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Streptococcus Disease, Invasive, Group A (Streptococcus
pyogenes)
1995 Case Definition
The 1995 case definition appearing on this page was later re-published in the 1997 MMWR Recommendations and
Reports titled Case Definitions for Infectious Conditions Under Public Health Surveillance [MMWR 1997;46(RR10)]
(available at http://www.cdc.gov/mmwr/preview/mmwrhtml/00047449.htm).
Thus, the 1995 and 1997 versions of this case definition are identical.
Clinical description
Invasive group A streptococcal infections may manifest
as any of several clinical syndromes, including pneumonia, bacteremia
in association with cutaneous infection (e.g., cellulitis, erysipelas,
or infection of a surgical or nonsurgical wound), deep soft-tissue
infection (e.g., myositis or necrotizing fasciitis), meningitis,
peritonitis, osteomyelitis, septic arthritis, postpartum sepsis
(i.e., puerperal fever), neonatal sepsis, and nonfocal bacteremia.
Laboratory criteria for diagnosis
-
Isolation of group A Streptococcus (Streptococcus
pyogenes) by culture from a normally sterile site
(e.g., blood or cerebrospinal fluid, or, less commonly,
joint, pleural, or pericardial fluid)
Case classification
Confirmed: a case
that is laboratory confirmed
Comment
See also Streptococcal
Toxic-Shock Syndrome.
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