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Listeriosis (Listeria monocytogenes)
1999 Case Definition
The 1999 case definition appearing on this page was re-published in the 2003 CSTE position statement 2003-ID-01
(available at http://www.cste.org/PS/2003pdfs/2003finalpdf/03-ID-01Revised.pdf).
Thus, the 1999 and 2003 versions of this case definition are identical.
Clinical description
In adults, invasive disease caused by Listeria
monocytogenes manifests most commonly as meningitis or
bacteremia; infection during pregnancy may result in fetal
loss through miscarriage or stillbirth, or neonatal meningitis
or bacteremia. Other manifestations can also be observed.
Laboratory criteria for diagnosis
- Isolation of L. monocytogenes from a normally
sterile site (e.g., blood or cerebrospinal fluid [CSF] or, less
commonly, joint, pleural, or pericardial fluid)
- In the setting of miscarriage or stillbirth, isolation of L. monocytogenes from
placental or fetal tissue
Case classification
Confirmed: A clinically
compatible case that is laboratory-confirmed
Comment:
The usefulness of other laboratory methods such fluorescent
antibody testing or polymerase chain reaction to diagnose invasive
listeriosis has not been established.
See also:
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