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- v Q-Z
- > Judy D. Ribaya-Mercado, Sc.D.
- > Susan B. Roberts, Ph.D.
- > Irwin H. Rosenberg, M.D.
- > Robert M. Russell, M.D.
- > Edward Saltzman, M.D.
- > Ernst J. Schaefer, M.D.
- > Jacob Selhub, Ph.D.
- > Fu Shang, Ph.D.
- > Barbara Shukitt-Hale, Ph.D.
- > Donald E. Smith, Ph.D., CMAR
- > Katherine Strissel, Ph.D
- > Guangwen Tang, Ph.D.
- > Allen Taylor, Ph.D.
- > Aron Troen, D. Phil.
- > Katherine L. Tucker, Ph.D.
- > Xiang-Dong Wang, M.D., Ph.D.
- > Elizabeth Whitcomb, Ph.D.
- > Richard J. Wood, Ph.D.
- > Dayong Wu, M.D., Ph.D.
- > Qing-Wu Yan, Ph.D.
- > Su-Ping Yang
- > Kyung-Jin Yeum, Ph.D.
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Jacob Selhub, Ph.D.
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Senior Scientist and Director
Vitamin Metabolism Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3191
Fax: (617) 556-3166
E-mail: jacob.selhub@tufts.edu |
| Education |
Ph.D., Biochemistry
Case Western Reserve University |
| Research Focus |
Relationship between B vitamin nutriture, homocysteine, and vascular disease |
| Academic Appointments |
Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University |
| Selected Professional Affiliations |
Editorial Board, Nutritional Biochemistry
Consultant on Folate Fortification, Israeli Government |
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| Featured HNRCA Research Publications |
| Morris, M.S., Jacques, P., Rosenberg, I., Selhub, J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. American Journal of Clinical Nutrition. 2007;85(1):193-200.
Kado, D.M., Karlamangla, A.S., Huang, M., Troen, A., Rowe, J.W., Selhub, J., Seeman, T.E. Homocysteine versus the vitamins folate, B6 and B12 as predictors of cognitive function and decline in older high functioning adults: MacArthur Studies of Successful Aging. American Journal of Medicine. 2005;118(2):161-167.
Poo-Prieto, R., Haytowitz, D.B., Holden, J.M., Rogers, G., Choumenkovitch, S.F., Jacques, P.F., Selhub, J. Use of the affinity/HPLC method for quantitative estimation of folic acid enriched cereal grain products. Journal of Nutrition. 2006;136:3079-3083.
Mclean, R.R., Jacques, P.F., Selhub, J., Tucker, K.L., Samelson, E.J., Broe, K.E., Hannan, M.T., Cupples, A.L., Kiel, D.P. Plasma homocysteine concentrations predict the risk of hip fracture in elderly men and women: the framingham study. New England Journal of Medicine. 2004;350(20):2042-9.
Chiang, E.I., Smith, D.E., Selhub, J., Dallal, G., Roubenoff, R. Inflammation causes tissue-specific depletion of vitamin b6. Arthritis Research and Therapy. 2005;7(6):R1254-62.
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Other Recent Publications
Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB Sr, Wang TJ, Vasan RS. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation. 2007;116(9):984-92.
Mason JB, Dickstein A, Jacques PF, Haggarty P, Selhub J, Dallal G, Rosenberg IH. A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev. 2007;16(7):1325-9.
Levy D, Hwang SJ, Kayalar A, Benjamin EJ, Vasan RS, Parise H, Larson MG, Wang TJ, Selhub J, Jacques PF, Vita JA, Keyes MJ, Mitchell GF. Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study. Circulation. 2007;115(24):3079-85.
Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS. Multiple biomarkers and the risk of incident hypertension. Hypertension. 2007;49(3):432-8.
Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, Rifai N, Selhub J, Robins SJ, Benjamin EJ, D'Agostino RB, Vasan RS. Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med. 2006;355(25):2631-9.
Lievers KJ, Kluijtmans LA, Blom HJ, Wilson PW, Selhub J, Ordovas JM. Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study. Eur J Hum Genet. 2006;14(10):1125-9.
Troen AM, Shukitt-Hale B, Chao WH, Albuquerque B, Smith DE, Selhub J, Rosenberg J. The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. J Alzheimers Dis. 2006;9(4):381-92.
Anguera MC, Field MS, Perry C, Ghandour H, Chiang EP, Selhub J, Shane B, Stover PJ.Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. J Biol Chem. 2006;281(27):18335-42.
Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF, Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J, Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M. The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry. 2006;21(6):519-28.
Selhub J.The many facets of hyperhomocysteinemia: studies from the Framingham cohorts. J Nutr. 2006;136(6 Suppl):1726S-1730S.
To see more of Dr. Jacob Selhub's publications, please visit PubMed and search for "Selhub J."
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