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Patient Information Sheet
Nelarabine (marketed as Arranon)
PDF Print Version
This is a summary of the most
important information about Arranon. For details, talk to your
or your child’s healthcare professional.
What
Is Arranon?
Arranon is an
anti-cancer medicine used to treat adults and children who have:
- T-cell acute lymphoblastic
leukemia
- T-cell lymphoblastic lymphoma
At this time,
it is not known whether Arranon will improve symptoms, keep the
disease from getting worse, or help patients live longer.
Who Should Not Be
Treated With Arranon?
You or your
child should not be given Arranon if you or your child is
allergic to nelarabine, or to anything else in Arranon.
What Are The Risks?
The
following are the major potential risks and side
effects of Arranon therapy. However, this list is not
complete.
Call your
healthcare professional right away if you or your child has the
following symptoms:
- seizures
- numbness and tingling in the
hands, fingers, feet, or toes
- problems with fine motor skills such as buttoning
clothes
- unsteady while walking
- increased tripping while walking
- weakness when getting out of a
chair or walking up stairs.
These symptoms
may not go away even when treatment with Arranon is stopped.
- decreased blood
counts such as low red blood cells,
low white blood cells, and low platelets
Call your or
your child’s healthcare professional right away if you or your
child:
-
is more tired than usual, pale,
or has trouble breathing
-
has a fever or signs of an
infection
-
bruises easy or has any unusual
bleeding
Blood tests
should be done regularly to check blood counts.
- stomach area
problems such as nausea, vomiting,
diarrhea, and constipation
- some common side
effects that may occur with Arranon
include:
- headache
- sleepiness
- blurry eyesight
You or your
child should not drive or operate
dangerous machines during treatment with Arranon.
What Should I Tell My
Healthcare Professional?
Before
you or your child starts receiving Arranon, tell your
healthcare professional if you or your child:
- have any nervous
system problems.
- have kidney
problems.
- are pregnant,
planning to become pregnant, or are breast feeding.
Can Other Medicines Or
Food Affect Arranon?
Tell
your healthcare professional about all the medicines you or your
child takes including prescription and non-prescription
medicines, vitamins, and herbal supplements.
You
or your child should not receive vaccines made with live germs
during treatment with Arranon.
How
Should My Child or I Receive Arranon?
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Date Approved: October
2005
Date Created: December
1, 2005
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