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Edward Dudek, Ph.D.

  Research Associate
Laboratory for Nutrition and Vision Research
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3094
Fax: (617) 556-3132
E-mail: edward.dudek@tufts.edu
Education Ph.D., Molecular Biology
Illinois Institute of Technology
Research Focus Effects of nutrition, oxidation, and protein degradation on etiology of age-related eye disorders; identification of lens or retinal substrates for the ubiquitin dependent pathway and of specific enzymes involved in the recognition of damaged proteins

Featured HNRCA Research Publications

Zhang X, Dudek EJ, Liu B, Ding L, Fernandes AF, Liang JJ, Horwitz J, Taylor A, Shang F. Degradation of c-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway. IOVS. 2007;48:4200-8.

Shang F, Dudek E, Liu Q, Boulton ME, Taylor A. Protein quality control by the ubiquitin proteolytic pathway: roles in resistance to oxidative stress and disease. Israel J Chem. 2006;46:145-158.

Dudek EJ, Shang F, Liu C, Valverde P, Hobbs ML, Taylor A. Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseases. FASEB J. 2005;19(12):1707-9.

Shang F, Lu M, Dudek EJ, Reddan JR, Taylor A. Vitamin C and vitamin E restore the resistance of GSH-depleted lens cells to H2O2. Free Radic Biol Med. 2003;34(5):521-530.

Dudek EJ, Shang F, Taylor A. H2O2-mediated oxidative stress activates NF-kappa B in lens epithelial cells. Free Radic Biol Med. 2001;31:651-8.

 

To see more of Dr. Edward Dudek's publications, please visit PubMed and search for "Dudek E."