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Aron Troen, D. Phil.

Aron Troen

Scientist III
Vitamin Metabolism Laboratory
Nutrition and Neurocognition Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3366
Fax: (617) 556-3243
E-mail: aron.troen@tufts.edu

Education Ph.D., Physiological Sciences
Oxford University
Research Focus Relation of nutritional factors to age-related cognitive decline and neurodegenerative disease


Featured HNRCA Research Publications

Troen AM, Shea-Budgell M, Shukitt-Hale B, Smith DE, Selhub J, Rosenberg IH. B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. 2008. Proceedings of the National Academy of Sciences. In press.

Troen, A.M., Shukitt-Hale, B., Smith, D.E., Selhub, J., Rosenberg, I.H. Cognitive Impact Of Nutritional Hyperhomocysteinemia In Apolipoprotein-E Deficient Mice. Journal of Alzheimer’s Disease. 2006;9(4):381-392.

Kado, D., Karlamangla, A., Selhub, J., Huang, M., Troen, A., Rowe , J., Seema, T. Homocysteine Versus The Vitamins Folate, B12 And B6 As Predictors Of Cognitive Function In Older High Functioning Adults: Mac Arther Studies Of Successful Aging. American Journal of Medicine. 2005;118(2):161-167.

Troen, A.M. The Central Nervous System in Animal Models of Hyperhomocysteinemia. Progress in Psychopharmacology and Biological Psychiatry. 2005;29(7):1140-1151.

Troen, A.M., Rosenberg, I.H. Homocysteine and Cognitive Function. Seminars in Vascular Medicine. 2005;5(2):209-14.


Other Recent Publications

Johnson EJ, McDonald K, Caldarella SM, Chung H, Troen AM, Snodderly, DM. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutritional Neuroscience. 2008;11(2):75-83.

Kalmbach RD, Choumenkovitch SF, Troen AM, Jacques PF, D’Agostino R, Selhub J. Relations between the DHFR 19 base pair deletion polymorphism and measures of folate status in the Framingham Offspring Study. 2008. American Journal of Clinical Nutrition. in press.

Bernardo A, McCord M, Troen AM, Allison JD, McDonald MP. Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet. Neurobiol Aging. 2007;28(8):1195-205.

Troen AM, Shukitt-Hale B, Chao WH, Albuquerque B, Smith DE, Selhub J, Rosenberg J. The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. J Alzheimers Dis. 2006; 9(4):381-92.

Troen AM, Fraser D, Abdeen Z, Rosenberg IH. Child Nutrition Initiative in Israel and Palestine: Status of food security, micronutrient malnutrition, and behavioral change and communication programs. Food Nutr Bull. 2006;27(2):180-5.

Troen AM, Mitchell B, Sorensen B, Wener MH, Johnston A, Wood B, Selhub J, McTiernan A, Yasui Y, Oral E, Potter JD, Ulrich CM. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. Journal of Nutrition. 2006;136(1):189-94.

Spiegelstein O, Gould A, Wlodarczyk B, Tsie M, Lu X, Le C, Troen A, Selhub J, Piedrahita JA, Salbaum JM, Kappen C, Melnyk S, James J, Finnell RH. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicology and Applied Pharmacology. 2005;203(1):18-26.

Kado DM, Karlamangla AS, Huang MH, Troen A, Rowe JW, Selhub J, Seeman TE. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. American Journal of Medicine. 2005;118(2):161-7.

Troen, A. M., Lutgens, E., Smith, D.E., Rosenberg I.H., Selhub J. The Atherogenic Effect Of Excess Methionine Intake. Proceedings of the National Academy of Sciences. 2003;100(25):15089-150.

Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology Letters. 2003;145(2):167-74.

To see more of Dr. Aron Troen's publications, please visit PubMed and search for "Troen A."