HOME |  ABOUT HERBMED |  SPONSORS |  LINKS |  LICENSING |  HELP

 
SCIENTIFIC NAME:
Cinnamomum zeylanicum
FAMILY NAME:
Lauraceae
COMMON NAME:
Cinnamon
  Evidence for Efficacy (Human Data)
   Clinical Trials  (18)
   Observational Studies/Case Reports  (11)
   Traditional and Folk Use  (13)
  Safety Data
   Adverse Effects & Toxicity  (43)
   Interactions  (1)
   Contraindications  (2)
  Evidence of Activity
   Animal Studies  (17)
   Pharmacodynamics  (91)
   Analytical Chemistry  (23)
   Pharmacokinetics (ADME)  (1)
   Genetics & Molecular Biology  (5)
  Formulas/Blends
   Methods of Preparation  (14)
   Patents  (3)
   Folk Blends (component)  (0)
   Contemporary Mixtures (component)  (0)
  Other Information
   Pictures & Distribution Maps  (1)
   Cultivation, Conservation & Ecology  (4)
   Related Links  (3)
  Dynamic Updates
   Live PubMed Searches  (15)
  History of Records
   History of Record (1)
 
 
BACK TO HOME
EVIDENCE FOR EFFICACY (HUMAN DATA)
 
Clinical Trials
  Cinnamon reduces mean fasting serum glucose (18-29%), TAG (23-30%), total cholesterol (12-26%) and LDL-cholesterol (7-27%) in subjects with type 2 diabetes after 40 d of daily consumption of 1-6 g cinnamon. Anderson 2008
  Identification of five prospective randomized controlled trials (n = 282) shows cinnamon does not appear to improve A1C, FBG, or lipid parameters in patients with type 1 or type 2 diabetes. Baker 2008
  A combination botanical product which includes Cinnamomum zeylanicum, significantly reduced NSS during the 8 hours following nasal allergen challenge and marginally inhibited the release of prostaglandin D2 into nasal lavage fluid, suggesting utility in patients with allergic rhinitis. Corren 2008
  One placebo-controlled trial in patients with type 2 diabetes found that cinnamon intake was associated with favorable effects on fasting plasma glucose. None of the studies reported an improvement in HbA1C. [Article in Dutch] Kleefstra 2008
  The consumption of supplemental doses of turmeric, but not cinnamon, in healthy subjects can significantly increase urinary oxalate levels, thereby increasing risk of kidney stone formation in susceptible individuals. Tang 2008
  A prospective, double-blind, placebo-controlled design with 72 adolescent type 1 diabetic subjects indicates that cinnamon is not effective for improving glycemic control in adolescents with type 1 diabetes. Altschuler 2007
  Seven of 11 orofacial granulomatosis patients whose impressions were taken at least 3 months after the initiation of cinnamon- and benzoate-free diet showed reduction in lip size during follow up. Chiandussi 2007
  One randomized clinical trial reported that cassia cinnamon lowered total cholesterol, low-density lipoprotein cholesterol, and triglycerides; the other 2 trials, however, did not observe this effect. Dugoua 2007
  The intake of 6g cinnamon with rice pudding reduces postprandial blood glucose and delays gastric emptying without affecting satiety in healthy subjects. Hlebowicz 2007
  Cinnamon spice supplementation may be important to in vivo glycaemic control and insulin sensitivity in humans, and not only are its effects immediate, they appear to be sustained for 12 h. Solomon 2007
  A study on the effect of cinnamon extract on insulin resistance parameters in 15 patients with polycystic ovary syndrome (POS) revealed significant reductions in insulin resistance in the cinnamon group of women with POS but not in the placebo group. Wang 2007
  The odor-related terms 'garlic', 'cinnamon', 'jasmine'elicited activation in the primary olfactory cortex, which include the piriform cortex and the amygdale in a study conducted to investigate the abstract linking of linguistic and odor information using modern neuroimaging techniques. Gonz?z 2006
  The cinnamon extract seems to have a moderate effect in reducing fasting plasma glucose concentrations in diabetic patients with poor glycaemic control. Mang 2006
  Cinnamon supplementation (1.5 g/d) does not improve whole-body insulin sensitivity or oral glucose tolerance and does not modulate blood lipid profile in postmenopausal patients with type 2 diabetes. Vanschoonbeek 2006
  Intake of 1, 3, or 6g of cinnamon per day reduces serum glucose, triglyceride, LDL cholesterol, and total cholesterol in people with type 2 diabetes and inclusion of cinnamon in the diet of people with type 2 diabetes will reduce risk factors associated with diabetes and cardiovascular diseases. Khan 2003
  Prevention and treatment of oral candidiasis with cortex cinnamon solution [Article in Chinese] Cao 1993
  Saliva flow increase seen in 24 young adults after chewing gums flavored with cinnamon, peppermint, etc. The effect persists after 20 minutes Dawes 1992
  Sweetening spices studied on 70 adults found cinnamon, vanilla, spearmint and anise to be more comparable to sugar than nutmeg, ginger, cloves, bay, and salt Blank 1990

Microsoft OLE DB Provider for SQL Server error '80004005'

Timeout expired

/publisher/herb_display.asp, line 189

Observational Studies/Case Reports
  It is claimed that preparations containing cinnamon are suitable as dietetic food or food additive to regulate glucose metabolism in patients with type 2 diabetes because of its pharmacological effects on glucose tolerance, insulin resistance, insulin release & blood-sugar.[Article in German] Ammon 2008
  A case of a 68-year-old Caucasian female with type 2 diabetes mellitus who experienced an acute exacerbation of her rosacea 2 weeks after self-initiating cinnamon oil pills to lower her blood sugar levels was reported. Campbell 2008
  The case of a patient who was diagnosed with alllergic contact stomatitis due to cinnamon-flavoured chewing gum was reported. Tremblay 2008
  [Is it true that cinnamon can lower blood sugar in people with diabetes?] [No authors listed] 2007
  37 well-documented cases of cinnamon-induced contact stomatitis for clinical and histological features consistent with a diagnosis of orofacial granulomatosis was examined. Endo 2007
  Cinnamon has a possible modest effect in lowering plasma glucose levels in patients with poorly controlled type 2 diabetes. Pham 2007
  A case of long-lasting, extensive eczematous and bullous dermatitis affecting exposed areas (arms and legs), beginning within 24 hr after having a mud bath with cinnamon essential oil in a spa, in a 74-year-old woman, is reported. Garc?Abujeta 2005