Donald E. Smith, Ph.D., CMAR

Featured HNRCA Research Publications
	Scientist II and Manager Comparative Biology Unit 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3201 Fax: (617) 556-3344 E-mail: donald.smith@tufts.edu
Education	Ph.D., Veterinary Medicine Hokkaido University, Graduate School of Veterinary Medicine
Research Focus	Animal models for dietary/nutritional interventions related to aging and associated degenerative conditions
Academic Appointments	Clinical Assistant Professor, Nutrition, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Selected Professional Affiliations	American Association of Laboratory Animal Sciences
Fu X, Booth S, Smith D. Vitamin K Content of Rodent Diets: A Review. JALAS. 2007;46(4):8-12. Lian F, Smith D, Ernst, H, Russell R, Wang X. Apo-10’-lycopenic acid suppresses lung cell growth by activating retinoic acid receptor B in vitro and inhibits lung tumorigenesis in vivo in the A/J mouse model. Carcinogenesis. 2007;28:1567-1574. Lawenda B, Smith D, Xu L, Niemierko A, Silverstein J, Boucher Y, Kashiwagi S, Held K, Jain R, Loeffler J, Blumberg J. Do the Supplements EGCG or Vitamin E Cause a Radiomodifying Response on Tumors? A Pilot Study with Murine Breast Carcinoma. Journal of the Society for Integrative Oncology. 2007;5(1):11-7 Mernitz H, Smith D, Wood, Russell R, Wang X. Inhibition of Lung Carcinogenesis by 1?,25-Dihydroxyvitamin D3 and 9-cis Retinoic Acid in the A/J Mouse Model: Evidence of Retinoid Antagonism of Vitamin D Toxicity. Int J Cancer. 2006;120:1402-1407. Kim Y, Liu X, Liu C, Smith D, Russell R, Wang X. Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(methylnitroamino)-1-(3-pyridyl)-1-butanone (NNK): A Model for Human Lung Cancer. Cancer Letters. 2006;234:209-219.
Other Recent Publications Booth S, Peterson J, Smith D, Shea K, Chamberland J, Crivello N. Age and dietary form of vitamin K affect menaquinone-4 concentrations in male Fischer 344 rats. J Nutr. 2008;138:492-496. Liu Z, Choi S, Crott J, Crott J, Smith D, Mason J. Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2. Int J Cancer. 2008;123:519-512. Mernitz H, Smith DE, Zhu AX, Wang X-D. 9-cis Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2. Cancer Letters. 2006;244:101-108. To see more of Dr. Donald E. Smith's publications, please visit PubMed and search for "Smith DE."