Publications

Lian F, and Wang X-D.  Apo-10’-lycopenoic acid induces Nrf2-mediated expression of phase II detoxification and antioxidant enzymes in human bronchial epithelial cells. International Journal of Cancer. 2008; 123: 1262-1268.

Veeramachaneni S, Ausman LM, Choi SW, Russell RM and Wang X-D.  High dose lycopene supplementation increases hepatic CYP2E1 protein and inflammation in alcohol fed rats. J Nutr. 2008; 138: 1329-1335.

Lee CW, Wang X-D, Chien KL, Ge Z, Rickman BH, Rogers AB, Varro A, Whary MT, Wang TC, and Fox JG.  Vitamin C supplementation does not protect L-gulono-beta-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy. International Journal of Cancer. 2008; 122: 1068-1076.

Wang Y, Ausman LM, Russell RM, Greenberg AS and Wang X-D.  Increased apoptosis in high-fat diet induced nonalcoholic steatohepatitis is associated with c-Jun NH₂-terminal kinase activation and elevated pro-apoptotic Bax in rats. J Nutr; 2008 (in press).

Lian F, Smith D, Ernst H, Russell RM, Wang X-D. Lycopene metabolites, apo-10'-lycopenoic acid, inhibits the growth of lung cancer cells in vitro and suppresses lung carcinogenesis in A/J mice in vivo. Carcinogenesis. 2007; 28: 1567-1574.

Mernitz H, Smith D, Wood R, Russell RM, and Wang X-D. Inhibition of Lung Carcinogenesis by 1alpha,25-Dihydroxyvitamin D3 and 9-cis Retinoic Acid in the A/J Mouse Model: Evidence of Retinoid Antagonism of Vitamin D Toxicity. International Journal of Cancer. 2007; 120: 1402-1409.

Kim Y, Lian F, Yeum KJ, Russell RM, and Wang X-D. The Effects of Combined Antioxidant (beta-Carotene, alpha-Tocopherol and Ascorbic acid) Supplementation on Antioxidant Capacity, DNA Single-Strand Break and Regulation of Insulin Growth Factor-1/IGF-Binding Protein 3 in Ferret Model of Lung Cancer. International Journal of Cancer. 2007; 120: 1847-1854.

Mernitz H and Wang X-D. The bioconversion of carotenoids into retinoids: Implications for cancer prevention.In: "Vitamin A: New Research." Ed. Loessing, I. T. Hauppauge, NY: Nova Science Publisher, Inc. Press, 2007:1-19.

Hu KQ, Liu C, Ernst H, Krinsky NI, Russell RM and Wang X-D. The Biochemical Characterization of Ferret Carotene-9', 10'-Monooxygenase Catalyzing Cleavage of Carotenoids in vitro and in vivo. J Bio Chem. 2006; 281(28):19327-19338.

Kim Y, Liu XL, Liu C, Smith DE, Russell RM, Wang X-D. Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone: A model for human lung cancer. Cancer Letters. 2006; 234: 209-219.

Taparia S, Fleet JC, Peng JB, Wang X-D, Wood RJ. 1,25-Dihydroxyvitamin D and 25-Hydroxyvitamin D-mediated Regulation of TRPV6 (a putative epithelial calcium channel) mRNA Expression in Caco-2 Cells. Eur J Nutr. 2006; 45: 196-204.

Liu C, Russell RM, Wang X-D. Lycopene supplementation prevents smoke-induced changes in p53, p53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets. J Nutr. 2006; 136: 106-111.

Kim Y, Chongyviriyaphan N, Liu C, Russell RM, Wang X-D. Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model. Carcinogenesis. 2006; 27: 1410-1419.

Lian F, Hu KQ, Russell RM, Wang X-D. Beta-Cryptoxanthin inhibits the growth of immortalized human bronchia epithelial cells and non-small cell lung cancer cells and up-regulates retinoic acid receptor Beta expression. International J Cancer. 2006; 119: 2084-2089.

Mernitz H, Smith D, Zhu AX, Wang X-D. Effects of 9-cis retinoic acid supplementation on COX-2 and RAR beta levels and tumor formation in the lungs of NNK-induced A/J mice. Cancer Letters. 2006; 244: 101-108.