Weimin Guo, Ph.D.

Featured Research Publications
	Research Associate Vascular Biology Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3158 Fax: (617) 556-3224 E-mail: weimin.guo@tufts.edu
Education	Ph.D., Hematology - Thrombosis and Hemostasis, Shanghai Institute of Hematology, Rui-Jin Hospital, Shanghai Second Medical University
Research Focus	Role of dietary components, in particular, catechins on age-associated changes in vascular function. Studies examine the molecular mechanisms of effect of catechins on atherosclerosis
Selected Professional Affiliations	American Society for Biochemistry and Molecular Biology
Weimin Guo, Mitchell L. Wise, F. William Collins and Mohsen Meydani. Avenanthramides, Polyphenols from Oats, Inhibit IL-1β-Induced NF-κB Activation in Endothelial Cells. Free Radical Biology & Medicine. 2007;44(3):415-29 Shaun K Rodriguez, Weimin Guo, Liping Liu, Michael A. Band, Eric K. Paulson, Mohsen Meydani. Green Tea Catechin, Epigallocatechin-3-gallate (EGCG) Inhibits Vascular Endothelial Growth Factor Angiogenic Signaling by Disrupting the Formation of a Receptor Complex.* International Journal of Cancer 2005. 118(7):1635-1644 (co-first author). Weimin Guo, Fu Shang, Qing Liu, Lyudmila Urim, Minlei Zhang, Allen Taylor. Ubiquitin–proteasome pathway function is required for lens cell proliferation and differentiation.* Investigative Ophthalmology & Visual Science. 2006;47(6):2569-2575 Carla Marques, Weimin Guo, Paulo Pereira, Allen Taylor, Cam Patterson, Paul C. Evans, Fu Shang. The triage of damaged proteins: Degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones. FASEB J. 2006;20(6):741-743 (co-first author). Weimin Guo, Fu Shang, Qing Liu, Lyudmila Urim, Judith West-Mays, Allen Taylor. Differential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiation.* Investigative Ophthalmology & Visual Science. 2004;45(4):1194-1201
Other Recent Publications Dayong Wu, Zhihong Ren, Munkyong Pae, Weimin Guo, Xuelin Cui, Alfred H. Merrill, and Simin Nikbin Meydani. Aging Up-Regulates Expression of Inflammatory Mediators in Mouse Adipose Tissue. The Journal of Immunology. 2007;179(7):4829-4839. Alexandr Fernandes, Weimin Guo, Xinyu Zhang, Mathew Gallagher, Mircea Ivan, Allen Taylor, Paulo Pereira, Fu Shang. Proteasome-dependent regulation of signal transduction in retinal pigment epithelial. Experimental Eye Research. 2006;83(6):1472-81. Qing Liu, Fu Shang, Elizabeth Whitcomb, Weimin Guo, Wei Li, Allen Taylor. Ubiquitin-conjugating enzyme 3 delays human lens epithelial cells in metaphase. Investigative Ophthalmology & Visual Science. 2006;47(4):1302-1309. Jong-Deog Kim, Liping Liu,Weimin Guo, Mohsen Meydani. Chemical structure of flavonols in relation to modulation of angiogenesis and immune-endothelial cell adhesion. The Journal of Nutritional Biochemistry. 2006;17(3):165-176. Fu Shang, Gejing Deng, Qing Liu, Weimin Guo, Arthur L. Haas, Bernat Crosas, Daniel Finley, and Allen Taylor. Lys6-modified Ubiquitin Inhibits Ubiquitin-dependent Protein Degradation. The Journal of Biological Chemistry. 2005;280(21):20365-20374. Qing Liu, Fu Shang, Weimin Guo, Paloma Valverde and Allen Taylor. Regulation of the ubiquitin proteasome pathway in human lens epithelial cells during the cell cycle. Experimental Eye Research. 2004;78(2):197-205. To see more of Dr. Weimin Guo's publications, please visit PubMed and search for "Guo W."