Allen Taylor, Ph.D.

Featured HNRCA Research Publications
	Senior Scientist and Director Laboratory for Nutrition and Vision Research Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3156 Fax: (617) 556-3132 E-mail: allen.taylor@tufts.edu
Education	Ph.D., Organic Chemistry Rutgers University
Research Focus	Research focus: the role of the ubiquitin pathway in the regulation of cell proliferation, differentiation and protein quality in the lens and retina.
Academic Appointments	Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University Professor, Biochemistry, Sackler School of Graduate Biomedical Sciences Associate Professor, Ophthalmology, Tufts University School of Medicine
Selected Professional Affiliations	Senior Fullbright Fellow Guggenheim Fellow Denham Harmon Award for Excellence in Aging Research Osborn and Mendel Award for Excellence in Nutrition Research
For more information on Dr. Allen Taylor, please visit the USDA, Agricultural Research Service.
Shang, F., Taylor, A. Function of the ubiquitin proteolytic pathway in the eye. Exp Eye Res. 2004;78:1-14. Shang, F., Deng, G., Nowell, T. R., Haas, A.L., Taylor, A. K6-Modified Ubiquitin interferes with 26S proteasome binding and inhibits deconjugation and ubiquitin-dependent proteolysis. J Biol Chem. 2005;280:20365-74. Chiu, CJ, Milton, R.C., Ferris III, F.L., Gensler, G., Taylor A. Dietary carbohydrate and glycemic index in relation to cortical and nuclear lens opacities – The Age-Related Eye Disease Study. Am J Clin Nut. 2006;83:1177-1184. Chiu, CJ, Milton, R.C., Ferris III, F.L., Gensler, G, and Taylor A. Dietary carbohydrate and glycemic index in relation to Age-Related Macular Degeneration – The Age-Related Eye Disease Study. Am J Clin Nut. 2007;86:180-188. Chiu CJ, Milton RC, Klein R, Gensler G, Taylor A. Dietary carbohydrate and the progression of age-related macular degeneration: a prospective study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2007;86:1210-1218.
Other Recent Publications Zetterberg, M., Zhang, X., Taylor, A., Liu, B., Liang J.J., Shang, F. Glutathiolation enhances the degradation of {gamma}C-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway. Invest Ophthalmol Vis Sci. 2006;47:3467-73. Lu, M., Taylor, A., Chylack, LT, Rogers, G., Hankinson, SE, Willett, WC, Jacques, PF. Dietary linolenic acid intake is positively associated with five-year change in eye lens nuclear density. J Am Col Nut. 2007;26:133-140. Chiu C-J, Taylor A. Nutritional Antioxidants and age-related cataract and maculopathy. Exp Eye Res. 2007;84(2):229-45. Fernandes AF, Guo W, Zhang X, Gallagher M, Mircea I, Taylor A, Pereira P, Shang F. Proteasome-dependant regulation of signal transduction in retinal pigment epithelial cells. Exp Eye Res. 2006;83(6):1472-81. Liu Q, Shang F, Zhang X, Li W, Taylor A. Expression of K6W-ubiquitin inhibits proliferation of human lens epithelial cells. Mol Vis. 2006;12:931-6. Shang, F., Dudek, E., Liu, Q., Boulton, M., Taylor, A. Protein Quality Control by the Ubiquitin Proteolytic Pathway: roles in resistance to oxidative stress and disease. J Chem. 2006;46:145-158. Guo W, Shang F, Liu Q, Urim L, Zhang M, Taylor A. Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation. Invest Ophthamol Vis Sci. 2006;47(6):2569-75. Chiu C-J, Hubbard LD, Armstrong J, Rogers G, Jacques PF, Chylack LT, Hankinson SE, Willett WC, Taylor A. Dietary Glycemic Index and Carbohydrate in Relation to Early Age-Related Macular Degeneration. Am J Clin Nutr. 2006;83(4):880-6. Liu Q, Shang F, Whitcomb E, Guo W, Li W, Taylor A. Ubiquitin-conjugating enzyme 3 delays human lens epithelial cells in metaphase. Invest Ophthamol Vis Sci. 2006;47(4):1302-9. Chiu CJ, Rogers G, Morris MS, Jacques PF, Chylack LT, Tung W, Hankinson SE, Willett WC, Taylor A. Carbohydrate intake and glycemic index in relation to the odds of early cortical and nuclear lens opacities. Am J Clin Nutr. 2005;81(6):1411-1416. To see more of Dr. Allen Taylor's publications, please visit PubMed and search for "Taylor A."

More about Dr. Taylor's Research

Visit the USDA, Agricultural Research Service.

Out of Sight
Vision loss is an inevitable part of aging. What you eat could help forestall it.

A Link Between Carbohydrate Quality and Vision Loss is Strengthened by New Data

Low Carbs Better for Eyesight
Limiting refined carbohydrates may stall age-related macular degeneration.

Study: Some High-Sugar Foods Linked To Vision Loss
A recent study by Tufts nutrition researchers found that the development of age-related macular degeneration may be tied to over consumption of certain carbohydrates.