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An infection of variable severity characterized by diarrhea and vomiting, primary septicemia, or wound infections. Asymptomatic infections may occur, and the organism may cause extraintestinal infections.
Isolation of Vibrio spp. other than toxigenic Vibrio cholerae O1 or O139 from a clinical specimen.*
Confirmed: A case that meets the laboratory criteria for diagnosis. Note that species identification and, if applicable, serotype designation (i.e., Vibrio cholerae non-O1/non-O139) should be reported.
Probable: A clinically-compatible symptomatic case that is epidemiologically linked to a confirmed case.
In addition to reporting through the National Notifiable Diseases Surveillance System (NNDSS), CDC requests that states collect information on the standard surveillance form for Cholera and Other Vibrio Illness Surveillance System (COVISS), available at: http://www.cdc.gov/foodborneoutbreaks/documents/cholera_vibrio_report.pdf. CDC intends to integrate the COVISS form into the National Electronic Diseases Surveillance System (NEDSS) in the future. Reporting sites should use the COVISS reporting form until the integration is complete and COVISS data can be transmitted to CDC. CDC requests that Vibrio cholerae and Vibrio parahaemolyticus isolates be referred to the Foodborne and Diarrheal Diseases Laboratory for characterization.
*Infections due to toxigenic Vibrio cholerae O1 or O139 are reportable as cholera (see current cholera case definition listed below).
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