U.S. Food and Drug Administration
U.S. Environmental Protection Agency
July 2003



FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children.


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Table of Contents
  1. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. Welcome and Purpose of the Meeting
  2. One of a Series of Meetings Held by FDA and EPA
  3. Purpose of the Meeting
  4. Purpose of the Meeting
  5. Purpose of the Meeting
  6. Purpose of the Meeting
  7. Questions of clarification?
  8. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. Background
  9. Background
  10. Current FDA Advisory for Pregnant Women and Women of Childbearing Age
  11. Current EPA Advisory
  12. FAC 2002 - Charge
  13. FAC 2002 - Recommendations
  14. FAC 2002 - Recommendations
  15. Current Effort and Goal
  16. Questions of clarification?
  17. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. At Risk Population
  18. At-risk Population
  19. At-risk Population and Target of the Advisory
  20. How Effective are we?
  21. Blood Mercury Levels in US Children and Women of Childbearing Age 1999-2000 [JAMA 2003; 289:1667]
  22. Blood Mercury Levels in US Children and Women of Childbearing Age 1999-2000 [JAMA 2003; 289:1667]
  23. Blood Mercury levels
  24. Blood Mercury Levels in US Children and Women of Childbearing Age 1999-2000 [JAMA 2003; 289:1667]
  25. Questions of clarification?
  1. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. Estimating Exposure
  2. Exposure Assessment Outline
  3. Methods
  4. Methods
  5. Exposure Simulation
  6. Scenarios
  7. Scenarios (weekly consumptions)
  8. Results
  9. Conclusions
  10. Questions of Clarification?
  11. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. Determining the Desired Level of Protection
  12. Desired Level of Protection
  13. Risk Management Decision-making
  14. NHANES Blood Mercury Levels
  15. Establishing a Level of Protection
  16. Questions of clarification?
  17. FDA and EPA Development of a Joint Advisory for Methylmercury-containing Fish Consumption for Women of Childbearing Age and Children. Developing an FDA/EPA Advisory
  18. Current Methylmercury Advisory has Two Main Elements
  19. Risk Message
  20. Current Consumer Advice
  21. Current Advice on Non-commercial Fish
  22. FAC Recommendations
  23. Focus Group Testing of Approaches to Consumer Advice
  24. Questions of clarification
  25. Milestones and Tentative Time Line
  26. Next Steps
  27. General Discussion

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