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Tomoaki Uchiki, Ph.D.

 

Postdoctoral Associate
Laboratory for Nutrition and Vision Research
Jean Mayer USDA HNRCA at Tufts University
711 Washington St.
Boston, MA 02111-1524
Phone: 617-556-3160
Fax: 617-556-3344
E-mail: tomoaki.uchiki@tufts.edu

Education

Ph.D., The University of Tennessee-Oak Ridge National Laboratory

Research Focus

Intracellular degradation of advanced glycation end products (AGEs); Asking how eukaryotic intracellular proteolytic systems handle stresses caused by protein-modifying agents produced during hyper glycemia.

Selected Research Publications

Xu, H., Faber, C., Uchiki, T., Fairman, J. W., Racca, J., and Dealwis, C. Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation. Proc Natl Acad Sci U S A. 2006;103:4022-4027.

Uchiki, T., Dice, L.T., Hettich, R.L., and Dealwis, C. Identification of Phosphorylation Sites on the Yeast Ribonucleotide Reductase Inhibitor Sml1. Journal of Biological Chemistry. 2004;279:11293-303.

Uchiki, T., Hettich, R.L., Gupta, V., and Dealwis, C. Characterization of Monomeric and Dimeric Forms of Recombinant Sml1p-histag Protein by Electrospray Mass Spectrometry. Analytical Biochemistry. 2002;301:35-48.