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Site Profile
Basis for Development of an Exposure Matrix for
the Mallinckrodt Chemical Company St. Louis
Downtown Site and the St. Louis Airport Site, St.
Louis, Missouri
(Revised June 14, 2007)
 PDF 1.7 MB (222 pages)
Revision Includes: Reflects comments of the ABRWH.
Constitutes a total rewrite of the document. Modified Purpose and
Scope, and Appendix A to incorporate SEC information as instructed
by NIOSH. Made minor editorial changes to eliminate readily
discernable errors and eliminated extraneous intake tables. Added
information to reconstruct doses from available monitoring and
coworker data for the period 1949-1962, and to clarify some
discrepancies between the early-in-the program draft and current
guidance. Deleted Appendix D (which was formerly C). This revision
changes the method for assigning uranium, radium and thorium
coworker intakes and radon exposures and eliminates the application
of equilibrium amounts of uranium progeny intakes to reconstruct
dose. Incorporates formal internal and NIOSH review comments.
Revised dates for operational period in sections 6 and 7 to end in
1958. Removed references to unmonitored thorium and radium
exposures (since reconstruction of such exposures has been
determined to be not feasible by the SEC action). Added a section
titled "unmonitored raffinate exposures" to cover the period 1948 -
1958 and inserted the text "reserved" to indicate that reconstruction of
internal exposure from such pathways is not covered in this TBD for
the time period 1948 - 1958. This revision results in an increase in
assigned dose and a PER is required.
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Technical Information Bulletins (TIBs)
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Program Evaluation Reports (PERs) and Program Evaluation Plans (PEPs)
NIOSH is committed to applying the best available science in dose reconstructions. In keeping with this commitment, completed cases with probabilities of causation less than 50% are reviewed as relevant new information becomes available. The results of these reviews are described in a Program Evaluation Report (PER). The PER details the effect, if any, of the new information on the completed dose reconstruction. If it appears that the compensability of a completed dose reconstruction may be effected, NIOSH is committed to working with the Department of Labor to reopen and rework the dose reconstruction, as appropriate. A Program Evaluation Plan (PEP) describes plans for evaluating specific program details or issues.
Program Evaluation Report: Mallinckrodt TBD Revision
PDF 16 KB (2 pages)
Document Number: OCAS-PER-0015 Rev-00
About this Document: New document to determine which
previously completed claims require
evaluation for the effect of revising the
Mallinckrodt TBD.
Approved: July 31, 2007
Summary: It is not possible to determine the magnitude of the change to dose without a new dose estimate. Since (as of issuance of this PER) no Mallinckrodt claims have yet been completed with the newest revision to the TBD, NIOSH is requesting that all Mallinckrodt claims with a dose reconstruction performed using Revision 1 of ORAUT-TKBS-0005 that have a Probability of Causation less than 50% be returned for a new estimate. A list of the population of 16 potentially affected claims is attached. A new dose reconstruction will be completed for each of the claims using the latest revision to the Mallinckrodt TBD.
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Worker Outreach Activities
Based on a recommendation from the Advisory Board to provide workers and site experts with opportunities to participate in developing the technical documents used in dose reconstruction, NIOSH established a Worker Outreach Program.
At Worker Outreach Meetings, current and former DOE and AWE employees have opportunities to obtain information about Site Profiles, Technical Basis Documents, and Technical Information Bulletins, and to provide information for consideration and possible use in dose reconstruction. This process is valuable to ensure that the technical documents used in dose reconstruction contain correct and useful information.
Below are the Worker Outreach Activities for Mallinckrodt Chemical Co., Destrehan Street Plant:
At the current time, worker outreach activities have not been scheduled.
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Comments on Mallinckrodt Chemical Company Documents
How to Submit Comments
Comments on Mallinckrodt Chemical Company documents can be submitted to the NIOSH Docket Officer electronically by e-mail at NIOCINDOCKET@cdc.gov or printed comments can be mailed to NIOSH Docket Office, Robert A. Taft Laboratories, MS-C34, 4676 Columbia Parkway, Cincinnati, OH 45226. Please include the Site Profile Number (014) on all comments.
Comments Received
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Special Exposure Cohort Petition Information for Mallinckrodt Chemical Company
- Classes Added to the
SEC
- Mallinckrodt Chemical Works, Destrehan Street Facility (1942-1948)--employees of the DOE or DOE contractors or subcontractors employed by the Uranium Division of Mallinckrodt Chemical Works, Destrehan Street Facility, during the period from 1942 through 1948 and who were employed for a number of work days aggregating at least 250 work days either solely under this employment or in combination with work days within the parameters (excluding aggregate work day requirements) established for other classes of employees included in the SEC
- Mallinckrodt Chemical Works, Destrehan Street Facility (1949-1957)--Department of Energy (DOE) employees or DOE contractor or subcontractor employees who worked in the Uranium Division at the Destrehan Street Facility of Mallinckrodt Chemical Works from 1949 to 1957 and who were employed for a number of work days aggregating at least 250 work days either solely under this employment or in combination with work days within the parameters (excluding aggregate work day
requirements) established for other classes of employees included in the SEC
- Petition Information
- Location: All locations in the Destrehan Street Plant
Job Titles and/or Job Duties: All employees that conducted Atomic Energy Commission (AEC) work at the Destrehan Street Plant
Period of Employment: 1942-1957
- Location: St. Louis, Missouri
Job Titles and/or Job Duties: All employees who worked with uranium
Period of Employment: January 1, 1958 to December 31, 1958
- Federal Register Notice Announcing that the Mallinckrodt Chemical Company SEC Petition has met the Minimum Qualifications for Review and Evaluation
December 20, 2004 (1942-1957)
PDF 48 KB (1 page)
December 10, 2008 (January 1, 1958 to December 31, 1958)
PDF 16 KB (1 page)
- Copy of the Petition Received
Copy of the Petition Received Covering 1942-1957:
Pages 1-23
PDF 1.13 MB (23 pages)
Pages 24-47
PDF 1.67 MB (24 pages)
Page 48-70
PDF 1.04 MB (23 pages)
Copy of the Petition Received Covering 1958
PDF 88 KB (2 pages)
- SEC Petition Evaluation Report
SEC Petition Evaluation Report: SEC-00012-1
PDF 98 KB (26 pages)
SEC Petition Evaluation Report: SEC-00012-2
PDF 243 KB (48 pages)
Supplement to the SEC Petition Evaluation Reports for
Petitions SEC-00012-1 and 2
PDF 342 KB (17 pages)
SEC Petition Evaluation Report: SEC-00133
PDF 71 KB (19 pages)
- Petition Discussed by the Advisory Board
The Advisory Board discussed the Mallinckrodt Chemical Plant petition on February 8, 2005; April 27, 2005; July 6, 2006; and August 26,2005. A copy of the transcripts from these Advisory Board meetings are listed below:
February 8, 2005 Excerpt: Mallinckrodt SEC Petition Discussions
PDF 834 KB (256 pages)
April 27, 2005
PDF 578 KB (324 pages)
July 6, 2005
PDF 447 KB (250 pages)
August 26, 2005 Excerpt: Discussions on Mallinckrodt SEC Petition
PDF 125 KB (69 pages)
- Advisory Board Recommendation on SEC Petition
Mallinckrodt Chemical Plant SEC petition (1942-1948)
PDF 109 KB (2 pages)
Mallinckrodt Chemical Plant SEC petition (1949-1957)
PDF 475 KB (3 pages)
Mallinckrodt Chemical Plant SEC petition (1958)
PDF 526 KB (2 pages)
- HHS Letter to Congress Regarding the SEC Petition
Mallinckrodt Chemical Plant SEC petition 1942-1948
PDF 438 KB (9 pages)
Mallinckrodt Chemical Plant SEC petition 1949-1957
PDF 287 KB (8 pages)
- Federal Register Notice: Designation of a Class of Employees for Addition to the Special Exposure Cohort
Mallinckrodt Chemical Plant SEC petition 1942-1948
April 18, 2005
PDF 45 KB (1 page)
Mallinckrodt Chemical Plant SEC petition 1949-1957
November 4, 2005
PDF 46 KB (1 page)
- HHS Designation of Additional Members to the SEC
Mallinckrodt Chemical Plant SEC Designation for 1942-1948
PDF 445 KB (5 pages)
Mallinckrodt Chemical Plant SEC Designation for 1949-1957
PDF 294 KB (5 pages)
- Effective Date for the SEC Class
May 12, 2005--Mallinckrodt Chemical Plant SEC 1942 to 1948
November 13, 2005--Mallinckrodt Chemical Plant SEC 1949 to 1957
- Federal Register Notice: Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort
Mallinckrodt Chemical Plant SEC 1942-1948
May 23, 2005
PDF 45 KB (1 page)
Mallinckrodt Chemical Plant SEC 1949-1957
December 27, 2005
PDF 44 KB (1 page)
- Letter to DOL Regarding the Addition of a New Class of Employees to the SEC
Mallinckrodt Chemical Plant SEC 1942-1948
PDF 26 KB (1 page)
Mallinckrodt Chemical Plant SEC 1949-1957
PDF 409 KB (1 page)
Additional Letter to DOL regarding the handling of Mallinckrodt Cases for New SEC Class for 1949-1957
PDF 19 KB (1 page)
- Letter from DOL Regarding the Return of All Cases for the New SEC Class
Mallinckrodt Chemical Plant SEC 1942-1948
PDF 217 KB (2 pages)
Mallinckrodt Chemical Plant SEC 1949-1957
PDF 215 KB (3 pages)
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Previous Versions of Mallinckrodt Chemical Company Documents
Basis for Development
of an Exposure Matrix for the Mallinckrodt Chemical Company
St. Louis Downtown Site, St. Louis, Missouri, Period of
Operation: 1942-1958
(Revised March 10, 2005)
PDF 1.0 MB (248 pages)
Revision Includes: Incorporated comments on Section 8.0 and to incorporate additional lately captured information. Revision to incorporate comments on Sections 7.0 and 8.0; to incorporate additional lately captured information regarding site work and external and radon exposure rates; to incorporate neutron exposure information; to incorporate information about the St. Louis Airport Site (SLAPS); and to provide additional guidance to dose reconstructors. Section 7.0, regarding
external dose, remains on hold. Incorporated NIOSH comments.
Technical Basis Document: Basis for Development
of an Exposure Matrix for the Mallinckrodt Chemical Company
St. Louis Downtown Site, St. Louis, Missouri, Period of
Operation: 1942-1958
Approved October 24, 2003
PDF 632 KB (124 pages)
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Page last updated: December 23, 2008
Page last reviewed: May 30, 2008
Content Source: National Institute for Occupational Safety and Health (NIOSH)
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