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Nirupa Matthan, Ph.D.

Nirupa Matthan Scientist II
Cardiovascular Nutrition Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3114
Fax: (617) 556-3103
E-mail: nirupa.matthan@tufts.edu
Education Ph.D., Nutritional Biochemistry
School of Dietetics and Human Nutrition, McGill University, Canada
Research Focus Dietary fatty acids, cholesterol metabolism, plant sterols, lipoproteins, kinetic modeling, nutrition and cardiovascular disease risk
Academic Appointments Assistant Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University
Selected Professional Affiliations

American Heart Association
American Society for Nutrition


Featured HNRCA Research Publications

Matthan NR, Jalbert SM, Ausman LM, Kuvin JT, Karas RH, Lichtenstein AH. Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subjects. Am J Clin Nutr. 2007;85(4):960-6.

Matthan NR, Jordan HS, Chung M, Lichtenstein AH, Lathrop D and Lau J. A systematic review and meta-analysis of the impact of omega-3 fatty acids on selected arrhythmia outcomes in animal models. Metabolism. 2005;54:1557-1565.

Matthan NR and Lichtenstein AH. Approaches to measuring cholesterol absorption in humans. Atherosclerosis. 2004;174:197-205.

Matthan NR, Welty FK, Barrett PHR, Harausz C, Dolnikowski GG, Parks JS, Eckel RH, Schaefer EJ and Lichtenstein AH. Dietary hydrogenated fat increases HDL apoA-1 catabolism and decreases LDL apoB-100 catabolism in hyper-cholesterolemic women. Atherosclerosis, Thrombosis and Vascular Biology. 2004;24:1092-1097

Matthan NR, Giovanni A, Schaefer EJ, Brown GB and Lichtenstein AH. Impact of simvastatin, niacin and/or antioxidants on cholesterol metabolism in CAD patients with low HDL. Journal of Lipid Research. 2003;44:800-806.

Other Recent Publications

Lamon-Fava S, Diffenderfer MR, Barrett PH, Buchsbaum A, Matthan NR, Lichtenstein AH, Dolnikowski GG, Horvath K, Asztalos BF, Zago V, Schaefer EJ. Effects of different doses of atorvastatin on human apolipoprotein B-100, B-48,and A-I metabolism. J Lipid Res. 2007;48(8):1746-53.

Erkkila AT, Matthan NR, Herrington DM, Lichtenstein AH. Higher plasma docosahexaenoic acid is associated with reduced progression of coronary atherosclerosis in women with CAD. J Lipid Res. 2006;47(12):2814-9.

Lichtenstein AH, Matthan NR, Jalbert SM, Resteghini NA, Schaefer EJ, Ausman LM. Novel soybean oils with different fatty acid profiles alter cardiovascular disease risk factors in moderately hyperlipidemic subjects. Am J Clin Nutr. 2006;84(3):497-504.

Matthan NR, Jalbert SM, Lamon-Fava S, Dolnikowski GG, Welty FK, Barrett HR, Schaefer EJ, Lichtenstein AH. TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a
function of age and menopausal status.
Arterioscler Thromb Vasc Biol. 2005;25(8):1691-6.

Jordan H, Matthan N, Chung M, Balk E, Chew P, Kupelnick B, DeVine D, Lawrence A, Lichtenstein A, Lau J. Effects of omega-3 fatty acids on arrhythmogenic mechanisms in animal and isolated organ/cell culture studies. Evid Rep Technol Assess (Summ). 2004;(92):1-8.

Matthan NR, Cianflone K, Lichtenstein AH, Ausman LM, Jauhiainen M, Jones PJ. Hydrogenated fat consumption affects acylation-stimulating protein levels and cholesterol esterification rates in moderately hypercholesterolemic women. J Lipid Res. 2001;42(11):1841-8.

Matthan NR, Raeini-Sarjaz M, Lichtenstein AH, Ausman LM, Jones PJ.
Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women. Lipids. 2000;35(9):1037-44.

Matthan NR, Ausman LM, Lichtenstein AH, Jones PJ. Hydrogenated fat consumption affects cholesterol synthesis in moderately
hypercholesterolemic women.
J Lipid Res. 2000;41(5):834-9.

Matthan NR, Jones PJ. Differential effects of individual trans fatty acid isomers on lipoprotein assembly and metabolism.
Nutr Rev. 1999;57(9 Pt 1):282-4.

To see more of Dr. Nirupa Matthan's publications, please visit PubMed and search for "Matthan N."