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Volume 2: No. 2, April 2005
TOOLS AND TECHNIQUES
The Asthma Consultative Process: A Collaborative Approach to Integrating Genomics
Into Public Health Practice
This flowchart illustrates how scientific findings are translated into
public health practice. The chart flows from left (starting with “Genetic
Contribution of Disease”) to right (ending with “Improved Health Outcomes”).
An arrow along the top of the chart indicates this left to right progression.
In addition, two arrows positioned head to tail in a circle along the bottom
of the chart indicate that the five major components of the pathway interact
with each other.
| Identification of Genetic Component |
Family history studies |
Gene discovery |
Gene function |
Gene–disease associations |
| Characteristics of Risk |
Gene–gene |
Gene–environment |
Biologic pathways |
Multicausal pathways |
| Intervention Design |
Clinical trials |
Clinical management |
Environmental change |
Drug development |
| Implementation & Assessment |
Education |
Behavioral change |
Systems change |
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| Public & Private Policy |
Assessment of health care delivery |
Evaluation of harms/benefits of genetic information |
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Figure 1. Translational pathway, which serves to
illustrate translation of scientific findings into public health practice.
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