PLoS Neglected Tropical Diseases: A Peer-Reviewed Open-Access Journal

Australia's Dengue Risk Driven by Human Adaptation to Climate Change
A Comparative Study of the Spatial Distribution of Schistosomiasis in Mali in 1984-1989 and 2004-2006
WR279,396, a Third Generation Aminoglycoside Ointment for the Treatment of Leishmania major Cutaneous Leishmaniasis: A Phase 2, Randomized, Double Blind, Placebo Controlled Study
Effects of a Five-Year Citywide Intervention Program To Control Aedes aegypti and Prevent Dengue Outbreaks in Northern Argentina
A Kernel for Open Source Drug Discovery in Tropical Diseases
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Featured Editorial

One World Health: Neglected Tropical Diseases in a Flat World

Globalization has emerged as an important force in revealing the devastating health and economic impact of disease on human populations worldwide.

Featured Review

Use of Mapping and Spatial and Space-Time Modeling Approaches in Operational Control of Aedes aegypti and Dengue

The authors review how these modeling approaches have been used to visualize and analyze mosquito vector and epidemiologic data for dengue, and they discuss the potential for these approaches to be included as routine activities in operational vector and dengue control programs.

Featured Research

Australia's Dengue Risk Driven by Human Adaptation to Climate Change

Nigel Beebe and colleagues say that drought-proofing Australia's urban regions by installing large domestic water tanks may enable Aedes aegypti to regain its foothold across the country and expand its range of possible infections.

A Comparative Study of the Spatial Distribution of Schistosomiasis in Mali in 1984-1989 and 2004-2006

Researchers find that, a decade after the conclusion of a donor-funded schistosomiasis control program in Mali, prevalence of the disease had regressed to pre-intervention levels, and clusters of infections occurred generally in the original areas.

Development and Evaluation of Two Simple, Rapid Immunochromatographic Tests for the Detection of Yersinia pestis Antibodies in Humans and Reservoirs

Minoarisoa Rajerison and colleagues develop and evaluate two tests, to detect specific plague antibodies, that can be used as alternative methods for plague diagnosis and surveillance.