11.45 - 12.10 Coffee Break
12.10 - 12.40
PLM1 - mycotoxins: OCCURRENCE IN FOOD AND BIOLOGICAL FLUIDS
J. D. Groopman - Johns Hopkins University (USA)
12.40 - 12.55
OM1 - Occurrence of fumonisins in foods in Germany
E. Usleber, C. Schlichtherle, M. Lakner and E. Martlbauer
12.55 - 13.10
OM2 - Evaluation of incidence of mycotoxins in Italy:
a comparison of three different methodological approaches
M. Miraglia, C. Brera, R. Onori, S. Corneli, M. Colatosti,
E. Cava, D. Ippoliti, M. Quaglia
13.10 - 13.20 - Discussion
13.20 - 14.30 - Lunch
16.00 - 16.15
OM3 - Occurrence of Fusarium mycotoxins in cereals in Russia
V. A. Tutelyan
16.15 - 16.30
OM4 - Ochratoxin A (OTA) in table wine and grape juice
B. Zimmerli, R. Dick
16.30 - 16.45
OM5 - Occurrence of aflatoxins B1, B2, G1, G2,
in imported goods in Greece during 1995
E. Apergi, J.P. Gardikis, V.J. Panagiotopoulou
16.45 - 17.00 - Discussion
17.00 - 17.20 - Coffee Break
17.20 - 17.35
OM6 - Occurrence of fumonisins in corn feedstuffs intended for
pig consumption in Bretain (France)
I. Dragoni, L. Piantanida, Y. Tyrilli, A. Visconti, M. Pascale
17.35 - 17.50
OM7 - Aflatoxin contamination in different types of peanut
kernels as defined by the Brazilian Official Classification
A. H.O. Stefanovitz, H. Fonseca, M.A.C. Domingues, E.M. Gloria
17.50 - 18.05
OM8 - Mycotoxin contamination of maize grown in Australia, the
Philippines and Vietnam
W.L. Bryden, G. Ravindran, M.T. Amba, R.J. Gill, L.W. Burgess
18.05 - 18.20 - Discussion
17.30 - 17.45
OM9 - The detection and measurement of aflatoxin B1 conjugates in humans in Natal, South Africa
M.F. Dutton, S. Myeni, D. Early, A. Chuturgoon, S. Bux
17.45 - 18.00
OM10 - Toxicity and occurrence of Fusarium species and mycotoxins
in late harvested and overwintered grain from Norway, 1993.
W. Langseth, Per-Erik Clasen, B. Kosiak, M. Torp, M. Gareis
18.00 - 18.10 - Discussion
20.00 - Welcome Drink
12.10 - 12.40
PLP1 - OCCURRENCE AND MONITORING OF HARMFUL ALGAE IN THE
MARINE ENVIRONMENT
O. Lindahl - Kristineberg Marine research Station (Sweden)
12.40 - 12.55
12.55 - 13.10
13.10 - 13.20 - Discussion
13.20 - 14.30 - Lunch
15.30 - 16.00
16.00 - 16.20 Coffee Break
16.20 - 16.35
16.35 - 16.50
16.50 - 17.00 - Discussion
17.00 - 17.20 - Coffee Break
20.00 - Welcome drink
Chairperson: H.P. van Egmond
K2 - Food safety : mycotoxins and phycotoxins in Perspective
T. Kuiper Goodman - Health CANADA (Canada)
9.45 - 10.15
10.15 - 10.45
10.45 - 11.00 - Coffee Break
11.00 - 11.15
11.15 - 11.30
11.30 - 11.45
11.45 - 12.00
12.00 - 12.20 - Discussion
12.20 - 12.35
12.35 - 12.50
12.50 - 13.05
13.05 - 13.20 Discussion
13.20 - 14.30 - Lunch
S1 - UK Sampling Plan for aflatoxins in food
S2 - The Dutch code of practice on peanuts in perspective
S3 - Control of mycotoxins in the US: Sampling Plans
S4 - The Development of Sampling Plans for the determination of
aflatoxins in animal feedingstuffs
S5 - Mycotoxins: Sampling Plans
S6 - Methods of sampling and analysis for mycotoxin detection in
food and feed
9.45-10.15
10.15 - 10.45
10.45 - 11.00 - Coffee Break
11.00 - 11.15
11.15 - 11.30
11.30 - 11.45
11.45 - 12.00 Discussion
12.00 - 12.15
12.15 - 12.30
12.45 - 13.20 - Discussion
13.20 - 14.30 - Lunch
15.30 - 16.00
16.00 - 16.15 - Coffee Break
16.15 - 16.30
16.30 - 16.45
16.45 - 17.00 - Discussion
9.00 - 9.30
9.30 - 9.45
9.45 - 10.00
10.00 - 10.15
10.15 - 10.30 Discussion
10.30 - 10.50 - Coffee Break
10.50 - 11.05
OM21 - HACCP and mycotoxins: what is the point of interaction?
11.05 - 11.20
11.20 - 11.35
11.35 - 11.50
11.50 - 12.05
12.05 - 12.30 Discussion
13.00 - 14.30 - Lunch
9.00 - 9.30
9.30 - 10.00
10.00 - 10.20 - Coffee Break
10.20 - 10.35
10.35 - 10.50
10.50 - 11.05
11.05- 11.20
11.20 - 11.40 Discussion
13.00 - 14.30 - Lunch
K3 - OVERVIEW of international mycotoxin and phycotoxin programs
A. E. Pohland - US Food and Drug Administration (USA)
9.45 - 10.15
10.15 - 10.30 - Coffee Break
10.30 - 10.45
10.45 - 11.00
11.00 - 11.15
11.15 - 11.30
11.30 - 11.50 Discussion
11.50 - 12.05
12.05 - 12.20
12.20 - 12.35
12.35- 12.50
12.50 - 13.10 Discussion
13.10 - 14.30 - Lunch
15.30 - 16.00
16.00 -16.20 - Coffee Break
16.20 - 16.35
16.35- 16.50
16.50 - 17.05
17.20 - 17.40 - discussion
Mycotoxin prevention and control: increasing awareness
Mycotoxin control in Latin America: Networking
Mycotoxin prevention and control: experience in Africa
Check sample programmes: experience in Latin America
Mycotoxin reference standards and kits
Training in Mycotoxin analysis
9.00- 9.20
9.20 - 10.00 - Two examples of typical projects supported by the SM&T:
9.20 - 9.40
9.40 - 10.00
10.00 - 10.30
10.30 - 11.00 Discussion
11.00 - 11.20 - Coffee Break
11.20 - 12.20
the Organising Committee is pleased to inform participants that apart
from Monday (8.30 - 10.00), it will also be possible to register on
Sunday afternoon from 4 pm until 7pm at the
ISTITUTO SUPERIORE DI SANITA - VIALE REGINA ELENA, 299.
We would advise registering on Sunday in order to avoid delays in
registration on Monday.
FOR FURTHER INFORMATION CONTACT:
SYMPOSIUM SECRETARIAT
Local Scientific Coordinators:
Dr. Marina Miraglia, Dr Carlo Brera
TRAVEL AGENCY
Servizi Internazionali S.r.l
Contact persons:
Mr Paolo Missiaja, Ms Stefania Mura
OP1 - Biotoxins on the Pacific Coast of Mexico
J.L. Ochoa, A. Cruz-Villacorta, E. Nunez-Vazquez, A. Sanchez-Paz,
A.P. Sierra-Beltran
OP2 - Immunochemical Survey of microcystins in environmental
water in various countries
Y. Ueno, S. Nagata, M. Sutajjit, D. Mebs, V. Vasconcelos14.30 - 15.30 Aula marotta: Poster Session
Aula Bovet
Chairpersons: J.M. Fremy and Y. UenoPlenary Lecture
PLP2 - OCCURRENCE OF AQUATIC BIOTOXINS IN SEAFOODS
T. Yasumoto - Tohoku University (Japan)Contributed Papers
OP3 - Mussel food selection and DSP contamination
L. Sidari, P. Nichetto, A. Tubaro, G. Honsell, R. Della Loggia
OP4 - Diarrhetic shellfish poisoning (DSP) toxins in
Dinophysis Fortii samples from the Adriatic sea
R. Draisci, L. Giannetti, L. Lucentini, P. Boria, R. Poletti,
L. Boni, E. Funari21.00 - A MUSICAL EVENING
Tuesday, 28 May
Live in the Aula Pocchiari
Closed circuit television in the Aula Bovet9.00 - 9.45 - KEYNOTE LECTURE
Mycotoxins and PhycotoxinsMYCOTOXINS
Aula Pocchiari
Chairperson: H.P. van EgmondPlenary Lectures
PLM3 - TOXICITY AND METABOLISM
J. L. Richard - USDA/Agriculture RESEARCH SERVICE (USA)
PLM4 - mycotoxins: MECHANISMS OF ACTION AT THE MOLECULAR LEVEL
J. Fink-Gremmels - Utrecht University (The Netherlands)Chairpersons: J. D. Groopman and T. Kuiper-Goodman
Contributed Papers
OM11 - Hepatocellular uptake of ochratoxin A is carrier-mediated
and occurs via the cloned organic anion transporting polypeptide OATP
M. Kontaxi, U. Eckhardt, B. Hagenbuch, B. Stieger, P.J. Meier,
E. Petzinger
om12 - Ochratoxin A occurrence in serum, placenta and funiculum
samples of Italian people
M. Miraglia, C. Brera, S. Corneli, M. Colatosti, E. Cava,
G. Montanino, E. Miraglia, F. Ventola, F. Ciaraldi, V. Miele
OM13 - Aflatoxin B1 in urine of humans with chronic B and C
hepatitis and cirrhosis in Mexico
M.T. Alvarez , M. Carvajal , M. Lisker-Melman
OM14 - Toxicokinetics of fumonisins B1, and B2:
comparative studies in rats and non-human primates
G.S. Shephard, P.G. Thiel, E.W. Sydenham, M.E. Savard, P.W. Bakkes
and R. Vleggaar
OM15 - Co-carcinogenicity study of fumonisin B1 and
N-methyl-N-benzylnitrosamine in relation to cancer of the
oesophagus in rats
C.P. Wild, L. Garren, M. Castegnaro, H. Ohgaki , D.Galendo,
J.D. Miller
OM16 - Improved method for sphinganine/sphingosine determination
in human urine as a biomarker of fumonisin exposure
M. Solfrizzo, G. Avantaggiato, A. Visconti
OM17 - Metabolic aspects of aflatoxin toxicity with particular
reference to the expression of potentially protective pathways
G.E. Neal, M.M. Manson14.30 - 15.30 Aula marotta:
Poster session
15.30-18.00 Aula Pocchiari
Sampling Workshop
Chairpersons: D. Park and R. Coker
J. Gilbert
W.J. de Koe
A.E. Pohland
R. COKER, M. NAGLER, P. DEFIZE, G. DERKSEN, J. HOOGLAND, H. BUCHHOLZ
H. ROSNER
C. CANET, J. PAAKKANENPHYCOTOXINS
Aula Bovet
Chairpersons: T. Yasumoto and L. TotiPlenary Lectures
PLP3 - toxicity and metabolism of phycotoxins
L. Edebo - Goteborg University (Sweden)
PLP4 - toxins produced by cyanobacteria
K. Sivonen - Helsinki University (Finland)Contributed Papers
OP5 - Implication of okadaic acid on DNA adduct formation and
erod activity
A. Pfohl-Leskowicz, V. Fessard, M. Lafaurie, Y. Gross , Puiseux-Dao
OP6 - Okadaic acid reorganizes the actin cytoskeleton in intestinal
cultured cells
C. Fiorentini, P. Matarrese, A. Fattorossi, G. Donelli
OP7 - Unexplained toxicity in molluscs found in the course of
phytoplankton monitoring
C. Marcaillou-Le Baut, Z. Amzil
OP8 - Cytotoxic activity of new diarrhoetic shellfish toxins
isolated from Italian mussels
R. Draisci, L. Lucentini, L. Giannetti, P. Boria, A. Stammati,
F. Nardelli, F. Zampaglioni, F. Zucco
OP9 - Biosensor application for the detection of okadaic acid in
mussels
Al. Stacchini, L. Cozzi, L. Toti, F. Botre, F. Mazzei
12.30 - 12.45
OP10 - Immunoaffinity chromatography as a tool for the analysis
of paralytic shellfish poisoning toxins
R. Dietrich, C. Burk, E. Usleber, E. Martlbauer, M.V. Laycock14.30 - 15.30 Aula marotta: Poster Session
Aula Bovet
Chairpersons: O. Lindahl and R. DraisciPlenary Lecture
PLP5 - management STRATEGIES for phycotoxin control
H. Ravn - IOC/UNESCO (France)Contributed Papers
OP11 - Identification of marine polyether compounds by tandem
mass spectrometry
H. Naoki. T. Fujita, M. Satake, T. Yasumoto
OP12 - Determination of microcystins in aqueous and cyanobacterial
samples using liquid micro-chromatography and capillary
electrophoresis
C. Rivasseau, N. Boua‹cha, M.C. Hennion, P. Sandra21.00 - A MUSICAL EVENING
Wednesday, 29 May
MYCOTOXINS
Aula Pocchiari
Chairpersons: C. Canet and J.M. FremyPlenary Lecture
PlM5 - mycotoxins: LIMITS AND EFFECTS ON TRADE
H.Rosner - Federal Institute for Health Protection of Consumers and
veterinary medicine (Germany)Contributed Papers
OM18 - Fusarium mycotoxin beauvericin: optimisation
of analytical methodology and natural occurrence in maize ears in Austria
R. Krska, R. Schuhmacher, M. Grasserbauer, M. Lemmens, P. Ruckenbauer, A. Alder, H. Lew
OM19 - Use of Polymerase Chain Reaction for the detection of Fusaria
M.L Niessen, R.F. Vogel
OM20 - Use of Capillary Electrophoresis for the separation of
ochratoxin A and its albumin conjugate in serum samples with
fluorescence detector
C. Desiderio, S. Fanali
C. Brera, M. Miraglia, R. Onori
OM22 - Proficiency testings for aflatoxin M1 monitoring programme:
a five year experience in France
S. Dragacci, J.M. Fremy
OM23 - Use of mass spectrometry to solve problems of analysis
concerning mycotoxins
F.Tateo, M. Miraglia, M. Bononi
OM24 - Rapid detection of ochratoxin A in wheat by flow-through
membrane-based enzyme immunoassay
S. De Saeger, C. Van Peteghem
OM25 - Development of metabolically competent in vitro models for
food safety evaluation
C.W. Lewis, J.E. Smith, J.G. Anderson Afternoon Session
Aula Pocchiari: Italian Open Forum on MycotoxinsPHYCOTOXINS
Aula Bovet
Chairpersons: H. Ravn and L. CrociPlenary lectures
PlP6 - Limits and effects on trade
M. L. Fernandez - health ministry - estacion maritima (Spain)
PLP7 - phycotoxins - a review of chemical and biological
methods
D. J. Hannah - Institute of Environmental Science AND Research
(New Zealand)Contributed Papers
OP13 - Photocatalytic decomposition of microcystins in water
S. Stockenstrom, D. de Villiers, W. J. Engelbrecht, G.S. Shephard,
E.W. Sydenham, P.G. Thiel, G.F.S. Wessels
OP14 - Removal of microcystins in lake water by water treatment process
G. Chen, Chuan-wei Chen, Shun-Zhang Yu, Y. Ueno
OP15 - A new constituent of diarrhetic shellfish toxins in
Irish mussels
K.J. James, E.P.Carmody, S.S. Kelly, R. Draisci, L. Lucentini,
L. Giannetti, A. Stacchini
OP16 - Sensitive HPLC-Fluorometric and HPLC-MS determination of
Diarrhetic Shellfish Poisoning (dsp) - toxins as 4-Bromomethyl-7-methoxycoumarin esters
J.L. Shen, C. Hummert, B. Luckas11.40 - 12.40 Aula Marotta : Poster Session
Thursday, 30 May
Live in the Aula Pocchiari
Closed circuit television in the Aula Bovet9.00 - 9.45 - KEYNOTE LECTURE
Mycotoxins and phycotoxinsChairperson : J Gilbert
MYCOTOXINS
Aula Pocchiari
Chairpersons : J Gilbert and M. JemmaliPlenary Lecture
PLM6 - microbial Ecology and mycotoxin formation
J. Smith, J. Lacey, R. Cuero, N. Ramakrishna, N. Gqaleni -
University of Strathclyde (UK)Contributed Papers
OM26 - Scientific Co-operation task on aflatoxins:
the co-ordinators view
A. E. Gleadle, E.M. Mortby, A. Hatch, R. Burt
OM27 - The effect of a commercial herbicide on aflatoxin and lipid
synthesis, in Aspergillus parasiticus (N1X)
A. A. Chuturgoon, R. Punchoo, S. Bux, M. F. Dutton
OM28 - Interactive effects of zinc and associated mycoflora in
toxigenic Fusarium DNA and Aspergillus in relation to
growth and toxins production
R.G. Cuero, T. Ouellet
OM29 - Freeze-dried mixed cultures of microfungi for proficiency tests
M. Olsen, K. Andersson, A. Rosengren
OM30 - Detection of aflatoxigenic moulds in grains by the polymerase chain reaction
R. Shapira, N. Paster, O. Eyal, M. Menasherov, A. Matt,
R. Salomon
OM31 - Regulation of sterigmatocystin biosynthesis during sporulation of Aspergillus nidulans
D. Guzman de Pena, J. Aguirre, J. Ruiz Herrera
OM32 - Aflatoxin production related with CO2/O2 rate in
Aspergillus Parasiticus
E. Finotti , C. Paolino, A. Ricelli, R. Mercantini
OM33 - Taxonomy and chemotaxonomy of mycotoxin producers:
how consistent is mycotoxin production in a species?
J.C. Frisvad, T. O. Larsen, J. Smedsgaard, M.S. Nielsen, P.V. Nielsen,
F. Lund, A. Svendsen, U. Thrane , O. Filtenborg14.30 - 15.30 Aula Marotta: Poster Session
Aula Pocchiari
Chairpersons: G. Piva and A. ViscontiPlenary Lecture
PLM7 - MOLECULAR EPIDEMIOLOGY OF MYCOTOXIN - RELATED HUMAN DISEASE
C.P. Wild - UNIVERSITY OF LEEDS (UK)
OM34 - Microbiological degradation of mycotoxins
E.M. Horvath, J. Binder, N. Ellend, J. Heidegger, E. Schaffer
OM35 - Development of a technique for the prediction/alleviation of
conditions leading to mould growth in houses
J.A. Clarke, J.E. Smith, J.G. Anderson, R.C. McLean, N.J. Rowan,
N.J. Kelly, C. Johnstone
OM36 - Moniliformin accumulation in wheat kernels inoculated with
Fusarium avenaceum
P.Golinski, I. Lasocka, M. Kostecki, H. Wisniewska, J. Chelkowski,
Z. Kaczmarek
17.05 - 17.20
OM37 - Ochratoxin A in ten rice cultivars after inoculation of
Aspergillus ochraceus
K. Axberg, G. Jansson, L.L. Ilag, T.W. Mew, K. HultCLOSING SESSION
17.40 - 18.00
H.P.van Egmond
P.G. Thiel
M. MiragliaFriday, 31 May
Aula Pocchiari
FAO/IUPAC Workshop
Chairperson: C. CanetMorning Session: 9.30 - 12.30
Introduction to the workshop on Mycotoxins: FAO activities
C. Canet - FAO
L.A. Esteves - NAPHIRE, The Philippines
O. Sanchez Regueiro - Instituto de nutricion e higiene, Cuba
E. Wilbald - Government Chemist Laboratory, TanzaniaAfternoon Session: 14.00 - 17.30
S. Resnik - University of Buenos Aires, Argentina
O. Sanchez Regueiro - Instituto de nutricion e higiene, Cuba
B. Doko - University of MontpellierOpen Discussion
Conclusions and Recommendations
Aula Bovet
SM&T Session
Chairperson: A. Boenke and J. Gilbert
SMT1 - The Standards, Measurements and Testing Programme (SM&T) -
The European Support to Standardisation, Measurements and Testing
Projects
A. Boenke
SMT2 - Improvements in the Determination of Fumonisins (FB1 and FB2)
in Maize and Maize Based Feeds
A. Visconti
SMT3 - The Development of Reference Materials for Paralytic Shellfish
Poisons (PSP) - Coordination, Management and other Relevant Project
Aspects
H.P. van Egmond
SMT4 - How to submit a Proposal to a call for proposal within
the EC, Standards, Measurements and Testing Programme (SM&T)
A. Boenke
Final proposers forum at the stand of the european commission,
SM&T ProgrammeLast Minute Announcement
Secretariat for Cultural Affairs
Istituto Superiore di Sanita
Viale Regina Elena, 299
00161 - Rome, Italy
Tel: +39-6-49902611 or 49902292
Fax: +39-6-4440235
Istituto Superiore di Sanita
Laboratorio Alimenti
Viale Regina Elena, 299 - 00161 Rome, Italy
Tel: +39-6-49902367 or 49902377
Fax: +39-6-49902377 or 4451767
E-Mail: miraglia@istan.interbusiness.it
Viale Pasteur, 5
00144 Rome, Italy
Tel: +39-6-5912284
Fax: +39-6-5916750