NIH Chemical Genomics Center

Discovering the
Pathway Between
Chemistry and Biology

Welcome to the National Institutes of Health (NIH) Chemical Genomics Center (NCGC), a member of the Molecular Libraries Probe Production Center Network. This center has been established by the NIH to create a national resource in chemical probe development. The center uses the latest industrial-scale technologies to collect data that is useful for defining the cross-section between chemical space and biological activity. To learn more about our mission and operations, please spend some time visiting the links above.

>> Recent News

Dec 19, 2008 //
International public-private partnership offers new paradigm for medicinal chemistry [>> more]

Nov 25, 2008 //
Chemical Genomics Screen Uncovers Clues to Fat Storage [>> more]

Sep 2, 2008 //
NCGC is now a member of the Molecular Libraries Probe Production Network [>> more]

Apr 28, 2008 //
Research Findings Open New Front in Fight against AIDS Virus [>> more]

Mar 16, 2008 //
Scientists Identify New Leads for Treating Parasitic Worm Disease [>> more]

Feb 14, 2008 //
NIH Collaborates with EPA to Improve the Safety Testing of Chemicals [>> more]

>> Recent Publication

Dec, 2008 //
Beller JA, et al in PLoS Biology. COPI Complex Is a Regulator of Lipid Homeostasis [>> more]

July, 2008 //
Auld DS, et al in ACS Chemical Biology. A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays [>> more]

April, 2008 //
Readinger JA, et al in PNAS. Selective targeting of ITK blocks multiple steps of HIV replication [>> more]

March, 2008 //
Sayed AA, Simeonov A, et al in Nature Medicine. Identification of oxadiazoles as new drug leads for the control of schistosomiasis [>> more]

>> Assay Guidance Manual

Version 5.0 //
The Latest Version of the Assay Guidance Manual Provides a Wealth of Resources [>> more]