=> DATA FILE SET-LEVEL: JALSSA03
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Description:
The JALSSA03 data file set consists of three analytic files, prepared in connection with the 1950-1990 cancer incidence Life Span Study (LSS) of the Radiation Effects Research Foundation (RERF) by DA Pierce, et al., on atomic bomb survivors in Japan.
The JALSSA01 data file set (LSS Mortality Report 11, 1987) was updated and replaced by JALSSA03 (LSS Mortality Report 12, 1996). Apart from differences in the organization of the data, JALSSA03 duplicates and contains all the data in JALSSA01.
Also, JALSSA01 and JALSSA03 are partly duplicated by JALSSA02, which contains data on cancer incidence rather than mortality. Data files JALSSA02/DS86ADJF and JALSSA03/DS86ADJF are identical to each other, and similar to JALSSA01/NEAREXP.
Some of the differences among JALSSA01, JALSSA02, and JALSSA03 are summarized in "Notes on RERF Data in CEDR".
The RERF data file sets JALSSA01, JALSSA02 and JALSSA03 differ from many CEDR data file sets in that they do not present mortality information on individuals, but rather a cross-tabulation of death counts (or cancer cases) and person years over stratifying variables.
Data file set JALSSA03:
The data in data file set JALSSA03 were released by RERF in September 1996, in conjunction with the publication of Report 12 Part 1, on cancer mortality in the Life Span Study cohort of atomic bomb survivors. The paper by Pierce et al. (Ref.1 under Citations) presents the results of some of RERF's analyses of these data.
The three data files in CEDR data file set JALSSA03 include:
R12CANC: detailed person year table with data on all major cancer sites
R12LEUK: detailed person year table with data on leukemia and other hematopoietic cancers
DS86ADJF: adjustment factors that can be used to convert colon doses to approximate doses for other organs. This file is identical to the file DS86ADJF in CEDR data file set JALSSA02.
In the RERF analyses, separate person-year tabulations were made for each organ dose. The solid cancer table (file R12CANC) was defined using colon dose. In order to allow one to carry out analyses based on doses to other organs, the file DS86ADJF includes a table of city-specific and age-at-exposure-specific organ dose adjustment factors. The leukemia, lymphoma, and myeloma cancer table (file R12LEUK) was defined using bone marrow dose.
The solid cancer and leukemia data sets, R12CANC and R12LEUK, are detailed tabulations of person years, case counts, and summary data constructed from data on individual survivors. The cohort for analysis includes 86,572 survivors. This total includes all survivors, including those with DS86 shielded kerma estimates greater than 4 Gy. The data sets are structured to make it easy to exclude survivors with total shielded kerma estimates above 4 Gy, as was done for some of the Report 12 analyses.
Data on individual survivors were stratified on city, sex, age at exposure, attained age, calendar time, and dose to produce these data sets. Dose categories in the leukemia data set are defined in terms of total weighted bone marrow dose, while dose categories in the solid cancer table are defined using weighted dose to the colon. These weighted doses were computed as the gamma dose plus ten times the neutron dose.
Other site-specific analyses in Report 12 were based on data sets of the same basic form, in which the data were grouped by the appropriate organ dose. It is impractical to distribute all of these data sets. However, as noted above, the file DS86ADJF contains city- and age-at-exposure-specific conversion factors that can be used to compute estimates of doses to other organs. A command script distributed by RERF provides an explicit illustration of how one can use these factors to compute doses for other organs.
If these data are used as the basis for analyses in any publication including working papers or technical reports, a statement of acknowledgment must be included in the manuscript. This statement should read:
"This report makes use of data obtained from the Radiation Effects Research Foundation (RERF) in Hiroshima, Japan. RERF is a private foundation funded equally by the Japanese Ministry of Health and Welfare and the U.S. Department of Energy through the U.S. National Academy of Sciences. The conclusions in this report are those of the authors and do not necessarily reflect the scientific judgment of RERF or its funding agencies."
Please send a copy of any manuscripts which make use of these data to: Editorial Office, Radiation Effects Research Foundation, 5-2 Hijiyama Koen, Minami-ku, Hiroshima Shi 732 JAPAN
Number of data files: 3
Cohort Size: 86572
Providing Organization: Radiation Effects Research Foundation (RERF)
Creating Organization: Radiation Effects Research Foundation (RERF)
Originating Organization: Radiation Effects Research Foundation (RERF)
Races: Japanese
Sexes: male$ female
Diseases: solid cancer mortality$ leukemia mortality
Earliest Exposure: 08/15/1945
Latest Exposure: 08/15/1945
Follow-Up: 12/31/1990
Exposure Type: exposure to atomic bomb blast$ subsequent exposure to radioactive fallout
Exposure Agent: neutron$ gamma
Method: See reference 1.
Sites: Japan
Notes: Please see Notes on JALSSA03.
Derivation: See abstracts under Citations.
Contact Information:
Maruyama, Fumie
Radiation Effects Research Foundation