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Streptococcus pneumoniae, Invasive Disease Non-Drug Resistant,
in Children Less Than 5 Years of Age (Invasive Pneumococcal Disease)
2007 Case Definition*
Clinical description
Streptococcus pneumoniae causes many clinical syndromes, depending on the site of
infection (e.g., acute otitis media, pneumonia, bacteremia, or meningitis). Starting in 2000,
a conjugate pneumococcal vaccine is recommended for prevention of pneumococcal disease in the
pediatric population.
Laboratory criteria for diagnosis
Isolation of S. pneumoniae from a normally sterile site (e.g., blood, cerebrospinal
fluid, or, less commonly, joint, pleural, or pericardial fluid)
Case classification
Confirmed: a clinically compatible case in a child less than five years of age caused by
laboratory-confirmed culture of S. pneumoniae from a normally sterile site
*Comment
The difference between this case definition and the previous case definition for this condition is the
inclusion of new case classifications for reporting purposes.
Case classifications for Drug Resistant Streptococcus pneumoniae (DRSP) and Invasive
Pneumococcal Disease (IPD) are modified as listed below:
- Isolates causing IPD from children less than five years of age for which antibacterial
susceptibilities are available and determined to be DRSP should be reported only as DRSP
(event code 11720).
- Isolates causing IPD from children less than five years of age which are susceptible, or for
which susceptibilities are not available should be reported ONLY as IPD in children less than
five years of age (event code 11717).
See also:
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