Publications

Hamer DH, Sempertegui F, Estrella B, Tucker KL, Rodriguez A, Egas J, Dallal GE, Selhub J, Griffiths JK, Meydani SN. Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians. J Nutr., 2009, 139: 113-119

Falsey AR, Dallal GE, Formica MA, Andolina GG, Hamer DH, Fine BC, Leka LL, Meydani SN. Long-term care facilities: A cornucopia of viral Pathogens. JAGS; 2008, 56: 1281-1285

Wu D and Meydani SN. Age-associated changes in immune and inflammatory response: role of nutritional intervention. J. Leuk. Biol. 2008; 84-900-914.

Ren Z, Guo Z, Meydani SN, Wu D. White button mushroom enhances maturation of bone marrow derived dendritic cells and their antigen presenting function in mice. J Nutr. 2008; 138:544-550.

Wu D, Ren Z, Pae M, Guo W, Cui X, Merrill AH, Meydani SN. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J Immunol. 2007; 179:4829-39.

Meydani SN, Barnett JB, Dallal GE, Fine BC, Jacques PF, Leka LS, Hamer DH.ï¿½Serum zinc and pneumonia in nursing home elderly. AJCN. 2007; 86:1167-73.

Wu D, Pae M, Ren Z, Guo Z, Smith D, Meydani SN. Dietary Supplementation with White Button Mushroom Enhances Natural Killer Cell Activity in C57BL/6 Mice. J Nutr. 2007; 137:1472-1477.

Marko GM, Ahmed T, Bunnell SC, Wu D, Chung H, Huber BT, Meydani SN. Age-associated decline in effective immune synapse formation of CD4+ T cells is reversed by vitamin E supplementation. J Immunol. 2007; 178:1443-1449.

Gay RT, Belisle S, Beck MA, Meydani SN. An aged host promotes the evolution of an avirulent coxsackievirus into a virulent strain. PNAS. 2006; 103: 13825-13830.

Han SN, Adolfsson O, Lee C-K, Prolla TA, Ordovas J, Meydani SN. Age and vitamin E-induced changes in Gene Expression Profiles of T cells. J. Immunol, 2006; 177: 6052-6061.

Sempï¿½rtegui F, Estrella B, Elmieh N, Jordan M, Ahmed T, Rodrï¿½guez A, Tucker KL, Hamer DH, Reeves PG, Meydani SN. Nutritional, immunological, and health status of the elderly population living in poor neighborhoods of Quito, Ecuador. Br. J Nutr. 2006; 96:845-853.

Wu D, Han SN, Meydani M, Meydani SN. Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind controlled trial. JACN. 2006; 25:300-306.

Meydani SN, Leka LS, Fine BC, Dallal GE, Keusch GT, Singh MF, Hamer DH. Vitamin E and respiratory infections among elderly nursing home residents: a randomized controlled trial. JAMA. 2004; 292:828-836.

Han SN, Leka LS, Lichtenstein AH, Ausman LM, Schaefer EJ, Meydani SN. Effect of therapeutic lifestyle change (TLC) on immune function of moderately hypercholesterolemic humans. J Lipid Research. 2003; 44:2304-2310.

Wu D, Marko M, Claycombe K, Paulson KE, Meydani SN. Ceramide-induced and age-associated increase in macrophage COX-2 expression: role of NF-kappaB. J Biol Chem. 2003; 278:10983-10992.

Claycombe, KJ, Wu D, Nikolova-Karakashian M, Palmer H, Beharka A, Paulson KE and Meydani SN. Ceramide mediates age-associated increase in macrophage cyclooxygenase (COX-2) expression. J Biol Chem. 2002; 277:30784-30791.ï¿½

Adolfsson O, Huber BT, Meydani SN.ï¿½ Vitamin E-enhanced IL-2 production in old mice: naï¿½ve but not memory T cells show increased cell division cycling and IL-2 producing capacity.ï¿½ J Immunol. 2001; 167:3809-3817.

Han SN, Wu D, Ha WK, Beharka AA, Smith D, Bender BS, Meydani SN. Vitamin E supplementation increases Th1 cytokine production in old mice infected with influenza virus infection.ï¿½ Immunology. 2000;100:487-493.

Meydani SN, Meydani M, Blumberg JB, Leka LS, Siber G, Loszewski R, Thompson C, Pedrosa MC, Diamond RD, Stollar BD.ï¿½ Vitamin E supplementation and in vivo immune response in healthy elderly subjects: A randomized controlled trial.ï¿½JAMA. 1997; 277:1380-1386.

Learn More

For more information about the Nutritional Immunology Laboratory, please visit the USDA, Agricultural Research Service.

Struggle and Inspiration
Tufts symposium tackles difficult issues facing women in the science, medicine and engineering fields.

Healthy Fungus
White button mushrooms appear to boost immune function

Vitamin E: Infection Prevention
Vitamin E supplements may play an important role in preventing colds and other upper respiratory infections

Study: Zinc Boosts Immunity In Elderly
Maintaining normal zinc levels can help elderly patients ward off pneumonia.

Ask the Professor
Is frozen yogurt as nutritious as regular yogurt? Live cultures such as acidophilus are an important ingredient in regular yogurt; what happens to them when the yogurt is frozen?