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Acetylcholine esterase inhibitor Chloride channel activators Compounds of unknown or non-specific mode of action (mite growth inhibitors) Compounds of unknown or uncertain mode of action Ecdysone agonists / moulting disruptors GABA-gated chloride channel antagonists Inhibitors of acetyl CoA carboxylase - Lipid synthesis, growth regulation Inhibitors of chitin biosynthesis, type 0, Lepidopteran Inhibitors of chitin biosynthesis, type 1, Homopteran Inhibitors of mitochondrial ATP synthase Juvenile hormone mimics Microbial disruptors of insect midgut membranes (includes transgenic crops expressing B.t. toxins) Miscellaneous nonspecific (multi-site) inhibitors Mitochondrial complex I electron transport inhibitors Mitochondrial complex III electron transport inhibitors (Coupling site II) Mitochondrial complex IV electron transport inhibitors Moulting disruptor, Dipteran Nicotinic Acetylcholine receptor agonists Nicotinic Acetylcholine receptor allosteric activators Nicotinic acetylcholine receptor channel blockers Octopaminergic receptor agonists Ryanodine receptor modulators Selective homopteran feeding blockers Sodium channel modulators Uncouplers of oxidative phosphorylation via disruption of proton gradient Vacant Vacant Vacant Voltage-dependent sodium channel blockers
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Alky halides Avermectins, Milbemycins Benzoylureas Carbamates Cyclodiene organochlorines DDT, Methoxychlor Diacylhydrazines Diamides Juvenile hormone analogues METI acaricides Neonicotinoids Nereistoxin analogues Nicotine Organophosphates Organotin miticides Phenylpyrazoles (Fiproles) Pyrethroids, Pyrethrins Spinosyns Tetronic and Tetramic acid derivatives
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(none) Abamectin Acephate Acequinocyl Acetamiprid Acrinathrin Alanycarb Aldicarb Allethrin Aluminium phosphide Amitraz Azadirachtin Azamethiphos Azinphos-ethyl Azinphos-methyl Azocyclotin B.t. var. aizawai B.t. var. israelensis B.t. var. kurstaki B.t. var. sphaericus B.t. var. tenebrionensis Bendiocarb Benfuracarb Bensultap Benzoximate Bifenazate Bifenthrin Bioallethrin Bioallethrin S-cyclopentenyl Bioresmethrin Bistrifluron Bt crop proteins: Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1 Buprofezin Butocarboxim Butoxycarboxim Cadusafos Calcium phosphide Carbaryl Carbofuran Carbosulfan Cartap hydrochloride Chinomethionat Chlorantraniliprole Chlordane Chlorethoxyfos Chlorfenapyr Chlorfenvinphos Chlorfluazuron Chlormephos Chloropicrin Chlorpyrifos Chlorpyrifos-methyl Chromafenozide Clofentezine Clothianidin Coumaphos Cryolite Cyanide Cyanophos Cycloprothrin Cyfluthrin Cyhalothrin Cyhexatin Cypermethrin Cyphenothrin [(1R)-trans- isomers] Cyromazine DDT DNOC Deltamethrin Demeton-S-methyl Diafenthiuron Diazinon Dichlorvos/ DDVP Dicofol Dicrotophos Diflubenzuron Dimethoate Dimethylvinphos Dinotefuran Disulfoton EPN Emamectin benzoate Empenthrin [(EZ)- (1R)- isomers] Endosulfan Esfenvalerate Ethiofencarb Ethion Ethiprole Ethoprophos Etofenprox Etoxazole Famphur Fenamiphos Fenazaquin Fenbutatin oxide Fenitrothion Fenobucarb Fenoxycarb Fenpropathrin Fenpyroximate Fenthion Fenvalerate Fipronil Flonicamid Fluacrypyrim Flubendiamide Flucycloxuron Flucythrinate Flufenoxuron Flumethrin Fonofos Formetanate Fosthiazate Furathiocarb Halfenprox Halofenozide Heptenophos Hexaflumuron Hexythiazox Hydramethylnon Hydroprene Imidacloprid Imiprothrin Indoxacarb Isofenphos Isoprocarb Isopropyl O-(methoxyaminothio-phosphoryl)salicylate Isoxathion Kinoprene Lufenuron Malathion Mecarbam Metaflumizone Methamidophos Methidathion Methiocarb Methomyl Methoprene Methoxychlor Methoxyfenozide Methyl bromide and other alkyl halides Metolcarb Mevinphos Milbemectin Monocrotophos Naled Nicotine Nitenpyram Novaluron Noviflumuron Omethoate Oxamyl Oxydemeton-methyl Parathion Parathion-methyl Permethrin Phenothrin [(1R)-trans- isomer] Phenthoate Phorate Phosalone Phosmet Phosphamidon Phosphine Phoxim Pirimicarb Pirimiphos-ethyl Prallethrin Profenofos Propaphos Propargite Propetamphos Propoxur Prothiofos Pymetrozine Pyraclofos Pyridaben Pyridalyl Pyridaphenthion Pyrimidifen Pyriproxyfen Quinalphos RU 15525 Resmethrin Rotenone Silafluofen Spinetoram Spinosad Spirodiclofen Spiromesifen Spirotetramat Sulfotep Sulfuryl fluoride Tartar emetic Tebufenozide Tebufenpyrad Tebupirimfos Teflubenzuron Tefluthrin Temephos Terbufos Tetrachlorvinphos Tetradifon Tetramethrin Tetramethrin [(1R)- isomers] Thiacloprid Thiamethoxam Thiocyclam Thiodicarb Thiofanox Thiometon Thiosultap-sodium Tolfenpyrad Tralomethrin Transfluthrin Triazamate Triazophos Trichlorfon Triflumuron Trimethacarb Vamidothion XMC Xylylcarb ZXI 8901 Zinc phosphide alpha-Cypermethrin beta-Cyfluthrin beta-Cypermethrin d-cis-trans Allethrin d-trans Allethrin gamma-Cyhalothrin lambda-Cyhalothrin tau-Fluvalinate theta-Cypermethrin zeta-Cypermethrin
1 - Acetylcholine esterase inhibitor Subgroup: A Chemical Class: Carbamates Aldicarb Alanycarb Bendiocarb Benfuracarb Butocarboxim Butoxycarboxim Carbaryl Carbofuran Carbosulfan Ethiofencarb Fenobucarb Formetanate Furathiocarb Isoprocarb Methiocarb Methomyl Metolcarb Oxamyl Pirimicarb Propoxur Thiodicarb Thiofanox Triazamate Trimethacarb XMC Xylylcarb
Subgroup: B Chemical Class: Organophosphates Acephate Azamethiphos Azinphos-ethyl Azinphos-methyl Cadusafos Chlorethoxyfos Chlorfenvinphos Chlormephos Chlorpyrifos Chlorpyrifos-methyl Coumaphos Cyanophos Demeton-S-methyl Diazinon Dichlorvos/ DDVP Dicrotophos Dimethoate Dimethylvinphos Disulfoton EPN Ethion Ethoprophos Famphur Fenamiphos Fenitrothion Fenthion Fonofos Fosthiazate Heptenophos Isofenphos Isopropyl O-(methoxyaminothio-phosphoryl)salicylate Isoxathion Malathion Mecarbam Methamidophos Methidathion Mevinphos Monocrotophos Naled Omethoate Oxydemeton-methyl Parathion Parathion-methyl Phenthoate Phorate Phosalone Phosmet Phosphamidon Phoxim Pirimiphos-ethyl Profenofos Propaphos Propetamphos Prothiofos Pyraclofos Pyridaphenthion Quinalphos Sulfotep Tebupirimfos Temephos Terbufos Tetrachlorvinphos Thiometon Triazophos Trichlorfon Vamidothion
2 - GABA-gated chloride channel antagonists Subgroup: A Chemical Class: Cyclodiene organochlorines Chlordane Endosulfan
Subgroup: B Chemical Class: Phenylpyrazoles (Fiproles) Ethiprole Fipronil
3 - Sodium channel modulators Subgroup: A Chemical Class: Pyrethroids, Pyrethrins Acrinathrin Allethrin d-cis-trans Allethrin d-trans Allethrin Bifenthrin Bioallethrin Bioallethrin S-cyclopentenyl Bioresmethrin Cycloprothrin Cyfluthrin beta-Cyfluthrin Cyhalothrin lambda-Cyhalothrin gamma-Cyhalothrin Cypermethrin alpha-Cypermethrin beta-Cypermethrin theta-Cypermethrin zeta-Cypermethrin Cyphenothrin [(1R)-trans- isomers] Deltamethrin Empenthrin [(EZ)- (1R)- isomers] Esfenvalerate Etofenprox Fenpropathrin Fenvalerate Flucythrinate Flumethrin tau-Fluvalinate Halfenprox Imiprothrin Permethrin Phenothrin [(1R)-trans- isomer] Prallethrin Resmethrin RU 15525 Silafluofen Tefluthrin Tetramethrin Tetramethrin [(1R)- isomers] Tralomethrin Transfluthrin ZXI 8901
Chemical Class: DDT, Methoxychlor DDT Methoxychlor
4 - Nicotinic Acetylcholine receptor agonists Subgroup: A Chemical Class: Neonicotinoids Acetamiprid Clothianidin Dinotefuran Imidacloprid Nitenpyram Thiacloprid Thiamethoxam
Subgroup: B Chemical Class: Nicotine Nicotine
5 - Nicotinic Acetylcholine receptor allosteric activators Subgroup: (none) Chemical Class: Spinosyns Spinetoram Spinosad
6 - Chloride channel activators Subgroup: (none) Chemical Class: Avermectins, Milbemycins Abamectin Emamectin benzoate Milbemectin
7 - Juvenile hormone mimics Subgroup: A Chemical Class: Juvenile hormone analogues Hydroprene Kinoprene Methoprene
Subgroup: B Chemical Class: (none) Fenoxycarb
Subgroup: C Chemical Class: (none) Pyriproxyfen
8 - Miscellaneous nonspecific (multi-site) inhibitors Subgroup: A Chemical Class: Alky halides Methyl bromide and other alkyl halides
Subgroup: B Chemical Class: (none) Chloropicrin
Subgroup: C Chemical Class: (none) Sulfuryl fluoride
Subgroup: D Subgroup: E Chemical Class: (none) Tartar emetic
9 - Selective homopteran feeding blockers Subgroup: B Chemical Class: (none) Pymetrozine
Subgroup: C Chemical Class: (none) Flonicamid
10 - Compounds of unknown or non-specific mode of action (mite growth inhibitors) Subgroup: A Chemical Class: (none) Clofentezine Hexythiazox
Subgroup: B Chemical Class: (none) Etoxazole
11 - Microbial disruptors of insect midgut membranes (includes transgenic crops expressing B.t. toxins) Subgroup: (none) Chemical Class: (none) B.t. var. israelensis B.t. var. sphaericus B.t. var. aizawai B.t. var. kurstaki B.t. var. tenebrionensis Bt crop proteins: Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1
12 - Inhibitors of mitochondrial ATP synthase Subgroup: A Chemical Class: (none) Diafenthiuron
Subgroup: B Chemical Class: Organotin miticides Azocyclotin Cyhexatin Fenbutatin oxide
Subgroup: C Chemical Class: (none) Propargite
Subgroup: D Chemical Class: (none) Tetradifon
13 - Uncouplers of oxidative phosphorylation via disruption of proton gradient Subgroup: (none) Chemical Class: (none) Chlorfenapyr
Chemical Class: (none) DNOC
14 - Nicotinic acetylcholine receptor channel blockers Subgroup: (none) Chemical Class: Nereistoxin analogues Bensultap Cartap hydrochloride Thiocyclam Thiosultap-sodium
15 - Inhibitors of chitin biosynthesis, type 0, Lepidopteran Subgroup: (none) Chemical Class: Benzoylureas Bistrifluron Chlorfluazuron Diflubenzuron Flucycloxuron Flufenoxuron Hexaflumuron Lufenuron Novaluron Noviflumuron Teflubenzuron Triflumuron
16 - Inhibitors of chitin biosynthesis, type 1, Homopteran Subgroup: (none) Chemical Class: (none) Buprofezin
17 - Moulting disruptor, Dipteran Subgroup: (none) Chemical Class: (none) Cyromazine
18 - Ecdysone agonists / moulting disruptors Subgroup: (none) Chemical Class: Diacylhydrazines Chromafenozide Halofenozide Methoxyfenozide Tebufenozide
19 - Octopaminergic receptor agonists Subgroup: (none) Chemical Class: (none) Amitraz
20 - Mitochondrial complex III electron transport inhibitors (Coupling site II) Subgroup: A Chemical Class: (none) Hydramethylnon
Subgroup: B Chemical Class: (none) Acequinocyl
Subgroup: C Chemical Class: (none) Fluacrypyrim
21 - Mitochondrial complex I electron transport inhibitors Subgroup: A Chemical Class: METI acaricides Fenazaquin Fenpyroximate Pyrimidifen Pyridaben Tebufenpyrad Tolfenpyrad
Subgroup: B Chemical Class: (none) Rotenone
22 - Voltage-dependent sodium channel blockers Subgroup: A Chemical Class: (none) Indoxacarb
Subgroup: B Chemical Class: (none) Metaflumizone
23 - Inhibitors of acetyl CoA carboxylase - Lipid synthesis, growth regulation Subgroup: Tetronic and Tetramic acid derivatives Chemical Class: Tetronic and Tetramic acid derivatives Spirodiclofen Spiromesifen Spirotetramat
24 - Mitochondrial complex IV electron transport inhibitors Subgroup: A Chemical Class: (none) Aluminium phosphide Calcium phosphide Phosphine Zinc phosphide
Subgroup: B Chemical Class: (none) Cyanide
28 - Ryanodine receptor modulators Subgroup: (none) Chemical Class: Diamides Chlorantraniliprole Flubendiamide
UN - Compounds of unknown or uncertain mode of action Subgroup: (none) Chemical Class: (none) Azadirachtin
Subgroup: (none) Chemical Class: (none) Benzoximate
Subgroup: (none) Chemical Class: (none) Bifenazate
Subgroup: (none) Chemical Class: (none) Chinomethionat
Subgroup: (none) Chemical Class: (none) Cryolite
Subgroup: (none) Chemical Class: (none) Dicofol
Subgroup: (none) Chemical Class: (none) Pyridalyl