|
- v Q-Z
- > Judy D. Ribaya-Mercado, Sc.D.
- > Susan B. Roberts, Ph.D.
- > Irwin H. Rosenberg, M.D.
- > Robert M. Russell, M.D.
- > Edward Saltzman, M.D.
- > Ernst J. Schaefer, M.D.
- > Jacob Selhub, Ph.D.
- > Fu Shang, Ph.D.
- > Barbara Shukitt-Hale, Ph.D.
- > Donald E. Smith, Ph.D., CMAR
- > Katherine Strissel, Ph.D
- > Guangwen Tang, Ph.D.
- > Allen Taylor, Ph.D.
- > Aron Troen, D. Phil.
- > Katherine L. Tucker, Ph.D.
- > Xiang-Dong Wang, M.D., Ph.D.
- > Elizabeth Whitcomb, Ph.D.
- > Richard J. Wood, Ph.D.
- > Dayong Wu, M.D., Ph.D.
- > Qing-Wu Yan, Ph.D.
- > Su-Ping Yang
- > Kyung-Jin Yeum, Ph.D.
|
Xiang-Dong Wang, M.D., Ph.D.
 |
Senior Scientist and Director
Nutrition and Cancer Biology Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3130
Fax: (617) 556-3344
E-mail: xiang-dong.wang@tufts.edu |
| Education |
M.D., Peking Medical University
Ph.D., Nutrition, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University |
| Research Focus |
Carotenoids; retinoids; carcinogenesis |
| Academic Appointments |
Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Associate Professor, Tufts University School of Medicine
Co-Leader, Nutrition and Cancer Prevention Program, Cancer Center, Tufts Medical Center |
| Selected Professional Affiliations |
American Society of Nutrition
American Society of Cancer Research |
| Board Certification |
Medicine (China) |
|
|
| Featured HNRCA Research Publications |
|
Lian F, and Wang X-D. Apo-10’-lycopenoic acid induces Nrf2-mediated expression of phase II detoxification and antioxidant enzymes in human bronchial epithelial cells. International Journal of Cancer. 2008;123:1262-1268.
Veeramachaneni S, Ausman LM, Choi SW, Russell RM and Wang X-D. High dose lycopene supplementation increases hepatic CYP2E1 protein and inflammation in alcohol fed rats. J Nutr. 2008;138:1329-1335.
Lian F, Smith D, Ernst H, Russell RM, Wang X-D. Lycopene metabolites, apo-10’-lycopenoic acid, inhibits the growth of lung cancer cells in vitro and suppresses lung carcinogenesis in A/J mice in vivo. Carcinogenesis. 2007;28:1567-1574.
Mernitz H, Smith D, Wood R, Russell RM, Wang X-D. Inhibition of Lung Carcinogenesis by 1alpha,25-Dihydroxyvitamin D3 and 9-cis Retinoic Acid in the A/J Mouse Model: Evidence of Retinoid Antagonism of Vitamin D Toxicity. International Journal of Cancer. 2007;120:1402-1409.
Kim Y, Lian F, Yeum KJ, Choi SW, Russell RM, Wang X-D. The Effects of Combined Antioxidant (beta-Carotene, alpha-Tocopherol and Ascorbic acid) Supplementation on Antioxidant Capacity, DNA Single-Strand Break and Regulation of Insulin Growth Factor-1/IGF-Binding Protein 3 in Ferret Model of Lung Cancer. International Journal of Cancer. 2007;120:1847-1854.
|
Other Recent Publications
Lee CW, Wang X-D, Chien KL, Ge Z, Rickman BH, Rogers AB, Varro A, Whary MT, Wang TC, and Fox JG. Vitamin C supplementation does not protect L-gulono-beta-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy. International Journal of Cancer. 2008;122:1068-1076.
Lian F and Wang X-D. Lycopene and Lung Cancer. In:Lycopene: Nutritional, Medical and Therapeutic Properties. Preedy VR and Watson RR (Eds), Enfield, NH: Science Publishers press. 2008:365-393.
Mernitz H and Wang X-D. The bioconversion of carotenoids into retinoids: Implications for cancer prevention. In:Vitamin A: New Research. Loessing IT (Ed), Hauppauge, NY: Nova Science Publishers. 2007:39-57.
Hu KQ, Liu C, Ernst H, Krinsky NI, Russell RM, Wang X-D. The Biochemical Characterization of Ferret Carotene-9’, 10’-Monooxygenase Catalyzing Cleavage of Carotenoids in vitro and in vivo. J Bio Chem. 2006;281(28):19327-19338.
Kim Y, Chongyviriyaphan N, Liu C, Russell RM, Wang X-D. Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model. Carcinogenesis. 2006;27:1410-1419.
Liu C, Russell RM, and Wang X-D. Lycopene supplementation prevents smoke-induced changes in p53, cell proliferation, and apoptosis in the gastric mucosa of ferrets. J Nutr. 2006;136:106-11.
Lian F, Hu KQ, Russell RM and, Wang X-D. Beta-Cryptoxanthin inhibits the growth of immortalized human bronchia epithelial cells and non-small cell lung cancer cells and up-regulates retinoic acid receptor-beta expression. International J Cancer. 2006; 119:2084-2089.
Mernitz H and Wang XD. Alcohol and Tobacco Smoke in Retinoid Metabolism and Signaling.. In:Alcohol, Tobacco and Cancer. Cho CH and Purohit V (Eds), Basel: KARGER. 2006:457-580.
Wang XD and Stace King. Effect of carotenoids on signal transduction pathways: Significance in lung cancer prevention. In:Nutrients and Genes Interaction in Cancer. Friso S and Choi SW (Eds), New York, NY: CRC Press. 2006:113-128.
Mernitz H, Smith DE, Zhu AX, Wang X-D. 9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2. Cancer Letters. 2006;244:101-108.
To see more of Dr. Xiang-Dong Wang's publications, please visit PubMed and search for "Wang XD."
|
|
|
|
|
