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Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever Home > Glossary

Glossary

glucose-6-phosphate dehydrogenase: an enzyme involved in maintaining the membrane integrity of red blood cells.  Deficiency of this enzyme is a sex-linked genetic condition which occurs with highest frequencies in people of African, Middle Eastern and Southeast Asian origin; it affects 12% of the U.S. African-American male population.  Some drugs and infections can cause red blood cells to burst, resulting in severe anemia and other complications among persons deficient in this enzyme.

histology: the branch of anatomy that deals with the structure, composition, and function of body tissues.

hyponatremia: low sodium level in the blood

immunostaining: the laboratory process of detecting an organism in tissues with antibodies. These antibodies are labeled with a fluorescent compound that is seen as a colored deposit when viewed with a light microscope.

indirect immunofluorescence assay (IFA): a laboratory test used to detect antibodies to an organism in serum or other body fluid. The specific antibodies are labeled with a compound that glows when observed microscopically under ultraviolet light.

polymerase chain reaction (PCR): a method used to make multiple copies of DNA by a process developed in the mid-1980s. It is used to detect the existence of specific microbial genes in DNA samples extracted from infected blood, tissue or ticks.

serology: the branch of science dealing with the measurement and characterization of antibodies and other immunological substances in body fluids, particularly serum.

thrombocytopenia: low platelet count

 

 

Date last reviewed: 05/20/2005

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Tick-Borne Rickettsial Disease Case Report. Use for reporting cases of RMS, HME, and HGE.
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