Developmental neurotoxicity is any effect of a toxicant on the developing nervous system before or after birth that interferes with normal nervous system structure or function. The developing nervous system is especially susceptible to perturbations because development of the brain continues into the postnatal period and limited cell regeneration occurs following damage leading to persistent effects. Many chemicals in our environment have not been tested for toxicity to the developing brain and nervous system. SBRP-funded researchers are conducting multidisciplinary research to develop cellular and molecular markers to serve as milestones to indicate the proper maturation of the nervous system. In combination with cognitive and behavioral testing, this research is leading to an increased understanding of the impact of pre-natal and peri-natal exposure to environmental contaminants.
Use the search tools below to find additional information about SBRP-funded research projects addressing the developmental neurotoxicity of environmental contaminants.