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NCI-Nature curated

Pathway Source
Alpha-synuclein signaling NCI-Nature curated
Alternative NF-kappaB pathway NCI-Nature curated
Angiopoietin receptor Tie2-mediated signaling NCI-Nature curated
Arf1 pathway NCI-Nature curated
Arf6 signaling events NCI-Nature curated
    Subnetwork: Arf6 downstream pathway
NCI-Nature curated
    Subnetwork: Arf6 mediated densensitization of LHCGR
NCI-Nature curated
    Subnetwork: Arf6 trafficking events
NCI-Nature curated
Atypical NF-kappaB pathway NCI-Nature curated
BARD1 signaling events NCI-Nature curated
BCR signaling pathway NCI-Nature curated
BMP receptor signaling NCI-Nature curated
Canonical NF-kappaB pathway NCI-Nature curated
Caspase cascade in apoptosis NCI-Nature curated
Cellular roles of Anthrax toxin NCI-Nature curated
Ceramide signaling pathway NCI-Nature curated
Circadian rhythm pathway NCI-Nature curated
Class I PI3K signaling events NCI-Nature curated
    Subnetwork: Class I PI3K signaling events mediated by Akt
NCI-Nature curated
    Subnetwork: Class IB PI3K non-lipid kinase events
NCI-Nature curated
EPO signaling pathway NCI-Nature curated
Effects of Botulinum toxin NCI-Nature curated
Endothelins NCI-Nature curated
EphrinA-EPHA pathway NCI-Nature curated
    Subnetwork: EPHA forward signaling
NCI-Nature curated
    Subnetwork: EPHA2 forward signaling
NCI-Nature curated
    Subnetwork: Ephrin A reverse signaling
NCI-Nature curated
EphrinB-EPHB pathway NCI-Nature curated
    Subnetwork: EPHB forward signaling
NCI-Nature curated
    Subnetwork: Ephrin B reverse signaling
NCI-Nature curated
FAS signaling pathway (CD95) NCI-Nature curated
FGF signaling pathway NCI-Nature curated
FOXA transcription factor networks NCI-Nature curated
    Subnetwork: FOXA1 transcription factor network
NCI-Nature curated
    Subnetwork: FOXA2 and FOXA3 transcription factor networks
NCI-Nature curated
FOXM1 transcription factor network NCI-Nature curated
Fc-epsilon receptor I signaling in mast cells NCI-Nature curated
FoxO family signaling NCI-Nature curated
Glypican pathway NCI-Nature curated
    Subnetwork: Glypican 1 network
NCI-Nature curated
    Subnetwork: Glypican 2 network
NCI-Nature curated
    Subnetwork: Glypican 3 network
NCI-Nature curated
HIV-1 Nef: Negative effector of Fas and TNF-alpha NCI-Nature curated
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha NCI-Nature curated
    Subnetwork: HIF-1-alpha transcription factor network
NCI-Nature curated
IFN-gamma pathway NCI-Nature curated
IGF1 pathway NCI-Nature curated
IL1-mediated signaling events NCI-Nature curated
    Subnetwork: Regulation of p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: Signaling mediated by p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: p38 signaling mediated by MAPKAP kinases
NCI-Nature curated
IL12-mediated signaling events NCI-Nature curated
    Subnetwork: IL12 signaling mediated by STAT4
NCI-Nature curated
IL2-mediated signaling events NCI-Nature curated
    Subnetwork: IL2 signaling events mediated by PI3K
NCI-Nature curated
    Subnetwork: IL2 signaling events mediated by STAT5
NCI-Nature curated
IL23-mediated signaling events NCI-Nature curated
IL27-mediated signaling events NCI-Nature curated
IL4-mediated signaling events NCI-Nature curated
IL6-mediated signaling events NCI-Nature curated
Insulin Pathway NCI-Nature curated
    Subnetwork: Insulin-mediated glucose transport
NCI-Nature curated
Integrins in angiogenesis NCI-Nature curated
    Subnetwork: Osteopontin-mediated events
NCI-Nature curated
LPA receptor mediated events NCI-Nature curated
    Subnetwork: LPA4-mediated signaling events
NCI-Nature curated
Lissencephaly gene (LIS1) in neuronal migration and development NCI-Nature curated
Neurotrophic factor-mediated Trk receptor signaling NCI-Nature curated
    Subnetwork: Trk receptor signaling mediated by PI3K and PLC-gamma
NCI-Nature curated
    Subnetwork: Trk receptor signaling mediated by the MAPK pathway
NCI-Nature curated
PDGFR-alpha signaling pathway NCI-Nature curated
PDGFR-beta signaling pathway NCI-Nature curated
Plasma membrane estrogen receptor signaling NCI-Nature curated
    Subnetwork: Regulation of p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: Signaling mediated by p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: p38 signaling mediated by MAPKAP kinases
NCI-Nature curated
Presenilin action in Notch and Wnt signaling NCI-Nature curated
Proteogylcan syndecan-mediated signaling events NCI-Nature curated
    Subnetwork: Noncanonical Wnt signaling pathway
NCI-Nature curated
    Subnetwork: Syndecan-1-mediated signaling events
NCI-Nature curated
    Subnetwork: Syndecan-2-mediated signaling events
NCI-Nature curated
    Subnetwork: Syndecan-3-mediated signaling events
NCI-Nature curated
    Subnetwork: Syndecan-4-mediated signaling events
NCI-Nature curated
Reelin signaling pathway NCI-Nature curated
Regulation of Androgen receptor activity NCI-Nature curated
    Subnetwork: Coregulation of Androgen receptor activity
NCI-Nature curated
Regulation of Telomerase NCI-Nature curated
Regulation of cytoplasmic and nuclear SMAD2/3 signaling NCI-Nature curated
    Subnetwork: Regulation of nuclear SMAD2/3 signaling
NCI-Nature curated
Retinoic acid receptors-mediated signaling NCI-Nature curated
    Subnetwork: RXR and RAR hetrodimerization with other nuclear receptor
NCI-Nature curated
Role of Calcineurin-dependent NFAT signaling in lymphocytes NCI-Nature curated
    Subnetwork: Calcineurin-regulated NFAT-dependent transcription in lymphocytes
NCI-Nature curated
Signaling by Aurora kinases NCI-Nature curated
    Subnetwork: Aurora A signaling
NCI-Nature curated
    Subnetwork: Aurora B signaling
NCI-Nature curated
    Subnetwork: Aurora C signaling
NCI-Nature curated
Signaling events activated by Hepatocyte Growth Factor Receptor (c-Met) NCI-Nature curated
Signaling events mediated by HDAC Class I NCI-Nature curated
Signaling events mediated by HDAC Class II NCI-Nature curated
Signaling events mediated by HDAC Class III NCI-Nature curated
Signaling events mediated by PRL NCI-Nature curated
Signaling events mediated by PTP1B NCI-Nature curated
Signaling events mediated by Stem cell factor receptor (c-Kit) NCI-Nature curated
Signaling events mediated by VEGFR1 and VEGFR2 NCI-Nature curated
    Subnetwork: VEGFR1 specific signals
NCI-Nature curated
Signaling events mediated by the Hedgehog family NCI-Nature curated
    Subnetwork: Hedgehog signaling events mediated by Gli proteins
NCI-Nature curated
Signaling events regulated by Ret tyrosine kinase NCI-Nature curated
Sphingosine 1-phosphate (S1P) pathway NCI-Nature curated
    Subnetwork: S1P1 pathway
NCI-Nature curated
    Subnetwork: S1P2 pathway
NCI-Nature curated
    Subnetwork: S1P3 pathway
NCI-Nature curated
    Subnetwork: S1P4 pathway
NCI-Nature curated
    Subnetwork: S1P5 pathway
NCI-Nature curated
Sumoylation by RanBP2 regulates transcriptional repression NCI-Nature curated
TCR signaling in naïve CD4+ T cells NCI-Nature curated
    Subnetwork: Calcium signaling in the CD4+ TCR pathway
NCI-Nature curated
    Subnetwork: JNK signaling in the CD4+ TCR pathway
NCI-Nature curated
    Subnetwork: Ras signaling in the CD4+ TCR pathway
NCI-Nature curated
TCR signaling in naïve CD8+ T cells NCI-Nature curated
    Subnetwork: Downstream signaling in naïve CD8+ T cells
NCI-Nature curated
TGF-beta receptor signaling NCI-Nature curated
TNF receptor signaling pathway NCI-Nature curated
    Subnetwork: Regulation of p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: Signaling mediated by p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: p38 signaling mediated by MAPKAP kinases
NCI-Nature curated
TRAIL signaling pathway NCI-Nature curated
Thromboxane A2 receptor signaling NCI-Nature curated
VEGFR3 signaling in lymphatic endothelium NCI-Nature curated
Visual signal transduction: Cones NCI-Nature curated
Visual signal transduction: Rods NCI-Nature curated
Wnt signaling NCI-Nature curated
    Subnetwork: Canonical Wnt signaling pathway
NCI-Nature curated
    Subnetwork: Noncanonical Wnt signaling pathway
NCI-Nature curated
a4b1 and a4b7 Integrin signaling NCI-Nature curated
    Subnetwork: Paxillin-dependent events mediated by a4b1
NCI-Nature curated
    Subnetwork: Paxillin-independent events mediated by a4b1 and a4b7
NCI-Nature curated
a6b1 and a6b4 Integrin signaling NCI-Nature curated
amb2 Integrin signaling NCI-Nature curated
mTOR signaling pathway NCI-Nature curated
p38 MAPK signaling pathway NCI-Nature curated
    Subnetwork: Regulation of p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: Signaling mediated by p38-alpha and p38-beta
NCI-Nature curated
    Subnetwork: Signaling mediated by p38-gamma and p38-delta
NCI-Nature curated
    Subnetwork: p38 signaling mediated by MAPKAP kinases
NCI-Nature curated
p75(NTR)-mediated signaling NCI-Nature curated

BioCarta

Pathway Source
ß-arrestins in gpcr desensitization BioCarta Imported
acetylation and deacetylation of rela in nucleus BioCarta Imported
actions of nitric oxide in the heart BioCarta Imported
activation of camp-dependent protein kinase pka BioCarta Imported
activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor BioCarta Imported
activation of pkc through g-protein coupled receptors BioCarta Imported
adp-ribosylation factor BioCarta Imported
agrin in postsynaptic differentiation BioCarta Imported
ahr signal transduction pathway BioCarta Imported
akap95 role in mitosis and chromosome dynamics BioCarta Imported
akt signaling pathway BioCarta Imported
alk in cardiac myocytes BioCarta Imported
alpha-synuclein and parkin-mediated proteolysis in parkinson`s disease BioCarta Imported
alternative complement pathway BioCarta Imported
angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling BioCarta Imported
anthrax toxin mechanism of action BioCarta Imported
antigen processing and presentation BioCarta Imported
antisense pathway BioCarta Imported
apoptotic dna-fragmentation and tissue homeostasis BioCarta Imported
apoptotic signaling in response to dna damage BioCarta Imported
aspirin blocks signaling pathway involved in platelet activation BioCarta Imported
atm signaling pathway BioCarta Imported
attenuation of gpcr signaling BioCarta Imported
b cell survival pathway BioCarta Imported
basic mechanism of action of ppara pparb(d) and pparg and effects on gene expression BioCarta Imported
basic mechanisms of sumoylation BioCarta Imported
bcr signaling pathway BioCarta Imported
bioactive peptide induced signaling pathway BioCarta Imported
bone remodeling BioCarta Imported
brca1 dependent ub ligase activity BioCarta Imported
btg family proteins and cell cycle regulation BioCarta Imported
ca-calmodulin-dependent protein kinase activation BioCarta Imported
cadmium induces dna synthesis and proliferation in macrophages BioCarta Imported
calcium signaling by hbx of hepatitis b virus BioCarta Imported
cardiac protection against ros BioCarta Imported
carm1 and regulation of the estrogen receptor BioCarta Imported
caspase cascade in apoptosis BioCarta Imported
cbl mediated ligand-induced downregulation of egf receptors pathway BioCarta Imported
ccr3 signaling in eosinophils BioCarta Imported
cd40l signaling pathway BioCarta Imported
cdc25 and chk1 regulatory pathway in response to dna damage BioCarta Imported
cdk regulation of dna replication BioCarta Imported
cell cycle: g1/s check point BioCarta Imported
cell cycle: g2/m checkpoint BioCarta Imported
cell to cell adhesion signaling BioCarta Imported
ceramide signaling pathway BioCarta Imported
chaperones modulate interferon signaling pathway BioCarta Imported
chrebp regulation by carbohydrates and camp BioCarta Imported
chromatin remodeling by hswi/snf atp-dependent complexes BioCarta Imported
classical complement pathway BioCarta Imported
control of gene expression by vitamin d receptor BioCarta Imported
control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk) BioCarta Imported
corticosteroids and cardioprotection BioCarta Imported
ctcf: first multivalent nuclear factor BioCarta Imported
cxcr4 signaling pathway BioCarta Imported
cyclin e destruction pathway BioCarta Imported
cycling of ran in nucleocytoplasmic transport BioCarta Imported
cyclins and cell cycle regulation BioCarta Imported
cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway BioCarta Imported
d4gdi signaling pathway BioCarta Imported
degradation of the rar and rxr by the proteasome BioCarta Imported
deregulation of cdk5 in alzheimers disease BioCarta Imported
dicer pathway BioCarta Imported
double stranded rna induced gene expression BioCarta Imported
downregulated of mta-3 in er-negative breast tumors BioCarta Imported
e2f1 destruction pathway BioCarta Imported
effects of calcineurin in keratinocyte differentiation BioCarta Imported
egf signaling pathway BioCarta Imported
eicosanoid metabolism BioCarta Imported
endocytotic role of ndk phosphins and dynamin BioCarta Imported
epo signaling pathway BioCarta Imported
er associated degradation (erad) pathway BioCarta Imported
erk and pi-3 kinase are necessary for collagen binding in corneal epithelia BioCarta Imported
erk1/erk2 mapk signaling pathway BioCarta Imported
erythropoietin mediated neuroprotection through nf-kb BioCarta Imported
estrogen responsive protein efp controls cell cycle and breast tumors growth BioCarta Imported
eukaryotic protein translation BioCarta Imported
extrinsic prothrombin activation pathway BioCarta Imported
fas signaling pathway (cd95) BioCarta Imported
fc epsilon receptor i signaling in mast cells BioCarta Imported
fibrinolysis pathway BioCarta Imported
fmlp induced chemokine gene expression in hmc-1 cells BioCarta Imported
fosb gene expression and drug abuse BioCarta Imported
g-protein signaling through tubby proteins BioCarta Imported
g-secretase mediated erbb4 signaling pathway BioCarta Imported
gamma-aminobutyric acid receptor life cycle pathway BioCarta Imported
gata3 participate in activating the th2 cytokine genes expression BioCarta Imported
generation of amyloid b-peptide by ps1 BioCarta Imported
granzyme a mediated apoptosis pathway BioCarta Imported
growth hormone signaling pathway BioCarta Imported
hemoglobins chaperone BioCarta Imported
hiv-1 defeats host-mediated resistance by cem15 BioCarta Imported
hiv-1 nef: negative effector of fas and tnf BioCarta Imported
hop pathway in cardiac development BioCarta Imported
how does salmonella hijack a cell BioCarta Imported
how progesterone initiates the oocyte maturation BioCarta Imported
human cytomegalovirus and map kinase pathways BioCarta Imported
hypoxia and p53 in the cardiovascular system BioCarta Imported
hypoxia-inducible factor in the cardivascular system BioCarta Imported
ifn alpha signaling pathway BioCarta Imported
ifn gamma signaling pathway BioCarta Imported
igf-1 signaling pathway BioCarta Imported
il 2 signaling pathway BioCarta Imported
il 3 signaling pathway BioCarta Imported
il 4 signaling pathway BioCarta Imported
il 6 signaling pathway BioCarta Imported
il-10 anti-inflammatory signaling pathway BioCarta Imported
il-2 receptor beta chain in t cell activation BioCarta Imported
il-7 signal transduction BioCarta Imported
il12 and stat4 dependent signaling pathway in th1 development BioCarta Imported
il22 soluble receptor signaling pathway BioCarta Imported
inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages BioCarta Imported
induction of apoptosis through dr3 and dr4/5 death receptors BioCarta Imported
influence of ras and rho proteins on g1 to s transition BioCarta Imported
inhibition of cellular proliferation by gleevec BioCarta Imported
inhibition of huntingtons disease neurodegeneration by histone deacetylase inhibitors BioCarta Imported
inhibition of matrix metalloproteinases BioCarta Imported
insulin signaling pathway BioCarta Imported
integrin signaling pathway BioCarta Imported
internal ribosome entry pathway BioCarta Imported
intrinsic prothrombin activation pathway BioCarta Imported
ion channels and their functional role in vascular endothelium BioCarta Imported
ionomycin and phorbal ester signaling pathway BioCarta Imported
keratinocyte differentiation BioCarta Imported
lck and fyn tyrosine kinases in initiation of tcr activation BioCarta Imported
lectin induced complement pathway BioCarta Imported
links between pyk2 and map kinases BioCarta Imported
lissencephaly gene (lis1) in neuronal migration and development BioCarta Imported
map kinase inactivation of smrt corepressor BioCarta Imported
mapkinase signaling pathway BioCarta Imported
mcalpain and friends in cell motility BioCarta Imported
mechanism of acetaminophen activity and toxicity BioCarta Imported
mechanism of gene regulation by peroxisome proliferators via ppara BioCarta Imported
mechanism of protein import into the nucleus BioCarta Imported
mechanisms of transcriptional repression by dna methylation BioCarta Imported
melanocyte development and pigmentation pathway BioCarta Imported
metabolism of anandamide an endogenous cannabinoid BioCarta Imported
mets affect on macrophage differentiation BioCarta Imported
mtor signaling pathway BioCarta Imported
multi-drug resistance factors BioCarta Imported
multi-step regulation of transcription by pitx2 BioCarta Imported
multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation BioCarta Imported
nerve growth factor pathway (ngf) BioCarta Imported
neuroregulin receptor degredation protein-1 controls erbb3 receptor recycling BioCarta Imported
nf-kb signaling pathway BioCarta Imported
nfat and hypertrophy of the heart BioCarta Imported
nfkb activation by nontypeable hemophilus influenzae BioCarta Imported
nitric oxide signaling pathway BioCarta Imported
no2-dependent il-12 pathway in nk cells BioCarta Imported
nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells BioCarta Imported
opposing roles of aif in apoptosis and cell survival BioCarta Imported
overview of telomerase protein component gene htert transcriptional regulation BioCarta Imported
overview of telomerase rna component gene hterc transcriptional regulation BioCarta Imported
oxidative stress induced gene expression via nrf2 BioCarta Imported
p38 mapk signaling pathway BioCarta Imported
p53 signaling pathway BioCarta Imported
pdgf signaling pathway BioCarta Imported
pelp1 modulation of estrogen receptor activity BioCarta Imported
pertussis toxin-insensitive ccr5 signaling in macrophage BioCarta Imported
phosphatidylcholine biosynthesis pathway BioCarta Imported
phosphoinositides and their downstream targets BioCarta Imported
phospholipase c delta in phospholipid associated cell signaling BioCarta Imported
phospholipase c signaling pathway BioCarta Imported
phospholipase c-epsilon pathway BioCarta Imported
phospholipids as signalling intermediaries BioCarta Imported
phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway BioCarta Imported
pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase BioCarta Imported
platelet amyloid precursor protein pathway BioCarta Imported
polyadenylation of mrna BioCarta Imported
prion pathway BioCarta Imported
proteasome complex BioCarta Imported
protein kinase a at the centrosome BioCarta Imported
proteolysis and signaling pathway of notch BioCarta Imported
pten dependent cell cycle arrest and apoptosis BioCarta Imported
rac1 cell motility signaling pathway BioCarta Imported
ras signaling pathway BioCarta Imported
ras-independent pathway in nk cell-mediated cytotoxicity BioCarta Imported
rb tumor suppressor/checkpoint signaling in response to dna damage BioCarta Imported
regulation of bad phosphorylation BioCarta Imported
regulation of cell cycle progression by plk3 BioCarta Imported
regulation of ck1/cdk5 by type 1 glutamate receptors BioCarta Imported
regulation of eif-4e and p70s6 kinase BioCarta Imported
regulation of eif2 BioCarta Imported
regulation of map kinase pathways through dual specificity phosphatases BioCarta Imported
regulation of p27 phosphorylation during cell cycle progression BioCarta Imported
regulation of pgc-1a BioCarta Imported
regulation of spermatogenesis by crem BioCarta Imported
regulation of splicing through sam68 BioCarta Imported
regulation of transcriptional activity by pml BioCarta Imported
regulators of bone mineralization BioCarta Imported
repression of pain sensation by the transcriptional regulator dream BioCarta Imported
reversal of insulin resistance by leptin BioCarta Imported
rho cell motility signaling pathway BioCarta Imported
rho-selective guanine exchange factor akap13 mediates stress fiber formation BioCarta Imported
rna polymerase iii transcription BioCarta Imported
role of ß-arrestins in the activation and targeting of map kinases BioCarta Imported
role of brca1 brca2 and atr in cancer susceptibility BioCarta Imported
role of egf receptor transactivation by gpcrs in cardiac hypertrophy BioCarta Imported
role of erbb2 in signal transduction and oncology BioCarta Imported
role of erk5 in neuronal survival pathway BioCarta Imported
role of mal in rho-mediated activation of srf BioCarta Imported
role of mef2d in t-cell apoptosis BioCarta Imported
role of mitochondria in apoptotic signaling BioCarta Imported
role of nicotinic acetylcholine receptors in the regulation of apoptosis BioCarta Imported
role of parkin in ubiquitin-proteasomal pathway BioCarta Imported
role of pi3k subunit p85 in regulation of actin organization and cell migration BioCarta Imported
role of ppar-gamma coactivators in obesity and thermogenesis BioCarta Imported
role of ran in mitotic spindle regulation BioCarta Imported
roles of ß arrestin dependent recruitment of src kinases in gpcr signaling BioCarta Imported
segmentation clock BioCarta Imported
signal dependent regulation of myogenesis by corepressor mitr BioCarta Imported
signal transduction through il1r BioCarta Imported
signaling pathway from g-protein families BioCarta Imported
skeletal muscle hypertrophy is regulated via akt-mtor pathway BioCarta Imported
sodd/tnfr1 signaling pathway BioCarta Imported
sonic hedgehog receptor ptc1 regulates cell cycle BioCarta Imported
spliceosomal assembly BioCarta Imported
sprouty regulation of tyrosine kinase signals BioCarta Imported
srebp control of lipid synthesis BioCarta Imported
stat3 signaling pathway BioCarta Imported
stathmin and breast cancer resistance to antimicrotubule agents BioCarta Imported
stress induction of hsp regulation BioCarta Imported
sumoylation as a mechanism to modulate ctbp-dependent gene responses BioCarta Imported
sumoylation by ranbp2 regulates transcriptional repression BioCarta Imported
t cell receptor signaling pathway BioCarta Imported
telomeres telomerase cellular aging and immortality BioCarta Imported
tgf beta signaling pathway BioCarta Imported
the 41bb-dependent immune response BioCarta Imported
the co-stimulatory signal during t-cell activation BioCarta Imported
the igf-1 receptor and longevity BioCarta Imported
the information processing pathway at the ifn beta enhancer BioCarta Imported
the prc2 complex sets long-term gene silencing through modification of histone tails BioCarta Imported
thrombin signaling and protease-activated receptors BioCarta Imported
tnf/stress related signaling BioCarta Imported
tnfr1 signaling pathway BioCarta Imported
tnfr2 signaling pathway BioCarta Imported
toll-like receptor pathway BioCarta Imported
tpo signaling pathway BioCarta Imported
transcription factor creb and its extracellular signals BioCarta Imported
transcription regulation by methyltransferase of carm1 BioCarta Imported
transcriptional activation of dbpb from mrna BioCarta Imported
trefoil factors initiate mucosal healing BioCarta Imported
trka receptor signaling pathway BioCarta Imported
tsp-1 induced apoptosis in microvascular endothelial cell BioCarta Imported
tumor suppressor arf inhibits ribosomal biogenesis BioCarta Imported
ucalpain and friends in cell spread BioCarta Imported
vegf hypoxia and angiogenesis BioCarta Imported
visceral fat deposits and the metabolic syndrome BioCarta Imported
visual signal transduction BioCarta Imported
west nile virus BioCarta Imported
wnt lrp6 signalling BioCarta Imported
wnt signaling pathway BioCarta Imported
y branching of actin filaments BioCarta Imported
yaci and bcma stimulation of b cell immune responses BioCarta Imported

BioCarta

Pathway Source
3' -UTR-mediated translational regulation Reactome Imported
3' -UTR-mediated translational regulation Reactome Imported
    Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression
Reactome Imported
APC-Cdc20 mediated degradation of Nek2A Reactome Imported
Apoptosis Reactome Imported
    Subnetwork: Activation and oligomerization of BAK protein
Reactome Imported
    Subnetwork: Activation of BAD and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of BH3-only proteins
Reactome Imported
    Subnetwork: Activation of BIM and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of BMF and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of DNA fragmentation factor
Reactome Imported
    Subnetwork: Activation of NOXA and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of PUMA and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation of Pro-Caspase 8
Reactome Imported
    Subnetwork: Activation of caspases through apoptosome-mediated cleavage
Reactome Imported
    Subnetwork: Activation, myristolyation of BID and translocation to mitochondria
Reactome Imported
    Subnetwork: Activation, translocation and oligomerization of BAX
Reactome Imported
    Subnetwork: Apoptosis induced DNA fragmentation
Reactome Imported
    Subnetwork: Apoptotic cleavage of cell adhesion proteins
Reactome Imported
    Subnetwork: Apoptotic cleavage of cellular proteins
Reactome Imported
    Subnetwork: Apoptotic execution phase
Reactome Imported
    Subnetwork: Apoptotic factor-mediated response
Reactome Imported
    Subnetwork: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Reactome Imported
    Subnetwork: Breakdown of the nuclear lamina
Reactome Imported
    Subnetwork: Caspase-8 is formed from procaspase-8
Reactome Imported
    Subnetwork: Caspase-mediated cleavage of cytoskeletal proteins
Reactome Imported
    Subnetwork: Cytochrome c-mediated apoptotic response
Reactome Imported
    Subnetwork: Death Receptor Signalling
Reactome Imported
    Subnetwork: Extrinsic Pathway for Apoptosis
Reactome Imported
    Subnetwork: FasL/ CD95L signaling
Reactome Imported
    Subnetwork: Formation of apoptosome
Reactome Imported
    Subnetwork: Intrinsic Pathway for Apoptosis
Reactome Imported
    Subnetwork: Regulation of Apoptosis
Reactome Imported
    Subnetwork: Regulation of PAK-2p34 activity by PS-GAP/RHG10
Reactome Imported
    Subnetwork: Regulation of activated PAK-2p34 by proteasome mediated degradation
Reactome Imported
    Subnetwork: Release of apoptotic factors from the mitochondria
Reactome Imported
    Subnetwork: SMAC binds to IAPs
Reactome Imported
    Subnetwork: SMAC-mediated apoptotic response
Reactome Imported
    Subnetwork: SMAC-mediated dissociation of IAP:caspase complexes
Reactome Imported
    Subnetwork: Stimulation of the cell death response by PAK-2p34
Reactome Imported
    Subnetwork: TNF signaling
Reactome Imported
    Subnetwork: TRAIL signaling
Reactome Imported
Biological oxidations Reactome Imported
    Subnetwork: Acetaldehyde is oxidized by NAD+ to form acetate, NADH, and H+
Reactome Imported
    Subnetwork: Acetate, ATP, and coenzyme A react to form acetyl CoA, AMP, and pyrophosphate
Reactome Imported
    Subnetwork: Acetylation
Reactome Imported
    Subnetwork: Alcohol Dehydrogenase
Reactome Imported
    Subnetwork: Aldehyde Dehydrogenase
Reactome Imported
    Subnetwork: Amine Oxidase reactions
Reactome Imported
    Subnetwork: Amino Acid conjugation
Reactome Imported
    Subnetwork: Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Reactome Imported
    Subnetwork: COX reactions
Reactome Imported
    Subnetwork: CYP2E1 reactions
Reactome Imported
    Subnetwork: Conjugation of benzoate with glycine
Reactome Imported
    Subnetwork: Conjugation of carboxylic acids
Reactome Imported
    Subnetwork: Conjugation of phenylacetate with glutamine
Reactome Imported
    Subnetwork: Conjugation of salicylate with glycine
Reactome Imported
    Subnetwork: Cytochrome P450 - arranged by substrate type
Reactome Imported
    Subnetwork: Cytosolic sulfonation of small molecules
Reactome Imported
    Subnetwork: Eicosanoids
Reactome Imported
    Subnetwork: Endogenous sterols
Reactome Imported
    Subnetwork: Ethanol catabolism
Reactome Imported
    Subnetwork: Ethanol is oxidized by NAD+ to form acetaldehyde, NADH, and H+
Reactome Imported
    Subnetwork: FMO oxidizes nucleophiles
Reactome Imported
    Subnetwork: Fatty acids
Reactome Imported
    Subnetwork: Formation of the active cofactor, UDP-glucuronate
Reactome Imported
    Subnetwork: Glucuronidation
Reactome Imported
    Subnetwork: Glutathione conjugation
Reactome Imported
    Subnetwork: Glutathione synthesis
Reactome Imported
    Subnetwork: Methylation
Reactome Imported
    Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2
Reactome Imported
    Subnetwork: Phase 1 - Functionalization of compounds
Reactome Imported
    Subnetwork: Phase II conjugation
Reactome Imported
    Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs
Reactome Imported
    Subnetwork: Sterols are 12-hydroxylated by CYP8B1
Reactome Imported
    Subnetwork: Unknown
Reactome Imported
    Subnetwork: Vitamins
Reactome Imported
    Subnetwork: Xenobiotics
Reactome Imported
Botulinum neurotoxicity Reactome Imported
    Subnetwork: BoNT Light Chain Types A, C1, E cleave SNAP-25
Reactome Imported
    Subnetwork: BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin
Reactome Imported
    Subnetwork: Proteolytic cleavage of SNARE complex proteins
Reactome Imported
    Subnetwork: Translocation of BoNT Light chain
Reactome Imported
Breakdown of hydrogen peroxide to water and molecular oxygen Reactome Imported
Cdc20:Phospho-APC/C mediated degradation of Cyclin A Reactome Imported
Cell Cycle Checkpoints Reactome Imported
    Subnetwork: Activation of ATR in response to replication stress
Reactome Imported
    Subnetwork: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Reactome Imported
    Subnetwork: Amplification of signal from the kinetochores
Reactome Imported
    Subnetwork: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome Imported
    Subnetwork: G1/S DNA Damage Checkpoints
Reactome Imported
    Subnetwork: G2/M Checkpoints
Reactome Imported
    Subnetwork: G2/M DNA damage checkpoint
Reactome Imported
    Subnetwork: G2/M DNA replication checkpoint
Reactome Imported
    Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex
Reactome Imported
    Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Reactome Imported
    Subnetwork: Mitotic Spindle Checkpoint
Reactome Imported
    Subnetwork: Stabilization of p53
Reactome Imported
    Subnetwork: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Reactome Imported
    Subnetwork: p53-Dependent G1 DNA Damage Response
Reactome Imported
    Subnetwork: p53-Dependent G1/S DNA damage checkpoint
Reactome Imported
    Subnetwork: p53-Independent DNA Damage Response
Reactome Imported
    Subnetwork: p53-Independent G1/S DNA damage checkpoint
Reactome Imported
Cell Cycle, Mitotic Reactome Imported
    Subnetwork: APC/C-mediated degradation of cell cycle proteins
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of Cyclin B
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of Securin
Reactome Imported
    Subnetwork: APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome Imported
    Subnetwork: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Reactome Imported
    Subnetwork: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome Imported
    Subnetwork: Activation of the pre-replicative complex
Reactome Imported
    Subnetwork: Assembly of the ORC complex at the origin of replication
Reactome Imported
    Subnetwork: Assembly of the pre-replicative complex
Reactome Imported
    Subnetwork: Autodegradation of Cdh1 by Cdh1:APC/C
Reactome Imported
    Subnetwork: CDC6 association with the ORC:origin complex
Reactome Imported
    Subnetwork: CDK-mediated phosphorylation and removal of Cdc6
Reactome Imported
    Subnetwork: CDT1 association with the CDC6:ORC:origin complex
Reactome Imported
    Subnetwork: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Reactome Imported
    Subnetwork: Cyclin A/B1 associated events during G2/M transition
Reactome Imported
    Subnetwork: Cyclin A:Cdk2-associated events at S phase entry
Reactome Imported
    Subnetwork: Cyclin B2 mediated events
Reactome Imported
    Subnetwork: Cyclin D associated events in G1
Reactome Imported
    Subnetwork: Cyclin E associated events during G1/S transition
Reactome Imported
    Subnetwork: DNA replication initiation
Reactome Imported
    Subnetwork: DNA strand elongation
Reactome Imported
    Subnetwork: E2F mediated regulation of DNA replication
Reactome Imported
    Subnetwork: E2F-enabled inhibition of pre-replication complex formation
Reactome Imported
    Subnetwork: G1 Phase
Reactome Imported
    Subnetwork: G1/S Transition
Reactome Imported
    Subnetwork: G2 Phase
Reactome Imported
    Subnetwork: G2/M Transition
Reactome Imported
    Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization
Reactome Imported
    Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex
Reactome Imported
    Subnetwork: Inhibition of replication initiation of damaged DNA by Rb/E2F1
Reactome Imported
    Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Reactome Imported
    Subnetwork: Lagging Strand Synthesis
Reactome Imported
    Subnetwork: Leading Strand Synthesis
Reactome Imported
    Subnetwork: M Phase
Reactome Imported
    Subnetwork: M/G1 Transition
Reactome Imported
    Subnetwork: Mitotic Metaphase/Anaphase Transition
Reactome Imported
    Subnetwork: Mitotic Prometaphase
Reactome Imported
    Subnetwork: Mitotic Prophase
Reactome Imported
    Subnetwork: Mitotic Telophase /Cytokinesis
Reactome Imported
    Subnetwork: Orc1 removal from chromatin
Reactome Imported
    Subnetwork: Phosphorylation of Emi1
Reactome Imported
    Subnetwork: Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome Imported
    Subnetwork: Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
Reactome Imported
    Subnetwork: Phosphorylation of the APC/C
Reactome Imported
    Subnetwork: Polo-like kinase mediated events
Reactome Imported
    Subnetwork: Polymerase switching
Reactome Imported
    Subnetwork: Processive synthesis on the lagging strand
Reactome Imported
    Subnetwork: Regulation of APC/C activators between G1/S and early anaphase
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate
Reactome Imported
    Subnetwork: S Phase
Reactome Imported
    Subnetwork: SCF(Skp2)-mediated degradation of p27/p21
Reactome Imported
    Subnetwork: SCF-beta-TrCP mediated degradation of Emi1
Reactome Imported
    Subnetwork: Switching of origins to a post-replicative state
Reactome Imported
    Subnetwork: Synthesis of DNA
Reactome Imported
    Subnetwork: Ubiquitin-dependent degradation of Cyclin D
Reactome Imported
    Subnetwork: Ubiquitin-dependent degradation of Cyclin D1
Reactome Imported
    Subnetwork: Unwinding of DNA
Reactome Imported
DNA Repair Reactome Imported
    Subnetwork: ABH2 mediated Reversal of Alkylation Damage
Reactome Imported
    Subnetwork: ABH3 mediated Reversal of Alkylation Damage
Reactome Imported
    Subnetwork: ATM mediated phosphorylation of repair proteins
Reactome Imported
    Subnetwork: ATM mediated response to DNA double-strand break
Reactome Imported
    Subnetwork: Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks
Reactome Imported
    Subnetwork: Assembly of the RAD51-ssDNA nucleoprotein complex
Reactome Imported
    Subnetwork: Base Excision Repair
Reactome Imported
    Subnetwork: Base-Excision Repair, AP Site Formation
Reactome Imported
    Subnetwork: Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
Reactome Imported
    Subnetwork: Cleavage of the damaged purine
Reactome Imported
    Subnetwork: Cleavage of the damaged pyrimidine
Reactome Imported
    Subnetwork: DNA Damage Bypass
Reactome Imported
    Subnetwork: DNA Damage Recognition in GG-NER
Reactome Imported
    Subnetwork: DNA Damage Reversal
Reactome Imported
    Subnetwork: Depurination
Reactome Imported
    Subnetwork: Depyrimidination
Reactome Imported
    Subnetwork: Displacement of DNA glycosylase by APE1
Reactome Imported
    Subnetwork: Double-Strand Break Repair
Reactome Imported
    Subnetwork: Dual incision reaction in GG-NER
Reactome Imported
    Subnetwork: Dual incision reaction in TC-NER
Reactome Imported
    Subnetwork: Formation of incision complex in GG-NER
Reactome Imported
    Subnetwork: Formation of transcription-coupled NER (TC-NER) repair complex
Reactome Imported
    Subnetwork: Gap-filling DNA repair synthesis and ligation in GG-NER
Reactome Imported
    Subnetwork: Gap-filling DNA repair synthesis and ligation in TC-NER
Reactome Imported
    Subnetwork: Global Genomic NER (GG-NER)
Reactome Imported
    Subnetwork: Homologous DNA pairing and strand exchange
Reactome Imported
    Subnetwork: Homologous Recombination Repair
Reactome Imported
    Subnetwork: Homologous recombination repair of replication-independent double-strand breaks
Reactome Imported
    Subnetwork: MRN complex relocalizes to nuclear foci
Reactome Imported
    Subnetwork: Nonhomologous End-joining (NHEJ)
Reactome Imported
    Subnetwork: Nucleotide Excision Repair
Reactome Imported
    Subnetwork: Presynaptic phase of homologous DNA pairing and strand exchange
Reactome Imported
    Subnetwork: Processing of DNA double-strand break ends
Reactome Imported
    Subnetwork: Processing of DNA ends prior to end rejoining
Reactome Imported
    Subnetwork: Recognition and association of DNA glycosylase with site containing an affected purine
Reactome Imported
    Subnetwork: Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Reactome Imported
    Subnetwork: Recruitment of repair and signaling proteins to double-strand breaks
Reactome Imported
    Subnetwork: Removal of DNA patch containing abasic residue
Reactome Imported
    Subnetwork: Repair synthesis for gap-filling by DNA polymerase in TC-NER
Reactome Imported
    Subnetwork: Repair synthesis of patch ~27-30 bases long by DNA polymerase
Reactome Imported
    Subnetwork: Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Reactome Imported
    Subnetwork: Resolution of AP sites via the single-nucleotide replacement pathway
Reactome Imported
    Subnetwork: Resolution of Abasic Sites (AP sites)
Reactome Imported
    Subnetwork: Resolution of D-loop structures
Reactome Imported
    Subnetwork: Resolution of D-loop structures through Holliday junction intermediates
Reactome Imported
    Subnetwork: Resolution of D-loop structures through synthesis-dependent strand-annealing
Reactome Imported
    Subnetwork: Reversal of Alkylation Damage By DNA Dioxygenases
Reactome Imported
    Subnetwork: Transcription-coupled NER (TC-NER)
Reactome Imported
    Subnetwork: Translesion synthesis by DNA polymerases bypassing lesion on DNA template
Reactome Imported
    Subnetwork: Translesion synthesis by HREV1
Reactome Imported
    Subnetwork: Translesion synthesis by Pol eta
Reactome Imported
    Subnetwork: Translesion synthesis by Pol zeta
Reactome Imported
DNA Replication Reactome Imported
    Subnetwork: Activation of the pre-replicative complex
Reactome Imported
    Subnetwork: Assembly of the ORC complex at the origin of replication
Reactome Imported
    Subnetwork: Assembly of the pre-replicative complex
Reactome Imported
    Subnetwork: Association of licensing factors with the pre-replicative complex
Reactome Imported
    Subnetwork: CDC6 association with the ORC:origin complex
Reactome Imported
    Subnetwork: CDK-mediated phosphorylation and removal of Cdc6
Reactome Imported
    Subnetwork: CDT1 association with the CDC6:ORC:origin complex
Reactome Imported
    Subnetwork: DNA Replication Pre-Initiation
Reactome Imported
    Subnetwork: DNA replication initiation
Reactome Imported
    Subnetwork: DNA strand elongation
Reactome Imported
    Subnetwork: Lagging Strand Synthesis
Reactome Imported
    Subnetwork: Leading Strand Synthesis
Reactome Imported
    Subnetwork: Orc1 removal from chromatin
Reactome Imported
    Subnetwork: Polymerase switching
Reactome Imported
    Subnetwork: Processive synthesis on the lagging strand
Reactome Imported
    Subnetwork: Regulation of DNA replication
Reactome Imported
    Subnetwork: Removal of licensing factors from origins
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate
Reactome Imported
    Subnetwork: Switching of origins to a post-replicative state
Reactome Imported
    Subnetwork: Unwinding of DNA
Reactome Imported
Electron Transport Chain Reactome Imported
Elongation arrest and recovery Reactome Imported
Formation of PAPS Reactome Imported
Gap junction trafficking and regulation Reactome Imported
    Subnetwork: Formation of annular gap junctions
Reactome Imported
    Subnetwork: Gap junction assembly
Reactome Imported
    Subnetwork: Gap junction degradation
Reactome Imported
    Subnetwork: Gap junction trafficking
Reactome Imported
    Subnetwork: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Reactome Imported
    Subnetwork: Oligomerization of connexins into connexons
Reactome Imported
    Subnetwork: Regulation of gap junction activity
Reactome Imported
    Subnetwork: Transport of connexins along the secretory pathway
Reactome Imported
    Subnetwork: Transport of connexons to the plasma membrane
Reactome Imported
    Subnetwork: c-src mediated regulation of Cx43 function and closure of gap junctions
Reactome Imported
Gene Expression Reactome Imported
    Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Reactome Imported
    Subnetwork: Cap-dependent Translation Initiation
Reactome Imported
    Subnetwork: Elongation and Processing of Capped Transcripts
Reactome Imported
    Subnetwork: Elongation of Intron-Containing Transcripts and co-transcriptional mRNA splicing
Reactome Imported
    Subnetwork: Eukaryotic Translation Elongation
Reactome Imported
    Subnetwork: Eukaryotic Translation Initiation
Reactome Imported
    Subnetwork: Eukaryotic Translation Termination
Reactome Imported
    Subnetwork: Formation and Maturation of mRNA Transcript
Reactome Imported
    Subnetwork: Formation of RNA Pol II elongation complex
Reactome Imported
    Subnetwork: Formation of a pool of free 40S subunits
Reactome Imported
    Subnetwork: Formation of the Early Elongation Complex
Reactome Imported
    Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex
Reactome Imported
    Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome Imported
    Subnetwork: Generic Transcription Pathway
Reactome Imported
    Subnetwork: Notch-HLH transcription pathway
Reactome Imported
    Subnetwork: Peptide chain elongation
Reactome Imported
    Subnetwork: Post-Elongation Processing of Intron-Containing pre-mRNA
Reactome Imported
    Subnetwork: Post-Elongation Processing of Intronless pre-mRNA
Reactome Imported
    Subnetwork: Post-Elongation Processing of the Transcript
Reactome Imported
    Subnetwork: Processing of Capped Intronless Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Intronless Pre-mRNAs
Reactome Imported
    Subnetwork: RNA Polymerase II Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Elongation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Pre-Initiation
Reactome Imported
    Subnetwork: Recycling of eIF2:GDP
Reactome Imported
    Subnetwork: Ribosomal scanning and start codon recognition
Reactome Imported
    Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP independent Processing of Histone Pre-mRNAs
Reactome Imported
    Subnetwork: Translation
Reactome Imported
    Subnetwork: Translation initiation complex formation
Reactome Imported
    Subnetwork: Transport of Mature Transcript to Cytoplasm
Reactome Imported
    Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts
Reactome Imported
    Subnetwork: Transport of the SLBP Dependant Mature mRNA
Reactome Imported
    Subnetwork: Transport of the SLBP independent Mature mRNA
Reactome Imported
    Subnetwork: mRNA 3'-end processing
Reactome Imported
    Subnetwork: mRNA Capping
Reactome Imported
    Subnetwork: mRNA Splicing
Reactome Imported
    Subnetwork: mRNA Splicing - Major Pathway
Reactome Imported
    Subnetwork: mRNA Splicing - Minor Pathway
Reactome Imported
HIV Infection Reactome Imported
    Subnetwork: 2-LTR circle formation
Reactome Imported
    Subnetwork: APOBEC3G mediated resistance to HIV-1 infection
Reactome Imported
    Subnetwork: Abortive elongation of HIV-1 transcript in the absence of Tat
Reactome Imported
    Subnetwork: Autointegration results in viral DNA circles
Reactome Imported
    Subnetwork: Binding and entry of HIV virion
Reactome Imported
    Subnetwork: Early Phase of HIV Life Cycle
Reactome Imported
    Subnetwork: Formation of HIV-1 elongation complex containing HIV-1 Tat
Reactome Imported
    Subnetwork: Formation of the HIV-1 Early Elongation Complex
Reactome Imported
    Subnetwork: HIV Life Cycle
Reactome Imported
    Subnetwork: HIV-1 Transcription Elongation
Reactome Imported
    Subnetwork: HIV-1 Transcription Initiation
Reactome Imported
    Subnetwork: HIV-1 Transcription Pre-Initiation
Reactome Imported
    Subnetwork: Host Interactions of HIV factors
Reactome Imported
    Subnetwork: Integration of provirus
Reactome Imported
    Subnetwork: Integration of viral DNA into host genomic DNA
Reactome Imported
    Subnetwork: Interactions of Rev with host cellular proteins
Reactome Imported
    Subnetwork: Interactions of Tat with host cellular proteins
Reactome Imported
    Subnetwork: Interactions of Vpr with host cellular proteins
Reactome Imported
    Subnetwork: Late Phase of HIV Life Cycle
Reactome Imported
    Subnetwork: Minus-strand DNA synthesis
Reactome Imported
    Subnetwork: Nef Mediated CD4 Down-regulation
Reactome Imported
    Subnetwork: Nef Mediated CD8 Down-regulation
Reactome Imported
    Subnetwork: Nef and signal transduction
Reactome Imported
    Subnetwork: Nef mediated downregulation of CD28 cell surface expression
Reactome Imported
    Subnetwork: Nef mediated downregulation of MHC class I complex cell surface expression
Reactome Imported
    Subnetwork: Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
Reactome Imported
    Subnetwork: Nuclear import of Rev protein
Reactome Imported
    Subnetwork: Plus-strand DNA synthesis
Reactome Imported
    Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE
Reactome Imported
    Subnetwork: RNA Polymerase II HIV-1 Promoter Escape
Reactome Imported
    Subnetwork: Rev-mediated nuclear export of HIV-1 RNA
Reactome Imported
    Subnetwork: Reverse Transcription of HIV RNA
Reactome Imported
    Subnetwork: Tat-mediated elongation of the HIV-1 transcript
Reactome Imported
    Subnetwork: The role of Nef in HIV-1 replication and disease pathogenesis
Reactome Imported
    Subnetwork: Transcription of the HIV genome
Reactome Imported
    Subnetwork: Uncoating of the HIV Virion
Reactome Imported
    Subnetwork: Vif-mediated degradation of APOBEC3G
Reactome Imported
    Subnetwork: Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
Reactome Imported
    Subnetwork: Vpr-mediated nuclear import of PICs
Reactome Imported
    Subnetwork: Vpu mediated degradation of CD4
Reactome Imported
HIV-1 elongation arrest and recovery Reactome Imported
Hemostasis Reactome Imported
    Subnetwork: Basigin interactions
Reactome Imported
    Subnetwork: Cell surface interactions at the vascular wall
Reactome Imported
    Subnetwork: Collagen adhesion via Gp IV
Reactome Imported
    Subnetwork: Collagen adhesion via alpha 2 beta 1 glycoprotein
Reactome Imported
    Subnetwork: Collagen-mediated activation cascade
Reactome Imported
    Subnetwork: Common Pathway
Reactome Imported
    Subnetwork: Disinhibition of SNARE formation
Reactome Imported
    Subnetwork: Dissolution of Fibrin Clot
Reactome Imported
    Subnetwork: Effects of IP3
Reactome Imported
    Subnetwork: Effects on Ca++ levels
Reactome Imported
    Subnetwork: Elevation of cytosolic Ca++ levels
Reactome Imported
    Subnetwork: Exocytosis of Alpha granule
Reactome Imported
    Subnetwork: Exocytosis of Dense granule
Reactome Imported
    Subnetwork: Extrinsic Pathway
Reactome Imported
    Subnetwork: Formation of Fibrin Clot (Clotting Cascade)
Reactome Imported
    Subnetwork: Formation of Platelet plug
Reactome Imported
    Subnetwork: Further platelet releasate
Reactome Imported
    Subnetwork: G alpha 12 cascade
Reactome Imported
    Subnetwork: G alpha Q cascade
Reactome Imported
    Subnetwork: G-protein cascades
Reactome Imported
    Subnetwork: Intrinsic Pathway
Reactome Imported
    Subnetwork: PECAM1 interactions
Reactome Imported
    Subnetwork: PLC-mediated hydrolysis
Reactome Imported
    Subnetwork: Phospholipase-mediated signalling
Reactome Imported
    Subnetwork: Platelet Activation
Reactome Imported
    Subnetwork: Platelet Adhesion to exposed collagen
Reactome Imported
    Subnetwork: Platelet activation triggers
Reactome Imported
    Subnetwork: Platelet degranulation
Reactome Imported
    Subnetwork: Plug Formation
Reactome Imported
    Subnetwork: Response to elevated platelet cytosolic Ca++
Reactome Imported
    Subnetwork: Thrombin-activated activation cascade
Reactome Imported
    Subnetwork: Thrombin-mediated activation of PARs
Reactome Imported
    Subnetwork: Tie2 Signaling
Reactome Imported
    Subnetwork: vWF interaction with collagen
Reactome Imported
Influenza Infection Reactome Imported
    Subnetwork: Assembly of Viral Components at the Budding Site
Reactome Imported
    Subnetwork: Budding
Reactome Imported
    Subnetwork: Entry of Influenza Virion into Host Cell via Endocytosis
Reactome Imported
    Subnetwork: Export of Viral Ribonucleoproteins from Nucleus
Reactome Imported
    Subnetwork: Fusion and Uncoating of the Influenza Virion
Reactome Imported
    Subnetwork: Fusion of the Influenza Virion to the Host Cell Endosome
Reactome Imported
    Subnetwork: Host Interactions with Influenza Factors
Reactome Imported
    Subnetwork: Influenza Life Cycle
Reactome Imported
    Subnetwork: Influenza Viral RNA Transcription and Replication
Reactome Imported
    Subnetwork: Influenza Virus Induced Apoptosis
Reactome Imported
    Subnetwork: Inhibition of Host mRNA Processing and RNA Silencing
Reactome Imported
    Subnetwork: Inhibition of IFN-beta
Reactome Imported
    Subnetwork: Inhibition of Interferon Synthesis
Reactome Imported
    Subnetwork: Inhibition of PKR
Reactome Imported
    Subnetwork: NEP/NS2 Interacts with the Cellular Export Machinery
Reactome Imported
    Subnetwork: NS1 Mediated Effects on Host Pathways
Reactome Imported
    Subnetwork: Packaging of Eight RNA Segments
Reactome Imported
    Subnetwork: Release
Reactome Imported
    Subnetwork: Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus
Reactome Imported
    Subnetwork: Transport of Ribonucleoproteins into the Host Nucleus
Reactome Imported
    Subnetwork: Uncoating of the Influenza Virion
Reactome Imported
    Subnetwork: Viral Messenger RNA Synthesis
Reactome Imported
    Subnetwork: Viral RNP Complexes in the Host Cell Nucleus
Reactome Imported
    Subnetwork: Viral mRNA Translation
Reactome Imported
    Subnetwork: Virus Assembly and Release
Reactome Imported
    Subnetwork: cRNA Synthesis
Reactome Imported
    Subnetwork: vRNA Synthesis
Reactome Imported
    Subnetwork: vRNP Assembly
Reactome Imported
Inhibition of HSL Reactome Imported
Integration of energy metabolism Reactome Imported
    Subnetwork: AMPK inhibits chREBP transcriptional activation activity
Reactome Imported
    Subnetwork: Activated AMPK stimulates fatty-acid oxidation in muscle
Reactome Imported
    Subnetwork: ChREBP activates metabolic gene expression
Reactome Imported
    Subnetwork: G(s)-alpha mediated events in glucagon signalling
Reactome Imported
    Subnetwork: Glucagon signaling in metabolic regulation
Reactome Imported
    Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix
Reactome Imported
    Subnetwork: Insulin effects increased synthesis of Xylulose-5-Phosphate
Reactome Imported
    Subnetwork: PKA activation in glucagon signalling
Reactome Imported
    Subnetwork: PKA-mediated phosphorylation of key metabolic factors
Reactome Imported
    Subnetwork: PP2A-mediated dephosphorylation of key metabolic factors
Reactome Imported
    Subnetwork: Regulation of pyruvate dehydrogenase complex (PDC)
Reactome Imported
Integrin cell surface interactions Reactome Imported
Lipid and lipoprotein metabolism Reactome Imported
    Subnetwork: Androgen biosynthesis
Reactome Imported
    Subnetwork: Beta oxidation of butanoyl-CoA to acetyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Reactome Imported
    Subnetwork: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Reactome Imported
    Subnetwork: Beta oxidation of myristoyl-CoA to lauroyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Reactome Imported
    Subnetwork: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Reactome Imported
    Subnetwork: Cholesterol biosynthesis
Reactome Imported
    Subnetwork: Chylomicron-mediated lipid transport
Reactome Imported
    Subnetwork: Conversion of Fatty Acyl-CoA to Phosphatidic Acid
Reactome Imported
    Subnetwork: Conversion of Phosphatidic Acid to Diacylglycerol
Reactome Imported
    Subnetwork: Digestion of dietary lipid
Reactome Imported
    Subnetwork: Estrogen biosynthesis
Reactome Imported
    Subnetwork: Fatty Acyl-CoA Biosynthesis
Reactome Imported
    Subnetwork: Formation of Acetoacetic Acid
Reactome Imported
    Subnetwork: Formation of Cytosolic Glycerol-3-phosphate
Reactome Imported
    Subnetwork: Glucocorticoid biosynthesis
Reactome Imported
    Subnetwork: HDL-mediated lipid transport
Reactome Imported
    Subnetwork: Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Reactome Imported
    Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix
Reactome Imported
    Subnetwork: Ketone body metabolism
Reactome Imported
    Subnetwork: LDL endocytosis
Reactome Imported
    Subnetwork: Lipoprotein metabolism
Reactome Imported
    Subnetwork: Metabolism of bile acids and bile salts
Reactome Imported
    Subnetwork: Mineralocorticoid biosynthesis
Reactome Imported
    Subnetwork: Mitochondrial Fatty Acid Beta-Oxidation
Reactome Imported
    Subnetwork: Pregnenolone biosynthesis
Reactome Imported
    Subnetwork: Recycling of bile acids and salts
Reactome Imported
    Subnetwork: Steroid hormone biosynthesis
Reactome Imported
    Subnetwork: Steroid metabolism
Reactome Imported
    Subnetwork: Synthesis of Ketone Bodies
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome Imported
    Subnetwork: Synthesis of lysophosphatidic acid from glycerol-3-phosphate
Reactome Imported
    Subnetwork: Synthesis of phosphatidic acid from lysophosphatidic acid
Reactome Imported
    Subnetwork: Trafficking of dietary sterols
Reactome Imported
    Subnetwork: Transformation of lanosterol to cholesterol
Reactome Imported
    Subnetwork: Triacylglyceride Biosynthesis
Reactome Imported
    Subnetwork: Utilization of Ketone Bodies
Reactome Imported
    Subnetwork: mitochondrial fatty acid beta-oxidation of saturated fatty acids
Reactome Imported
    Subnetwork: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome Imported
Mal Cascade Reactome Imported
Membrane Trafficking Reactome Imported
    Subnetwork: COPI Mediated Transport
Reactome Imported
    Subnetwork: COPII (Coat Protein 2) Mediated Vesicle Transport
Reactome Imported
    Subnetwork: ER to Golgi Transport
Reactome Imported
    Subnetwork: Golgi to ER Retrograde Transport
Reactome Imported
    Subnetwork: Vamp2 associated Clathrin derived vesicle budding
Reactome Imported
    Subnetwork: Vamp7 associated clathrin derived vesicle budding
Reactome Imported
    Subnetwork: Vamp8 associated clathrin derived vesicle budding
Reactome Imported
    Subnetwork: trans-Golgi Network Vesicle Budding
Reactome Imported
Metabolism of amino acids Reactome Imported
    Subnetwork: Agmatine biosynthesis
Reactome Imported
    Subnetwork: Alanine metabolism
Reactome Imported
    Subnetwork: Amino acid uptake across the plasma membrane
Reactome Imported
    Subnetwork: Aspartate, asparagine, glutamate, and glutamine metabolism
Reactome Imported
    Subnetwork: Branched-chain amino acid catabolism
Reactome Imported
    Subnetwork: Carnitine synthesis
Reactome Imported
    Subnetwork: Creatine metabolism
Reactome Imported
    Subnetwork: Histidine catabolism
Reactome Imported
    Subnetwork: Interconversion of polyamines
Reactome Imported
    Subnetwork: Isoleucine catabolism
Reactome Imported
    Subnetwork: Leucine catabolism
Reactome Imported
    Subnetwork: Lysine catabolism
Reactome Imported
    Subnetwork: Metabolism of polyamines
Reactome Imported
    Subnetwork: Ornithine and proline metabolism
Reactome Imported
    Subnetwork: Ornithine metabolism
Reactome Imported
    Subnetwork: Oxidative decarboxylation of alpha-keto-beta-methylvalerate to alpha-methylbutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase
Reactome Imported
    Subnetwork: Oxidative decarboxylation of alpha-ketoadipate to glutaryl CoA by alpha-ketoglutarate dehydrogenase
Reactome Imported
    Subnetwork: Oxidative decarboxylation of alpha-ketoisocaproate to isovaleryl-CoA by branched-chain alpha-ketoacid dehydrogenase
Reactome Imported
    Subnetwork: Oxidative decarboxylation of alpha-ketoisovalerate to isobutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase
Reactome Imported
    Subnetwork: Phenylalanine and tyrosine catabolism
Reactome Imported
    Subnetwork: Proline catabolism
Reactome Imported
    Subnetwork: Proline synthesis
Reactome Imported
    Subnetwork: Regulation of ornithine decarboxylase (ODC)
Reactome Imported
    Subnetwork: Tryptophan catabolism
Reactome Imported
    Subnetwork: Urea synthesis
Reactome Imported
    Subnetwork: Valine catabolism
Reactome Imported
Metabolism of carbohydrates Reactome Imported
    Subnetwork: (1,6)-alpha-glucose residues are removed, as D-glucose, from limit dextrin by debranching enzyme
Reactome Imported
    Subnetwork: 1,3-bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
Reactome Imported
    Subnetwork: 5-Phosphoribose 1-diphosphate biosynthesis
Reactome Imported
    Subnetwork: Debranching enzyme transfers 3-glucose blocks from branches in limit dextrin
Reactome Imported
    Subnetwork: Digestion of dietary carbohydrate
Reactome Imported
    Subnetwork: Dihydroxyacetone phosphate is isomerized to form glyceraldehyde-3-phosphate
Reactome Imported
    Subnetwork: Fructose 6-phosphate and ATP react to form fructose 2,6-bisphosphate and ADP
Reactome Imported
    Subnetwork: Fructose catabolism
Reactome Imported
    Subnetwork: Galactose catabolism
Reactome Imported
    Subnetwork: Gluconeogenesis
Reactome Imported
    Subnetwork: Glucose + ATP => glucose-6-phosphate + ADP
Reactome Imported
    Subnetwork: Glucose 6-phosphate is isomerized to form fructose-6-phosphate
Reactome Imported
    Subnetwork: Glucose is carried across the plasma membrane by a glucose transport protein (GLUT)
Reactome Imported
    Subnetwork: Glucose metabolism
Reactome Imported
    Subnetwork: Glucose uptake
Reactome Imported
    Subnetwork: Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+
Reactome Imported
    Subnetwork: Glycogen branching enzyme transfers terminal alpha(1,4)glucose blocks to form alpha(1,6) branches
Reactome Imported
    Subnetwork: Glycogen breakdown (glycogenolysis)
Reactome Imported
    Subnetwork: Glycogen synthase catalyzes the addition of glucose residues to the non-reducing end of a (1,4)-alpha-D-glucose multimer
Reactome Imported
    Subnetwork: Glycogen synthesis
Reactome Imported
    Subnetwork: Glycogen-glycogenin reacts with n orthophosphates, yielding n glucose 1-phosphates and limit dextrin-glycogenin
Reactome Imported
    Subnetwork: Glycogenin catalyzes the synthesis of an oligo(1,4)glucose moiety covalently attached to itself
Reactome Imported
    Subnetwork: Glycolysis
Reactome Imported
    Subnetwork: Hexose uptake
Reactome Imported
    Subnetwork: Negative Regulation of Glucokinase by Glucokinase Regulatory Protein
Reactome Imported
    Subnetwork: Pentose phosphate pathway (hexose monophosphate shunt)
Reactome Imported
    Subnetwork: Phosphoenolpyruvate and ADP react to form pyruvate and ATP
Reactome Imported
    Subnetwork: Phosphorylase kinase activates glycogen phosphorylase
Reactome Imported
    Subnetwork: Phosphorylated glycogen synthase catalyzes the addition of glucose residues to the non-reducing end of a (1,4)-alpha-D-glucose multimer when activated by glucose-6-phosphate
Reactome Imported
    Subnetwork: Poly{(1,4)-alpha-glucosyl} glycogenin reacts with n orthophosphates to form glycogenin and n D-glucose 1-phosphates
Reactome Imported
    Subnetwork: Pyruvate metabolism
Reactome Imported
    Subnetwork: UTP and glucose 1-phosphate react to form UDP-glucose and pyrophosphate
Reactome Imported
Metabolism of nitric oxide Reactome Imported
    Subnetwork: NOSIP mediated eNOS trafficking
Reactome Imported
    Subnetwork: NOSTRIN mediated eNOS trafficking
Reactome Imported
    Subnetwork: eNOS activation
Reactome Imported
    Subnetwork: eNOS activation and regulation
Reactome Imported
    Subnetwork: eNOS acylation cycle
Reactome Imported
Metabolism of non-coding RNA Reactome Imported
    Subnetwork: snRNP Assembly
Reactome Imported
Metabolism of vitamins and cofactors Reactome Imported
    Subnetwork: Biotin metabolism
Reactome Imported
    Subnetwork: Coenzyme A biosynthesis
Reactome Imported
    Subnetwork: Metabolism of folate and pterines
Reactome Imported
    Subnetwork: Metabolism of water-soluble vitamins and cofactors
Reactome Imported
    Subnetwork: Nicotinamide salvaging
Reactome Imported
    Subnetwork: Nicotinate metabolism
Reactome Imported
    Subnetwork: Vitamin B1 (thiamin) metabolism
Reactome Imported
    Subnetwork: Vitamin B2 (riboflavin) metabolism
Reactome Imported
    Subnetwork: Vitamin B5 (pantothenate) metabolism
Reactome Imported
    Subnetwork: Vitamin C (ascorbate) metabolism
Reactome Imported
Mitochondrial Uncoupling Proteins Reactome Imported
    Subnetwork: The fatty acid cycling model
Reactome Imported
    Subnetwork: The proton buffering model
Reactome Imported
Nucleotide metabolism Reactome Imported
    Subnetwork: ATP formation
Reactome Imported
    Subnetwork: Conversion of cytosolic inosine 5'-monophosphate (IMP), NAD+, and H2O to xanthosine 5'-monophosphate (XMP) and NADH + H+
Reactome Imported
    Subnetwork: Conversion of cytosolic inosine 5'-monophosphate, L-aspartate, and GTP to adenylosuccinate, guanosine 5'-diphosphate, and orthophosphate
Reactome Imported
    Subnetwork: De novo synthesis of IMP
Reactome Imported
    Subnetwork: De novo synthesis of the pyrimidine ring and conversion to UMP
Reactome Imported
    Subnetwork: Deoxyribonucleotide salvage
Reactome Imported
    Subnetwork: Formation of ATP by chemiosmotic coupling
Reactome Imported
    Subnetwork: Guanine formation
Reactome Imported
    Subnetwork: Hydrolysis of cytosolic nucleoside 5'- and 3'-monophosphates by 5',3'-nucleotidase, cytosolic
Reactome Imported
    Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic IA
Reactome Imported
    Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic IB
Reactome Imported
    Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic II
Reactome Imported
    Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase, cytosolic III
Reactome Imported
    Subnetwork: Hydrolysis of extracellular nucleoside 5'-monophosphates by plasma membrane-bound 5'-nucleotidase
Reactome Imported
    Subnetwork: Hydrolysis of mitochondrial nucleoside 5'- and 3'-monophosphates by 5',3'-nucleotidase, mitochondrial
Reactome Imported
    Subnetwork: Hydrolysis of nucleoside 5'-monophosphates to nucleosides plus orthophosphate
Reactome Imported
    Subnetwork: Hypoxanthine formation
Reactome Imported
    Subnetwork: Inosine formation
Reactome Imported
    Subnetwork: Phosphorylation of cytosolic nucleosides by adenosine kinase
Reactome Imported
    Subnetwork: Phosphorylation of cytosolic nucleosides by deoxycytidine kinase
Reactome Imported
    Subnetwork: Phosphorylation of cytosolic nucleosides by thymidine kinase 1, soluble
Reactome Imported
    Subnetwork: Phosphorylation of cytosolic nucleosides by uridine-cytidine kinase 1
Reactome Imported
    Subnetwork: Phosphorylation of cytosolic nucleosides by uridine-cytidine kinase 2
Reactome Imported
    Subnetwork: Phosphorylation of mitochondrial nucleosides by deoxyguanosine kinase
Reactome Imported
    Subnetwork: Phosphorylation of mitochondrial nucleosides by thymidine kinase 2, mitochondrial
Reactome Imported
    Subnetwork: Phosphorylation of nucleosides to form nucleoside 5'-monophosphates
Reactome Imported
    Subnetwork: Purine biosynthesis
Reactome Imported
    Subnetwork: Purine catabolism
Reactome Imported
    Subnetwork: Purine metabolism
Reactome Imported
    Subnetwork: Purine salvage reactions
Reactome Imported
    Subnetwork: Pyrimidine biosynthesis (interconversion)
Reactome Imported
    Subnetwork: Pyrimidine catabolism
Reactome Imported
    Subnetwork: Pyrimidine metabolism
Reactome Imported
    Subnetwork: Pyrimidine salvage reactions
Reactome Imported
    Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (glutaredoxin)
Reactome Imported
    Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin)
Reactome Imported
    Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and glutaredoxin
Reactome Imported
    Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin
Reactome Imported
    Subnetwork: Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin)
Reactome Imported
    Subnetwork: Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin
Reactome Imported
    Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides
Reactome Imported
    Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides by thymidine phosphorylase
Reactome Imported
    Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides by uridine phosphorylase 1
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A hexamer
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A,B heterohexamer
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase B hexamer
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase C hexamer
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by UMP-CMP kinase
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by adenylate kinase 1
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by adenylate kinase 5
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by deoxythymidylate kinase (thymidylate kinase)
Reactome Imported
    Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by guanylate kinase 1
Reactome Imported
    Subnetwork: Reversible phosphorylation of mitochondrial nucleoside diphosphates by nucleoside diphosphate kinase D, mitochondrial hexamer
Reactome Imported
    Subnetwork: Reversible phosphorylation of mitochondrial nucleoside monophosphates by adenylate kinase 2
Reactome Imported
    Subnetwork: Reversible phosphorylation of nucleoside diphosphates
Reactome Imported
    Subnetwork: Reversible phosphorylation of nucleoside monophosphates
Reactome Imported
    Subnetwork: Ribonucleotide salvage
Reactome Imported
    Subnetwork: Synthesis of deoxyribonucleoside 5'-diphosphates from ribonucleoside 5'-diphosphates
Reactome Imported
    Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Reactome Imported
    Subnetwork: Xanthine formation
Reactome Imported
    Subnetwork: dATP formation
Reactome Imported
    Subnetwork: dGTP formation
Reactome Imported
Pausing and recovery of HIV-1 elongation Reactome Imported
Pausing and recovery of Tat-mediated HIV-1 elongation Reactome Imported
Pausing and recovery of elongation Reactome Imported
Phase 1 functionalization Reactome Imported
    Subnetwork: Amine Oxidase reactions
Reactome Imported
    Subnetwork: COX reactions
Reactome Imported
    Subnetwork: Cytochrome p450
Reactome Imported
    Subnetwork: Ester hydrolysis
Reactome Imported
    Subnetwork: FMO reactions
Reactome Imported
    Subnetwork: Hydrolases
Reactome Imported
    Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2
Reactome Imported
    Subnetwork: N-oxidation of nitrogen compounds
Reactome Imported
    Subnetwork: P450 Dehalogenation
Reactome Imported
    Subnetwork: P450 Dehydrogenation of alkanes to form alkenes
Reactome Imported
    Subnetwork: P450 Epoxidations
Reactome Imported
    Subnetwork: P450 Hydroxylations
Reactome Imported
    Subnetwork: P450 Prostaglandin isomerizations
Reactome Imported
    Subnetwork: P450 oxidation
Reactome Imported
    Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs
Reactome Imported
    Subnetwork: Simple hydroxylation
Reactome Imported
Porphyrin metabolism Reactome Imported
    Subnetwork: Heme biosynthesis
Reactome Imported
Post-translational protein modification Reactome Imported
    Subnetwork: Attachment of GPI anchor to uPAR
Reactome Imported
    Subnetwork: Gamma-carboxylation of protein precursors
Reactome Imported
    Subnetwork: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Reactome Imported
    Subnetwork: Hypusine synthesis from eIF5A-lysine
Reactome Imported
    Subnetwork: Removal of aminoterminal propeptides from gamma-carboxylated proteins
Reactome Imported
    Subnetwork: Synthesis of GPI-anchored proteins
Reactome Imported
    Subnetwork: Synthesis of dolichol-phosphate mannose
Reactome Imported
    Subnetwork: Synthesis of glycosylphosphatidylinositol (GPI)
Reactome Imported
    Subnetwork: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Reactome Imported
Propionyl-CoA catabolism Reactome Imported
Pyruvate metabolism and TCA cycle Reactome Imported
    Subnetwork: Citric acid cycle (TCA cycle)
Reactome Imported
    Subnetwork: Pyruvate metabolism
Reactome Imported
Regulation of activated PAK-2p34 by proteasome mediated degradation Reactome Imported
Regulation of beta-cell development Reactome Imported
    Subnetwork: AKT-mediated inactivation of FOXO1A
Reactome Imported
    Subnetwork: Regulation of gene expression in beta cells
Reactome Imported
Regulatory RNA pathways Reactome Imported
    Subnetwork: MicroRNA biogenesis
Reactome Imported
Signal attenuation Reactome Imported
Signaling by TGF beta Reactome Imported
Signaling by BMP Reactome Imported
Signaling by EGFR Reactome Imported
    Subnetwork: EGFR downregulation
Reactome Imported
    Subnetwork: EGFR interacts with phospholipase C-gamma
Reactome Imported
    Subnetwork: Gab1 signalosome
Reactome Imported
    Subnetwork: Grb2 events in EGFR signaling
Reactome Imported
    Subnetwork: Shc events in EGFR signaling
Reactome Imported
Signaling by FGFR Reactome Imported
    Subnetwork: FGFR ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1c and Klotho ligand binding and activation
Reactome Imported
    Subnetwork: FGFR1c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR2c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3 ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3b ligand binding and activation
Reactome Imported
    Subnetwork: FGFR3c ligand binding and activation
Reactome Imported
    Subnetwork: FGFR4 ligand binding and activation
Reactome Imported
Signaling by GPCR Reactome Imported
    Subnetwork: Class A/1 (Rhodopsin-like receptors)
Reactome Imported
    Subnetwork: Peptide ligand-binding receptors
Reactome Imported
Signaling by Insulin receptor Reactome Imported
    Subnetwork: Activation of PKB
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: IRS activation
Reactome Imported
    Subnetwork: IRS-mediated signalling
Reactome Imported
    Subnetwork: IRS-related events
Reactome Imported
    Subnetwork: Inhibition of TSC complex formation by PKB
Reactome Imported
    Subnetwork: Insulin receptor recycling
Reactome Imported
    Subnetwork: Insulin receptor signalling cascade
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: PDE3B signalling
Reactome Imported
    Subnetwork: PI3K Cascade
Reactome Imported
    Subnetwork: PKB-mediated events
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Release of eIF4E
Reactome Imported
    Subnetwork: S6K1 signalling
Reactome Imported
    Subnetwork: S6K1-mediated signalling
Reactome Imported
    Subnetwork: SHC activation
Reactome Imported
    Subnetwork: SHC-mediated signalling
Reactome Imported
    Subnetwork: SHC-related events
Reactome Imported
    Subnetwork: SOS-mediated signalling
Reactome Imported
    Subnetwork: mTOR signalling
Reactome Imported
    Subnetwork: mTORC1-mediated signalling
Reactome Imported
Signaling by Notch Reactome Imported
    Subnetwork: A third proteolytic cleavage releases NICD
Reactome Imported
    Subnetwork: Maturation of Notch precursor via proteolytic cleavage
Reactome Imported
    Subnetwork: Mature Notch receptor trafficks to plasma membrane
Reactome Imported
    Subnetwork: NICD trafficks to nucleus
Reactome Imported
    Subnetwork: Notch receptor binds with a ligand
Reactome Imported
    Subnetwork: Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
Reactome Imported
    Subnetwork: Transport of Notch receptor precursor to golgi
Reactome Imported
Signaling by Rho GTPases Reactome Imported
    Subnetwork: Rho GTPase cycle
Reactome Imported
Signaling by VEGF Reactome Imported
    Subnetwork: Neurophilin interactions with VEGF and VEGFR
Reactome Imported
    Subnetwork: VEGF binds to VEGFR leading to receptor dimerization
Reactome Imported
    Subnetwork: VEGF ligand-receptor interactions
Reactome Imported
Signaling by Wnt Reactome Imported
    Subnetwork: Beta-catenin phosphorylation cascade
Reactome Imported
    Subnetwork: Degradation of beta-catenin by the destruction complex
Reactome Imported
Signaling in Immune system Reactome Imported
    Subnetwork: Activated TLR4 signalling
Reactome Imported
    Subnetwork: Activation of C3 and C5
Reactome Imported
    Subnetwork: Alternative complement activation
Reactome Imported
    Subnetwork: Basigin interactions
Reactome Imported
    Subnetwork: Cell surface interactions at the vascular wall
Reactome Imported
    Subnetwork: Classical antibody-mediated complement activation
Reactome Imported
    Subnetwork: Complement cascade
Reactome Imported
    Subnetwork: Creation of C4 and C2 activators
Reactome Imported
    Subnetwork: Downstream TCR signaling
Reactome Imported
    Subnetwork: Generation of second messenger molecules
Reactome Imported
    Subnetwork: Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Reactome Imported
    Subnetwork: Initial triggering of complement
Reactome Imported
    Subnetwork: Innate Immunity Signaling
Reactome Imported
    Subnetwork: LPS transferred from LBP carrier to CD14
Reactome Imported
    Subnetwork: Lectin pathway of complement activation
Reactome Imported
    Subnetwork: MyD88 cascade
Reactome Imported
    Subnetwork: PECAM1 interactions
Reactome Imported
    Subnetwork: Phosphorylation of CD3 and TCR zeta chains
Reactome Imported
    Subnetwork: TCR signaling
Reactome Imported
    Subnetwork: TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade
Reactome Imported
    Subnetwork: TRAM Cascade
Reactome Imported
    Subnetwork: Terminal pathway of complement
Reactome Imported
    Subnetwork: Tie2 Signaling
Reactome Imported
    Subnetwork: Toll Like Receptor 10 (TLR10) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 2 Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 3 (TLR3) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 4 (TLR4) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 5 (TLR5) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 7/8 (TLR7/8) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor 9 (TLR9) Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor TLR1:TLR2 Cascade
Reactome Imported
    Subnetwork: Toll Like Receptor TLR6:TLR2 Cascade
Reactome Imported
    Subnetwork: Toll Receptor Cascades
Reactome Imported
    Subnetwork: Translocation of ZAP-70 to Immunological synapse
Reactome Imported
    Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates RIP1
Reactome Imported
    Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates TBK1
Reactome Imported
Signalling by NGF Reactome Imported
    Subnetwork: AKT phosphorylates targets in the cytosol
Reactome Imported
    Subnetwork: AKT phosphorylates targets in the nucleus
Reactome Imported
    Subnetwork: ARMS-mediated activation
Reactome Imported
    Subnetwork: Activation of TRKA receptors
Reactome Imported
    Subnetwork: Axonal growth inhibition (RHOA activation)
Reactome Imported
    Subnetwork: Axonal growth stimulation
Reactome Imported
    Subnetwork: CREB phosphorylation
Reactome Imported
    Subnetwork: Cell death signalling via NRAGE, NRIF and NADE
Reactome Imported
    Subnetwork: Ceramide signalling
Reactome Imported
    Subnetwork: ERK activation
Reactome Imported
    Subnetwork: ERK/MAPK targets
Reactome Imported
    Subnetwork: ERK1 activation
Reactome Imported
    Subnetwork: ERK2 activation
Reactome Imported
    Subnetwork: ERKs are inactivated
Reactome Imported
    Subnetwork: Frs2-mediated activation
Reactome Imported
    Subnetwork: MAP kinase cascade
Reactome Imported
    Subnetwork: MEK activation
Reactome Imported
    Subnetwork: NADE modulates death signalling
Reactome Imported
    Subnetwork: NF-kB is activated and signals survival
Reactome Imported
    Subnetwork: NFG and proNGF binds to p75NTR
Reactome Imported
    Subnetwork: NGF processing
Reactome Imported
    Subnetwork: NGF-independant TRKA activation
Reactome Imported
    Subnetwork: NRAGE signals death through JNK
Reactome Imported
    Subnetwork: NRIF signals cell death from the nucleus
Reactome Imported
    Subnetwork: Negative regulation of the PI3K/AKT network
Reactome Imported
    Subnetwork: Nuclear Events (kinase and transcription factor activation)
Reactome Imported
    Subnetwork: PI3K/AKT signalling
Reactome Imported
    Subnetwork: PLC-gamma1 signalling
Reactome Imported
    Subnetwork: Prolonged ERK activation events
Reactome Imported
    Subnetwork: RAF activation
Reactome Imported
    Subnetwork: RAF phosphorylates MEK
Reactome Imported
    Subnetwork: Regulated proteolysis of p75NTR
Reactome Imported
    Subnetwork: Retrograde neurotrophin signalling
Reactome Imported
    Subnetwork: Signalling to ERK5
Reactome Imported
    Subnetwork: Signalling to ERKs
Reactome Imported
    Subnetwork: Signalling to RAS
Reactome Imported
    Subnetwork: Signalling to STAT3
Reactome Imported
    Subnetwork: Signalling to p38 via RIT and RIN
Reactome Imported
    Subnetwork: TRKA activation by NGF
Reactome Imported
    Subnetwork: TRKA signalling from the plasma membrane
Reactome Imported
    Subnetwork: p38MAPK events
Reactome Imported
    Subnetwork: p75 NTR receptor-mediated signalling
Reactome Imported
    Subnetwork: p75NTR negatively regulates cell cycle via SC1
Reactome Imported
    Subnetwork: p75NTR recruits signalling complexes
Reactome Imported
    Subnetwork: p75NTR regulates axonogenesis
Reactome Imported
    Subnetwork: p75NTR signals via NF-kB
Reactome Imported
Synaptic Transmission Reactome Imported
    Subnetwork: Astrocytic Glutamate-Glutamine Uptake And Metabolism
Reactome Imported
    Subnetwork: Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Reactome Imported
    Subnetwork: Glutamate Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Neurotransmitter Clearance In The Synaptic Cleft
Reactome Imported
    Subnetwork: Neurotransmitter Release Cycle
Reactome Imported
    Subnetwork: Neurotransmitter uptake and Metabolism In Glial Cells
Reactome Imported
    Subnetwork: Transmission across Chemical Synapses
Reactome Imported
Synthesis of lysophosphatidic acid from dihydroxyacetone phosphate Reactome Imported
Tat-mediated HIV-1 elongation arrest and recovery Reactome Imported
Telomere Maintenance Reactome Imported
    Subnetwork: Extension of Telomeres
Reactome Imported
    Subnetwork: Packaging Of Telomere Ends
Reactome Imported
    Subnetwork: Polymerase switching on the C-strand of the telomere
Reactome Imported
    Subnetwork: Processive synthesis on the C-strand of the telomere
Reactome Imported
    Subnetwork: Removal of the Flap Intermediate from the C-strand
Reactome Imported
    Subnetwork: Telomere C-strand (Lagging Strand) Synthesis
Reactome Imported
    Subnetwork: Telomere C-strand synthesis initiation
Reactome Imported
    Subnetwork: Telomere Extension By Telomerase
Reactome Imported
Transcription Reactome Imported
    Subnetwork: Cleavage of Growing Transcript in the Termination Region
Reactome Imported
    Subnetwork: Formation of RNA Pol II elongation complex
Reactome Imported
    Subnetwork: Formation of the Early Elongation Complex
Reactome Imported
    Subnetwork: Mitochondrial transcription initiation
Reactome Imported
    Subnetwork: Mitochondrial transcription termination
Reactome Imported
    Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE
Reactome Imported
    Subnetwork: RNA Polymerase I Chain Elongation
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Clearance
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase I Promoter Opening
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase I Transcription Termination
Reactome Imported
    Subnetwork: RNA Polymerase II Promoter Escape
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Elongation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Pre-Initiation
Reactome Imported
    Subnetwork: RNA Polymerase II Transcription Termination
Reactome Imported
    Subnetwork: RNA Polymerase III Chain Elongation
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 1 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 2 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Initiation From Type 3 Promoter
Reactome Imported
    Subnetwork: RNA Polymerase III Transcription Termination
Reactome Imported
    Subnetwork: Transcription from mitochondrial promoters
Reactome Imported
Vitamin D (calciferol) metabolism Reactome Imported
mRNA Processing Reactome Imported
    Subnetwork: C6 deamination of adenosine
Reactome Imported
    Subnetwork: Formation of editosomes by ADAR proteins
Reactome Imported
    Subnetwork: Formation of the Editosome
Reactome Imported
    Subnetwork: Processing of Capped Intron-Containing Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped Intronless Pre-mRNA
Reactome Imported
    Subnetwork: Processing of Capped pre-mRNA
Reactome Imported
    Subnetwork: Processing of Intronless Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Reactome Imported
    Subnetwork: SLBP independent Processing of Histone Pre-mRNAs
Reactome Imported
    Subnetwork: Transport of Mature Transcript to Cytoplasm
Reactome Imported
    Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript
Reactome Imported
    Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts
Reactome Imported
    Subnetwork: Transport of the SLBP Dependant Mature mRNA
Reactome Imported
    Subnetwork: Transport of the SLBP independent Mature mRNA
Reactome Imported
    Subnetwork: mRNA 3'-end processing
Reactome Imported
    Subnetwork: mRNA Capping
Reactome Imported
    Subnetwork: mRNA Editing
Reactome Imported
    Subnetwork: mRNA Editing: A to I Conversion
Reactome Imported
    Subnetwork: mRNA Editing: C to U Conversion
Reactome Imported
    Subnetwork: mRNA Splicing
Reactome Imported
    Subnetwork: mRNA Splicing - Major Pathway
Reactome Imported
    Subnetwork: mRNA Splicing - Minor Pathway
Reactome Imported

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