Natalia A. Crivello, Ph.D.

Featured HNRCA Research Publications
	Scientist II Nutrition and Neurocognition Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3147 Fax: (617) 556-3243 E-mail: natalia.crivello@tufts.edu
Education	Ph.D., Biology Sechenov's Institute of the Russian Academy of Sciences
Research Focus	The interrelation between nutritional factors and age-related decline in motor and cognitive behavior, and lipid metabolism.
Academic Appointments	Assistant Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Crivello NA, Rosenberg IH, Shukitt-Hale B, Bielinski D, Dallal GE, Joseph JA. Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide. American Aging Association. 2007;29:191-203. Crivello NA, Rosenberg IH, Dallal GE, Bielinski D, Joseph JA. Age-related changes in neutral sphingomyelin-specific phospholipase C activity in striatum, hippocampus, and frontal cortex: implication for sensitivity to stress and inflammation. Neurochemistry International. 2005;47(8):573-9. Denisova NA, Booth SL. Vitamin K and Sphingolipid Metabolism: Evidence to Date. Nutritional Reviews. 2005;63:111-21. Denisova NA, Shukitt-Hale B, Rabin BM, Joseph JA. Brain signaling and behavioral responses induced by exposure to Fe-56-particle radiation. Radiation Research. 2002;158(6):725-34. Hassan WN, Cantuti-Castelvetri I, Denisova NA, Joseph JA, Paulson KE. The nitrone spin trap PBN alters the cellular response to H2O2: activation of the EGF receptor/ERK pathway. Free Radical Biology and Medicine. 2002;32(6):551-61.
Other Recent Publications Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, Morgan D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci. 2003;6(3):153-62. Denisova NA, Cantuti-Castelvetri I, Hassan WN, Paulson KE, Joseph JA. Role of membrane lipids in regulation of vulnerability to oxidative stress in PC12 cells: implication for aging. Free Radic Biol Med. 2001;30(6):671-8. Joseph J, Shukitt-Hale B, Denisova NA, Martin A, Perry G, Smith MA. Copernicus revisited: amyloid beta in Alzheimer's disease. Neurobiol Aging. 2001;22(1):131-46. Joseph JA, Denisova NA, Bielinski D, Fisher DR, Shukitt-Hale B. Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention. Mech Ageing Dev. 2000;116(2-3):141-53. Denisova NA, Fisher D, Provost M, Joseph JA. The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium "dysregulation" in PC12 cells. Free Radic Biol Med. 1999;27(11-12):1292-301. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, Bickford PC. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci. 1999;19(18):8114-21. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, Bickford PC. Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J Neurosci. 1998;18(19):8047-55. Denisova NA, Strain JG, Joseph JA. Oxidant injury in PC12 cells--a possible model of calcium "dysregulation" in aging: II. Interactions with membrane lipids. J Neurochem. 1997;69(3):1259-66. Shukitt-Hale B, Denisova NA, Strain JG, Joseph JA. Psychomotor effects of dopamine infusion under decreased glutathione conditions. Free Radic Biol Med. 1997;23(3):412-8. Joseph JA, Villalobos-Molinas R, Denisova NA, Erat S, Strain J. Cholesterol: a two-edged sword in brain aging. Free Radic Biol Med. 1997;22(3):455-62. To see more of Dr. Natalia Crivello's publications, please visit PubMed and search for "Crivello NA" or "Denisova NA."