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Current Projects

  • Identifying and quantifying the flavonoid content of: blueberries, cranberries, and grapes; almonds, pistachios, and walnuts; and cocoa-based foods.
  • Determining the bioavailability of cranberry anthocyanins and other phenolic compounds in healthy older adults.
  • Determining the effect of almonds (rich in flavonoids and vitamin E) on biomarkers of oxidative stress, inflammation, and vascular reactivity in humans.
  • Investigating in vitro and in vivo the effect of age on quercetin bioavailability and metabolism due to changes in phase II enzyme activity.
  • Testing in rat dams the effects of a “Western” diet (high in fat and sugar, low in micronutrients) during pregnancy and lactation on obese phenotypes in their pups and the effects of dietary flavonoids, particularly isoflavones, on this relationship.
  • Investigating mechanisms of actions of soy isoflavones in weight management via modulation of lipolysis in adipose tissue and mitochondrial biogenesis and beta-oxidation in skeletal muscle of rats.