Zhenhua Liu, Ph.D.

Selected Research Publications
	Scientist III Vitamins and Carcinogenesis Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3117 Fax: (617) 556-3309 E-mail: zhenhua.liu@tufts.edu
Education	Ph.D Nutrition, Auburn University, Alabama M.S. Statistics, Auburn Unveristy, Alabama M.S. Animal Sciences, China Agricultural University, Beijing, China B.S. Animal Sciences, Hunan Agricultural University, Hunan, China
Research Focus	Epigenetic/genetic mechanisms underlying the mediation of tumorigenic pathways by one-carbon metabolism and related gene variances. Nutrition and biomarkers that may be in relation to the prevention of cancer and other diseases.
Selected Professional Affiliations	American Association of Cancer Research
Liu, Z. S. Choi, J. W. Crott, J. B. Mason. *Inadequate intake of multiple B-vitamins amplifies alterations in p53* expression and function induced by isolated folate depletion. International Journal of Cancer. 2008;123:519-525. Crott, J. W., Z. Liu, M. K. Keyes, S. Choi, H. Jang, M. P. Moyer, J. B. Mason. Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling, and folate uptake in human colonic epithelial cell lines. Journal of Nutritional Biochemistry. 2008;19:328-335. Liu, Z., S. Choi, J. W. Crott, M. K. Keyes, H. Jang, D. E. Smith, M. Kim, P. W. Laird, R. Bronson, J. B. Mason. Mild depletion of dietary folate combined with other B-vitamins alters multiple components of the Wnt pathway in the mouse colon. Journal of Nutrition. 2007;137:2701-2708. Keys, M. K, H. Jang, J. B. Mason, Z. Liu, J. W. Crott, D. E. Smith, S. Friso, S. Choi. Elder age and dietary folate are interactive determinants of genomic and p16-specific DNA methylation in the mouse colon. Journal of Nutrition. 2007;137:1713-1717. Crott, J. W., Z. Liu, S. Choi, J. B. Mason. Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5–8 of the gene.** Mutation Research. 2007;626:171-179. To see more of Dr. Zhenhua Liu's publications, please visit PubMed and search for "Liu Z."