The Genetic Signatures of Noncoding RNAs
John S. Mattick outlines the emerging evidence for non–protein-coding RNA involvement in key molecular genetic phenomena and in specific functions and phenotypes.
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Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz
The authors show that an evolutionarily conserved secreted protein, Neural Lazarillo (NLaz), is induced in response to stress signals in fruit flies, and that it is required for metabolic regulation.
The RNA Polymerase Dictates ORF1 Requirement and Timing of LINE and SINE Retrotransposition
After evaluating several potential time limiting steps, the authors show that the RNA polymerase type is an important early factor contributing to the divergent retrotransposition kinetics between LINEs and SINEs.
Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers
The authors propose a method for multiple testing correction called SLIDE: a Sliding-window approach for Locally Inter-correlated markers with asymptotic Distribution Errors corrected.
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