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Current Projects

  • Relationship between homocysteine and vitamin status and intake in the Framingham Heart Study.
  • Determinants of plasma homocysteine in NHANES III.
  • Relationship between homocysteine and cardiovascular disease in animal models.
  • Relationships of B vitamins and homocysteine to breast, colon, cervical, and prostate cancer.
  • MTHFR thermolability: effect of folate deficiency in human and in immortalized lymphocytes.
  • Analysis by Affinity HPLC of folate forms distribution in human biopsies.
  • Physiology and molecular biology of a common mutation of the MTHFR gene.