Robert M. Russell, M.D.

A Life in Nutrition: Robert Russell to step down as HNRCA director

Featured HNRCA Research Publications
	Senior Scientist and Director Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3335 Fax: (617) 556-3295 E-mail: rob.russell@tufts.edu
Education	M.D., Columbia University
Research Focus	Retinoids, carotenoids, aging, gastrointestinal function
Academic Appointments	Professor, Nutrition, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University Professor, Medicine, Tufts University School of Medicine
Selected Professional Affiliations	Editor, Nutrition Reviews Associate Editor, American Journal of Clinical Nutrition
Board Certification	Internal Medicine Gastroenterology
For more information on Dr. Robert Russell, please visit the USDA, Agricultural Research Service .
Kim, Y., Chongviriyaphan, N., Liu, C., Russell, R.M., Wang, X. Combined antioxidanta (beta-carotene, alpha-tocopherol and asorbic acid) supplementation incresase the levels of lung retinoic acid inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model. Carcinogenesis. 2006;27(7):1410-9. Lian, F., Smith, D., Ernst, H., Russell, R.M., Wang, X. Apo-10'-lycopenoic acid suppresses lung cancer cell growth by activating retinoic acid receptor Beta in vitro, and inhibits lung tumorigenesis in vivo in the A/J mouse model. Carcinogenesis. 2007;28:1567-1574. Hu, K., Liu, C., Ernst, H., Krinsky, N.I., Russell, R.M., Wang, X. The biochemical characterization of ferret carotene-9', 10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo. Journal of Biological Chemistry. 2006;281:19327-19338. Wang, Z., Yin, S., Zhao, X., Russell, R.M., Tang, G. Beta-carotene-vitamin a equivalence in chinese adults assessed by an isotope dilution technique. British Journal of Nutrition. 2004;91(1):121-31. Liu, C., Russell, R.M., Wang, X. Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lung via induction of cytochrome P450 enzymes. Journal of Nutrition. 2003;133: 173-9.
Other Recent Publications Ferreira AL, Yeum KJ, Matsubara LS, Matsubara BB, Correa CR, Pereira EJ, Russell RM, Krinsky NI, Tang G. Doxorubicin as an antioxidant: maintenance of myocardial levels of lycopene under doxorubicin treatment. Free Radic Biol Med. 2007;43(5):740-51. Anjos Ferreira AL, Russell RM, Rocha N, Placido Ladeira MS, Favero Salvadori DM, Oliveira Nascimento MC, Matsui M, Carvalho FA, Tang G, Matsubara LS, Matsubara BB. Effect of lycopene on Doxorubicin-induced cardiotoxicity: an echocardiographic, histological and morphometrical assessment. Basic Clin Pharmacol Toxicol. 2007;101(1):16-24. Russell RM, Sharp FC, Rasko DA, Sperandio V. QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli. J Bacteriol. 2007;189(14):5387-92. Kim Y, Lian F, Yeum KJ, Chongviriyaphan N, Choi SW, Russell RM, Wang XD. The effects of combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation on antioxidant capacity, DNA single-strand breaks and levels of insulin-like growth factor-1/IGF-binding protein 3 in the ferret model of lung cancer. Int J Cancer. 2007;120(9):1847-54. Mernitz H, Smith DE, Wood RJ, Russell RM, Wang XD. Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity. Int J Cancer. 2007;120(7):1402-9. Lian F, Hu KQ, Russell RM, Wang XD. Beta-cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor beta expression. Int J Cancer. 2006;119(9):2084-9. Russell RM. The multifunctional carotenoids: insights into their behavior. J Nutr.2006;136(10):2690S-2S. Beretta G, Aldini G, Facino RM, Russell RM, Krinsky NI, Yeum KJ. Total antioxidant performance: a validated fluorescence assay for the measurement of plasma oxidizability. Anal Biochem. 2006;354(2):290-8. Kim Y, Liu XS, Liu C, Smith DE, Russell RM, Wang XD. Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): a model for human lung cancer. Cancer Lett. 2006;234(2):209-19. Zhao X, Aldini G, Johnson EJ, Rasmussen H, Kraemer K, Woolf H, Musaeus N, Krinsky NI, Russell RM, Yeum KJ. Modification of lymphocyte DNA damage by carotenoid supplementation in postmenopausal women. Am J Clin Nutr. 2006;83(1):163-9. To see more of Dr. Robert M. Russell's publications, please visit PubMed and search for "Russell RM."