination
    • Best corrected visual acuity, including near monocular visual acuity
    • Amsler grid testing
    • Sensorimotor examination
    • Refraction
    • Biomicroscopy
    • Tonometry
    • Stereoscopic fundus examination with pupillary dilation
  3. Supplemental testing
    • Macular function assessment (e.g., contrast sensitivity, photostress test)
    • Color vision
    • Central 10-degree computerized automated perimetry
    • Fundus photography (including the use of a red-free filter)
    • Scanning laser ophthalmoscope

These components of patient care are described in greater detail in the guideline document.

Management of Age-Related Macular Degeneration

The extent to which an optometrist can provide medical treatment for age-related macular degeneration may vary, depending on the state's scope of practice laws and regulations and the individual optometrist's certification. Treatment of the patient with AMD may require consultation with or referral to the patient's primary care physician, an ophthalmologist, or other health care practitioner for those services outside the optometrist's scope of practice.

Management of the patient with nonexudative AMD varies considerably from that of the patient diagnosed with exudative AMD, for whom immediate treatment is critical. Treatment options for patients with nonexudative AMD and exudative AMD are described in greater detail in the guideline document.

The frequency and composition of evaluation and management visits for age-related macular degeneration is summarized in the following table:

Frequency and Composition of Evaluation and Management Visits for Age-Related Macular Degeneration


Type of Patient Frequency of Examination Amsler Grid Stereo Fundus Biomicroscopy Central 10 degree Automated Visual Field (AVF) Fundus Photography Management Plan

Patient with two or more risk factors for AMD, over age 55 Annual examination Yes Yes Yes; baseline, repeat every 2 years Yes; baseline, repeat every 2 years or as necessary Patient education; Recommend UVR protection, antioxidant supplementation, home Amsler weekly
Patient with hard drusen and/or pigmentary degeneration 6 to 12 months depending on extent of atrophy Yes Yes Yes; repeat every 2 years Yes; repeat every 2 years Patient education; Recommend UVR protection, antioxidant supplementation, home Amsler twice each week
Patient with geographic atrophy, VA 20/20-20/70 6 to 12 months depending on extent of atrophy Every interim visit Every interim visit Every 1 to 2 years Yes; repeat every year Patient education; Recommend UVR protection, antioxidant supplementation, home Amsler every other day; Monitor for CNV
Patient at high risk with soft confluent drusen and granular pigmentary degeneration 4 to 6 months Every interim visit Every interim visit Annually Annually Patient education; Recommend UVR protection, antioxidant supplementation, home Amsler daily; Low vision consultation and evaluation
Patient with CNV within 2500 microns of center of FAZ every 2 to 3 months 2 weeks after FA laser photocoagulation; at 6 weeks, then after repeat FA Every interim visit Every interim visit Semiannually Semiannually Patient education; Recommend UVR protection, antioxidant supplementation, home Amsler daily; immediate consultation for signs of recurrent CNV; Low vision consultation and evaluation
Patient with disciform scar in both eyes 6 to 12 months Not necessary Every interim visit Annually; consider central 30º AVF, depending on central fixation Annually Review; Low vision consultation and evaluation

CLINICAL ALGORITHM(S)

An algorithm is provided for Optometric Management of the Patient with AMD.

EVIDENCE SUPPORTING THE RECOMMENDATIONS

TYPE OF EVIDENCE SUPPORTING THE RECOMMENDATIONS

The type of supporting evidence is not specifically stated for each recommendation.

BENEFITS/HARMS OF IMPLEMENTING THE GUIDELINE RECOMMENDATIONS

POTENTIAL BENEFITS

Until the means to prevent or cure age-related macular degeneration (AMD) are in place, optometrists need to understand the etiopathogenesis of the disease in order to reduce patient's risk for severe vision loss by early identification and timely referral for laser photocoagulation. Optometrists should educate and inform patients about the natural history of the retinal abnormalities associated with AMD. In certain cases useful vision can be maintained if the patient is informed and educated to seek care promptly. Improved patient understanding of AMD will promote compliance and in some cases may help preserve useful vision.

Subgroups Most Likely to Benefit:

Patients within the following groups at risk should be screened for signs and symptoms of age-related macular degeneration:

  • Persons over 60 years of age
  • Persons with hypertension or cardiovascular disease
  • Cigarette smokers
  • Persons with a first-degree family (sibling or maternal) history of vision loss from AMD regardless of age
  • Persons with aphakia or pre-1984 pseudophakia
  • Persons whose history indicates significant cumulative light exposure

POTENTIAL HARMS

Not stated

QUALIFYING STATEMENTS

QUALIFYING STATEMENTS

Clinicians should not rely on this Clinical Guideline alone for patient care and management. Please refer to the references and other sources listed in the original guideline for a more detailed analysis and discussion of research and patient care information.

IMPLEMENTATION OF THE GUIDELINE

DESCRIPTION OF IMPLEMENTATION STRATEGY

An implementation strategy was not provided.

IMPLEMENTATION TOOLS

Clinical Algorithm

For information about availability, see the "Availability of Companion Documents" and "Patient Resources" fields below.

INSTITUTE OF MEDICINE (IOM) NATIONAL HEALTHCARE QUALITY REPORT CATEGORIES

IOM CARE NEED

Getting Better
Living with Illness
Staying Healthy

IOM DOMAIN

Effectiveness
Patient-centeredness

IDENTIFYING INFORMATION AND AVAILABILITY

BIBLIOGRAPHIC SOURCE(S)

  • American Optometric Association. Care of the patient with age-related macular degeneration. 2nd ed. St. Louis (MO): American Optometric Association; 1997. 47 p. (Optometric clinical practice guideline; no. 6). [73 references]

ADAPTATION

Not applicable: The guideline was not adapted from another source.

DATE RELEASED

1994 (reviewed 2004)

GUIDELINE DEVELOPER(S)

American Optometric Association - Professional Association

SOURCE(S) OF FUNDING

Funding was provided by the Vision Service Plan (Rancho Cordova, California) and its subsidiary Altair Eyewear (Rancho Cordova, California)

GUIDELINE COMMITTEE

American Optometric Association Consensus Panel on Care of the Patient with Age-Related Macular Degeneration

COMPOSITION OF GROUP THAT AUTHORED THE GUIDELINE

Members: Anthony A. Cavallerano, O.D. (Principal Author); John P. Cummings, O.D.; Paul B. Freeman, O.D.; Randall T. Jose, O.D.; Leonard J. Oshinskie, O.D.; John W. Potter, O.D.

AOA Clinical Guidelines Coordinating Committee Members: John F. Amos, O.D., M.S., (Chair); Kerry L. Beebe, O.D.; Jerry Cavallerano, O.D., Ph.D.; John Lahr, O.D.; Richard Wallingford, Jr., O.D.

FINANCIAL DISCLOSURES/CONFLICTS OF INTEREST

Not stated

GUIDELINE STATUS

This is the current release of the guideline.

According to the guideline developer, this guideline has been reviewed on a biannual basis and is considered to be current. This review process involves updated literature searches of electronic databases and expert panel review of new evidence that has emerged since the original publication date.

GUIDELINE AVAILABILITY

Electronic copies: Available in Portable Document Format (PDF) from the American Optometric Association Web site.

Print copies: Available from the American Optometric Association, 243 N. Lindbergh, Blvd., St. Louis, MO 63141-7881

AVAILABILITY OF COMPANION DOCUMENTS

None available

PATIENT RESOURCES

None available

NGC STATUS

This summary was completed by ECRI on December 2, 1999. The information was verified by the guideline developer as of January 27, 2000.

COPYRIGHT STATEMENT

DISCLAIMER

NGC DISCLAIMER

The National Guideline Clearinghouse™ (NGC) does not develop, produce, approve, or endorse the guidelines represented on this site.

All guidelines summarized by NGC and hosted on our site are produced under the auspices of medical specialty societies, relevant professional associations, public or private organizations, other government agencies, health care organizations or plans, and similar entities.

Guidelines represented on the NGC Web site are submitted by guideline developers, and are screened solely to determine that they meet the NGC Inclusion Criteria which may be found at http://www.guideline.gov/about/inclusion.aspx .

NGC, AHRQ, and its contractor ECRI Institute make no warranties concerning the content or clinical efficacy or effectiveness of the clinical practice guidelines and related materials represented on this site. Moreover, the views and opinions of developers or authors of guidelines represented on this site do not necessarily state or reflect those of NGC, AHRQ, or its contractor ECRI Institute, and inclusion or hosting of guidelines in NGC may not be used for advertising or commercial endorsement purposes.

Readers with questions regarding guideline content are directed to contact the guideline developer.


 

 

   
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