Publications

Chiu, C-J, and Taylor A. Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res. 2007;84:229-45.

Chiu, C-J., Milton, R.C., Klein, R., Gensler, G., and Taylor, A., Dietary glycemic index is related to progression of age-related macular degeneration: A prospective study from the Age-Related Eye Diseases Study. Am J Clin Nut. 2007;86:1210-8.

Zhang X, Dudek, EJ, Liu B, Ding L, Fernandes AF, Liang JJ, Horwitz J, Taylor A, Shang F. Degradation of C-terminal Truncated αA-crystallins by the Ubiquitin Proteasome Pathway. Invest Ophthalmol Vis Sci. 2007;48:4200-8.

Chiu, CJ, Milton, R.C., Ferris III, F.L., Gensler, G, and Taylor A. Dietary carbohydrate and glycemic index in relation to Age-Related Macular Degeneration – The Age-Related Eye Disease Study. Am J Clin Nut. 2007;86:180-188

Zetterberg, M., Zhang, X., Taylor, A., Liu, B., Liang J.J., Shang, F. Glutathiolation enhances the degradation of yC-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway. Invest Ophthalmol Vis Sci. 2006;47:3467-73

Chiu, CJ, Milton, R.C., Ferris III, F.L., Gensler, G, and Taylor A. Dietary carbohydrate and glycemic index in relation to cortical and nuclear lens opacities – The Age-Related Eye Disease Study. Am J Clin Nut. 2006;83:1177-1184.

Liu Q, Shang F , Zhang X, Li W, Taylor A. Expression of K6W-ubiquitin inhibits proliferation of human lens epithelial cells. Mol Vis. 2006;12:931-6.

Guo, W., Shang, F., Taylor, A. Proteasome pathway is required for lens cell proliferation and differentiation. Invest Ophthalmol Vis Sci. 2006;47:2569-2575.

Chiu, C-J., Morris, M. S., Jacques, P. F. , Rogers, G., Chylack, L.T. Jr., Hankinson, S. E., Willett, W. C., Taylor, A. Long-term dietary carbohydrate intake, glycemic index and odds for early age-related macular degeneration. Am J Clin Nut. 2006;83:880-886.

Shang, F., Deng, G., Nowell, T. R., Haas, A.L., and Taylor, A. K6-Modified Ubiquitin interferes with 26S proteasome binding and inhibits deconjugation and ubiquitin-dependent proteolysis. J Biol Chem. 2005;280:20365-74.

Dudek, E., Shang, F., Q. Liu, Q., Hobbs, M., Taylor A. Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseases. FASEB J. 2005;19:1707-9.

Lu, M.,Taylor, A., Chylack, LT, Hankinson, SE, Willett, WC, Jacques, PF. Dietary fat intake and early age-related lens opacities. Am J Clin Nut. 2005;81:773-9.

Jacques, P., Taylor, A., Moeller, S., Hankinson, S.E., Rogers, G., Tung, W., Ludvico, J., Willett, W.C., Chylack, L.T. Long-term nutrient intake and five-year change in nuclear opacities. Arch Ophthalmol. 2005;123:517-26.

Guo, W., Shang, F., Urim, L., West-Mays, J., Zelenka, P., Taylor, A. Differential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiation. Invest Ophthalmol Vis Sci. 2004;4:1194-1201.

Shang, F, Taylor, A. Function of the ubiquitin proteolytic pathway in the eye. Exp Eye Res. 2004;78:1-14.

Learn More

For more information about the Nutrition and Vision Research Laboratory, please visit the USDA, Agricultural Research Service.

Out of Sight
Vision loss is an inevitable part of aging. What you eat could help forestall it.

A Link Between Carbohydrate Quality and Vision Loss is Strengthened by New Data

Low Carbs Better for Eyesight
Limiting refined carbohydrates may stall age-related macular degeneration.

Study: Some High-Sugar Foods Linked To Vision Loss
A recent study by Tufts nutrition researchers found that the development of age-related macular degeneration may be tied to over consumption of certain carbohydrates.