Publications

Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph J.A. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol Aging. 2007;28:1187-1194.

Lau, F.C., Bielinski, D.F., and Joseph, J.A. Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia. J Neurosci Res. 2007;85:1010-1017.Shukitt-Hale, B., Carey, A., Simon, L., Mark, D.A., and Joseph, J.A. The effects of grape juice on cognitive and motor deficits in aging. Nutrition. 2006;22:295-302.

Joseph, J.A., Fisher, D.R., Carey, A.N., Neuman, A., and Bielinski, D.F. Dopamine-induced stress signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes is partially mediated via the i3 loop and antagonized by blueberry extract. J Alz Dis. 2006;10:423-437.

Joseph, J.A., Fisher, D.R., and Bielinski, D. Blueberry extract alters oxidative stress-mediated signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes. J Alz Dis. 2006;9:35-42.

Joseph, J.A., Shukitt-Hale, B., and Casadesus, G. Reversing the deleterious effects of aging on neuronal communication and behavior: The beneficial properties of fruit polyphenolics. Amer J Clin Nutr. 2005;81(Suppl.):313S-316S.

Andres Lacueva, C., Shukitt-Hale, B., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr. Neurosci. 2005;8:111-120.

Joseph, J.A., Fisher, D.R. and Carey, A.N. Fruit extracts antagonize AB or DA induced deficits in CA2+ flux in M1 transfected COS 7 cells. J Alz Dis. 2004;6:403-411.

Shukitt-Hale, B., McEwen, J.J., Szprengiel, A., and Joseph, J.A. Effect of age on the radial arm water maze - a test of spatial learning and memory. Neurobiol Aging. 2004;25:223-229.

Casadesus, G., Shukitt-Hale, B., Stellwagen, H.M., Zhu, X., Lee, H-G., Smith, M.A., and Joseph, J.A. Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutr Neurosci. 2004;7:309-316.

Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt Hale, B., and Morgan, D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci. 2003;6:153-162.

Wilson, M.A., Shukitt-Hale, B., Kalt, W., Ingram, D.K., Joseph, J.A., and Wolkow, C.A. Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans. Aging Cell. 2006;5:59-68.Youdim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C., and Joseph, J.A. Short-term dietary supplementation of blueberry polyphenolics: Beneficial effects on aging brain performance and peripheral tissue function. Nutr Neurosci. 2000;3:383-397.

Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J. and Bickford, P.C. Reversals of age related declines in neuronal signal transduction, cognitive and motor behavioral deficits with diets supplemented with blueberry, spinach or strawberry dietary supplementation. J Neurosci. 1999;19:8114-8121.

Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Prior, R.L., Cao, G., Martin, A., Taglialatela, G., and Bickford, P.C. Long-term dietary strawberry, spinach or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J Neurosci. 1998;18: 8047-8055.