Eblin, Kylee E., Tiffany G. Bredfeldt, and A. Jay Gandolfi. 2008. Immortalized human urothelial cells as a model of arsenic-induced bladder cancer. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) doi:10.1016/j.tox.2008.03.020(http://dx.doi.org/10.1016/j.tox.2008.03.020) 248(2-3):67-76.
Eblin, Kylee E., A.M. Hau, T.J. Jensen, B.W. Futscher, and A. Jay Gandolfi. 2008. The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) doi:10.1016/j.tox.2008.05.018(http://dx.doi.org/10.1016/j.tox.2008.05.018) 250(1):47-54.
Meza, Maria Mercedes, Michael J. Kopplin, Jefferey L. Burgess, and A. Jay Gandolfi. 2008. Urinary arsenic profile in children and adults exposed to low levels through drinking water in Sonora, Mexico. Journal of Toxicology and Environmental Health, Part A. (http://www.tandf.co.uk/journals/titles/152873 94.asp) (in press)
2007
Eblin, Kylee E., Tiffany G. Bredfeldt, Sarah Buffington, and A. Jay Gandolfi. 2007. Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 95(2):321-30.
Eblin, Kylee E., Tiffany G. Bredfeldt, Sarah Buffington, and A. Jay Gandolfi. 2007. Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 95(2):321-330.
Meza, Maria Mercedes, A. Jay Gandolfi, and Walter T. Klimecki. 2007. Developmental and genetic modulation of arsenic biotransformation: a gene by environment interaction?. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 222(3):381-7.
Wang, X., Z. Sun, W. Chen, Kylee E. Eblin, A. Jay Gandolfi, and D. Zhang. 2007. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 225(2):206-13.
2006
Bredfeldt, Tiffany G., Bhumasamudram Jagadish, Kylee E. Eblin, Eugene A. Mash, and A. Jay Gandolfi. 2006. Monomethylarsonous acid induces transformation of human bladder cells. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 216(1):69-79.
Eblin, Kylee E., Martina E. Bowen, Douglas W. Cromey, Tiffany G. Bredfeldt, Eugene A. Mash, Serrine S. Lau, and A. Jay Gandolfi. 2006. Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 217(1):7-14.
Peraza, Marjorie A., Douglas W. Cromey, Barb Carolus, Dean E. Carter, and A. Jay Gandolfi. 2006. Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: evidence for targeting of mitochondria and initiated apoptosis. Journal of Applied Toxicology. 26(4):356-67.
2005
Billings, K.E., Tiffany G. Bredfeldt, Xing Hui Zheng, Michael J. Kopplin, George S. Watts, D.A. Sens, Eugene A. Mash, and A. Jay Gandolfi. 2005. Characterization of Human Bladder Urothelial Cells Malignantly Transformed by Arsenite. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 84(S1):31.
Bredfeldt, Tiffany G., K.E. Billings, Xing Hui Zheng, Eugene A. Mash, F.E. Domann, Serrine S. Lau, D.A. Sens, and A. Jay Gandolfi. 2005. Arsenite and Monomethyl Arsonous Acid-Induced Toxicity ion Human Urothelial Cells. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 84(S1):31.
Kirkpatrick, Donald S., Stephen F. Weldon, George Tsaprailis, Daniel C. Liebler, and A. Jay Gandolfi. 2005. Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin. Proteomics. 5(8):2104-2111.
Meza, Maria Mercedes, Lizhi Yu, Yelitza Y. Rodriguez, Mischa Guild, David Thompson, A. Jay Gandolfi, and Walter T. Klimecki. 2005. Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children. Environmental Health Perspectives. 113(6):775-781.
Sierra-Alvarez, Reyes, James A. Field, Irail Cortinas, Gumersindo Feijoo, Maria Teresa Moreira, Michael J. Kopplin, and A. Jay Gandolfi. 2005. Anaerobic Microbial Mobilization and Biotransformation of Arsenate Adsorbed onto Activated Alumina. Water Research. (http://www.elsevier.com/inca/publications/sto re/3/0/9/index.htt) 39(1):199-209.
Zheng, Xing Hui, Tiffany G. Bredfeldt, George S. Watts, and A. Jay Gandolfi. 2005. Toxicogenomical Study on Human Bladder Epithelium Exposed to Arsenic. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 84(S1):238.
2004
Bredfeldt, Tiffany G., Michael J. Kopplin, and A. Jay Gandolfi. 2004. Effects of arsenite on UROtsa cells: low-level arsenite causes accumulation of ubiquitinated proteins that is enhanced by reduction in cellular glutathione levels. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 198(3):412-418.
Field, James A., Reyes Sierra-Alvarez, Irail Cortinas, Gumersindo Feijoo, Maria Teresa Moreira, Michael J. Kopplin, and A. Jay Gandolfi. 2004. Facile Reduction of Arsenate in Methanogenic Sludge. Biodegradation. (http://www.springerlink.com/content/1572-9729 /) 15(3):185-196.
Meza, Maria Mercedes, Michael J. Kopplin, Jefferey L. Burgess, and A. Jay Gandolfi. 2004. Arsenic drinking water exposure and urinary excretion among adults in the Yaqui Valley, Sonora, Mexico. Environmental Research. (http://www.elsevier.com/locate/issn/0013-9351) 96(2):119-126.
Nyman, David W., M. Suzanne Stratton, Michael J. Kopplin, Bruce L. Dalkin, Raymond B. Nagle, and A. Jay Gandolfi. 2004. Selenium and selenomethionine levels in prostate cancer patients. Cancer Detection and Prevention. 28(1):8-16.
2003
Carter, Dean E., H. Vasken Aposhian, and A. Jay Gandolfi. 2003. The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 193(3):309-334.
A. Jay Gandolfi. 2003. In vitro techniques in screening and mechanistic studies: organ perfusion, slices, and nephron components. In: Toxicology and the Kidney - Third Edition.
Kirkpatrick, Donald S., K.V. Dale, Jeffery M. Catania, and A. Jay Gandolfi. 2003. Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK 293 cells. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 186(2):101-109.
Kirkpatrick, Donald S., Stephen F. Weldon, George Tsaprailis, Daniel C. Liebler, and A. Jay Gandolfi. 2003. Qualitative and quantitative analysis of changes in the ubiquitin pathway in human cells using LC-MS/MS. Molecular and Cellular Proteomics.
Peraza, Marjorie A., Dean E. Carter, and A. Jay Gandolfi. 2003. Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2). Cell Biology and Toxicology. 19(4):253-264.
Quanrud, David M., Robert G. Arnold, Kevin E. Lansey, Carmen K. Begay, Wendell P. Ela, and A. Jay Gandolfi. 2003. Fate of effluent organic matter during soil aquifer treatment: biodegradability, chlorine reactivity and genotoxicity. Journal of Water Health. 1(1):33-44.
Sierra-Alvarez, Reyes, James A. Field, Irail Cortinas, Michael J. Kopplin, and A. Jay Gandolfi. 2003. Microbial reduction and mobilization of arsenate under landfill conditions. In: Proceedings of the 7th International Symposium on In Situ and On-Site Bioremediation. Orlando, FL.
Yenal, Umur, James A. Field, Reyes Sierra-Alvarez, Michael J. Kopplin, Carmen K. Begay, and A. Jay Gandolfi. 2003. Anaerobic biodegradation of organoarsenical pesticides, methyarsonic acid (MMAV) and dimethylarsinic acid (DMAV). In: Proceedings of the Southwest Environmental Health Sciences Center(SWEHSC)/Superfund Science Fair, May 20, 2003. Tucson, AZ.
Zheng, Xing Hui, George S. Watts, Skip Vaught, and A. Jay Gandolfi. 2003. Low-level arsenate induced gene expression in HEK 293 cells. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) 187(1):39-48.
2002
K.V. Dale, Daniel C. Liebler, and A. Jay Gandolfi. 2002. Identification of ubiquitin-conjugated proteins using lc-ms techniques: potential molecular indicators of toxic insults. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 66:A1083.
Peraza, Marjorie A., Michael J. Kopplin, Dean E. Carter, and A. Jay Gandolfi. 2002. Inorganic arsenic biotransformation and mitochondrial toxicity in HK-2 human proximal tubular cells. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 66:A403.
Sipes, I.G., C.A. McQueen, and A. Jay Gandolfi. 2002. Inorganic arsenic biotransformation and mitochondrial toxicity in HK-2 human proximal tubular cells. In: Comprehensive Toxicology. Vol. 14, Cellular and Molecular Toxicology. Elsevier-Academic Press, pp.644.
2001
K.V. Dale, Daniel C. Liebler, and A. Jay Gandolfi. 2001. Identification of ubiquitin-conjugated proteins using lc-ms techniques: potential molecular indicators of toxic insults. In: Proceedings of the Symposium on Gene Expression, December 2-4. Bethesda, MD.
Gandolfi, A.Jay. 2001. Hazardous Waste Risk and Remediation in the Southwest. In: Proceedings of the Superfund Basic Research Program Annual Meeting: Assessing Risks of Hormonally Active Agents, December 10-12, 2001. University of Florida Conference Center, Gainsville, FL.
A. Jay Gandolfi. 2001. Organ Perfusion, Slices and Nephron Components in Toxicology of the Kidney. In: In Vitro Techniques in Screening and Mechanistic Studies (3rd edition). Raven Press,
Wijeweera, Jayanthika B., A. Jay Gandolfi, Alan R. Parrish, and Robert Clark Lantz. 2001. Sodium arsenite enhances AP-1 and NFKB DNA binding and induces stress protein expression in precision-cut rat lung slices. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 61(2):283-294.
2000
Jeffery M. Catania and A. Jay Gandolfi. 2000. Increased ubiquitin-conjugated proteins following low-level arsenite exposure. In: Proceedings of the SEGH (Society for Environmental Geochemistry and Health) Fourth International Conference on Arsenic Exposure and Health Effects, June 18-22. San Diego, CA.
Zheng, Xing Hui, A. Jay Gandolfi, C.L. Wilson, and Alan R. Parrish. 2000. Analysis of differential expressed genes in rabbit renal cortical slices exposed to arsenic compounds. In: Proceedings of the SEGH (Society for Environmental Geochemistry and Health) Fourth International Conference on Arsenic Exposure and Health Effects, June 18-22. San Diego, CA.
Zheng, Xing Hui, Alan R. Parrish, and A. Jay Gandolfi. 2000. Analysis of differentially-expressed genes in rabbit renal cortical slices exposed to arsenic compounds. Southwest Environmental Health Sciences Newsletter, Winter 99/00.
Zheng, Xing Hui, C.L. Wilson, Alan R. Parrish, and A. Jay Gandolfi. 2000. Differential gene expression in rabbit renal cortical slices exposed to arsenic compounds. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 54:
1999
Keith, Rodney L., A. Jay Gandolfi, L.C. McIntyre, Jr., M.D. Ashbaugh, and Quintus Fernando. 1999. Analysis of heavy metal deposition in biological tissue by sectional mapping using m-PIXE. Nuclear Instruments and Methods. (http://www.sciencedirect.com/science/journal/ 01689002) 149:167-176.
Parrish, Alan R., Xing Hui Zheng, Karen D. Turney, Husam S. Younis, and A. Jay Gandolfi. 1999. Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 50:98-105.
Turney, Karen D., Alan R. Parrish, and A. Jay Gandolfi. 1999. Selective activation in the MAPK pathway by Hg(II). Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 48:331.
Turney, Karen D., Alan R. Parrish, Jason Orozco, and A. Jay Gandolfi. 1999. Selective activation in the MAPK pathway by Hg(II) in precision-cut rabbit renal cortical slices. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 160(3):262-270.
Wei, H., L. Qiu, Kevin K. Divine, M.D. Ashbaugh, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1999. Toxicity and transport of three synthesized mercury-thiol-complexes in isolated rabbit renal proximal tubule suspensions. Drug and Chemical Toxicology. (http://www.informaworld.com/smpp/title~conten t=t713597244) 22(2):323-341.
Zheng, Xing Hui, Alan R. Parrish, Karen D. Turney, Husam S. Younis, and A. Jay Gandolfi. 1999. Arsenite [AS(III)] and arsenate [AS(V)] enhance DNA binding of the AP-1 and elk-1 transcription factors and c-jun and c-fos gene expression in precision-cut renal slices. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 48:351.
1998
Gandolfi, A.Jay, Alan R. Parrish, Karen D. Turney, and Xing Hui Zheng. 1998. Molecular alteration in renal tissue following in vitro exposure to nanomolar levels of Hg(II), As(III) or As(V). In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA.
Keith, Rodney L., L.C. McIntyre, Jr., M.D. Ashbaugh, Quintus Fernando, and A. Jay Gandolfi. 1998. Characterization of heavy metal deposition in rabbit renal tissue using micro-proton induced x-ray emission. In: Proceedings Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
Parrish, Alan R., Robyn L. Fisher, C.M. Bral, Robert C. Burghardt, A. Jay Gandolfi, Klaus Brendel, and Kenneth S. Ramos. 1998. Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver slices. Toxicology and Applied Pharmacology. (http://www.academicpress.com/tap) 152:302-308.
Qiu, L., J.R. Lott, Quintus Fernando, M.D. Ashbaugh, L.C. McIntyre, Jr., Rodney L. Keith, H. Wei, and A. Jay Gandolfi. 1998. The PIXE and micro-PIXE facility at the University of Arizona. In: Proceedings Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
Turney, Karen D., Alan R. Parrish, and A. Jay Gandolfi. 1998. Changes in AP-1 and c-jun expression in precision-cut rabbit renal cortical slices following exposure to Hg(II). The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 31:380.
Turney, Karen D., Alan R. Parrish, and A. Jay Gandolfi. 1998. Increased AP-1 and c-jun in renal slices following exposure to Hg(II). In: Proceedings of the Symposium on Risk Considerations for Environmental Health and Safety. The University of Arizona, Tucson, AZ.
Wei, H., L. Qiu, Kevin K. Divine, M.D. Ashbaugh, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1998. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. In: Proceedings Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
Wijeweera, Jayanthika B., A. Jay Gandolfi, and Xing Hui Zheng. 1998. Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut liver slices. Environmental Health Perspectives. 106(Suppl.6):1319-1323.
Zheng, Xing Hui, Husam S. Younis, Karen D. Turney, Alan R. Parrish, and A. Jay Gandolfi. 1998. Molecular alterations in renal cortical slices following exposure to sub-toxic levels of arsenic. Toxicological Sciences. (http://www3.oup.co.uk/toxsci/) 42:323.
Zheng, Xing Hui, Husam S. Younis, Karen D. Turney, Alan R. Parrish, and A. Jay Gandolfi. 1998. Molecular alterations in renal slices following arsenite exposure. In: Proceedings of the Symposium on Risk Considerations for Environmental Health and Safety. The University of Arizona, Tucson, AZ.
1997
Keith, Rodney L., A. Jay Gandolfi, L.C. McIntyre, Jr., M.D. Ashbaugh, and Quintus Fernando. 1997. Use of the nuclear microprobe at the University of Arizona for the study of heavy metal deposition in rabbit renal tissue. Nuclear Instruments and Methods. (http://www.sciencedirect.com/science/journal/ 01689002) 130:358-361.
Keith, Rodney L., L.C. McIntyre, Jr., M.D. Ashbaugh, Quintus Fernando, and A. Jay Gandolfi. 1997. Characterization of heavy metal deposition in rabbit renal tissue using micro-proton induced x-ray emission. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 36:185.
Keith, Rodney L., I. Setiarahardjo, Quintus Fernando, H. Vasken Aposhian, and A. Jay Gandolfi. 1997. Utilization of renal slices to evaluate the efficacy of chelators to remove mercury from the kidney. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) 116:67-75.
McIntyre, Jr., L.C., J.A. Leavitt, M.D. Ashbaugh, J. Borgardt, Rodney L. Keith, A. Jay Gandolfi, L. Qiu, J.R. Lott, and Quintus Fernando. 1997. The nuclear microprobe at the University of Arizona. Nuclear Instruments and Methods. (http://www.sciencedirect.com/science/journal/ 01689002) 130:45-50.
Wei, H., L. Qiu, Kevin K. Divine, M.D. Ashbaugh, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1997. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. In: Proceedings of the TCE Symposium, The University of Arizona, Tucson, AZ.
Wei, H., L. Qiu, Kevin K. Divine, M.D. Ashbaugh, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1997. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 36:185.
Wijeweera, Jayanthika B., Xing Hui Zheng, and A. Jay Gandolfi. 1997. Interactive toxicity of MCA and VDC in precision-cut rat livers slices. In: Proceedings of the Current Issues in Chemical Mixtures Conference. Colorado State University, Ft. Collins, CO.
1996
Gandolfi, A.Jay, Klaus Brendel, and Quintus Fernando. 1996. Preparation and use of precision-cut renal cortical slices in renal toxicology. In: Methods of Renal Toxicology. CRC Press, Inc., Boca Raton, FL. pp.109-122.
Keith, Rodney L., A. Jay Gandolfi, L.C. McIntyre, Jr., M.D. Ashbaugh, L. Qiu, J.R. Lott, and Quintus Fernando. 1996. Use of the nuclear microprobe at the University of Arizona for the study of heavy metal deposition in rabbit renal tissue. In: Proceedings of the International Conference on Nuclear Microprobe Technology and Applications. Sante Fe, NM.
Keith, Rodney L., J.A. Leavitt, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1996. Assessment of heavy metal accumulation in renal tissue using micro-proton induced x-ray emission (m-PIXE). The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 30:258.
Wei, H., Kevin K. Divine, and A. Jay Gandolfi. 1996. Uptake and toxicity of HgCl2 and synthesized Hg(SG)2 and Hg(CYS)2 in isolated rabbit renal proximal tubule suspensions. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 30:129.
1995
Burton, Carmen A., Kristina Hatlelid, Kevin K. Divine, Dean E. Carter, Quintus Fernando, Klaus Brendel, and A. Jay Gandolfi. 1995. Glutathione effects on toxicity and uptake of mercuric chloride and sodium arsenite in rabbit renal cortical slices. Environmental Health Perspectives. 103(Suppl.1):81-84.
Gandolfi, A.Jay, Klaus Brendel, Robyn L. Fisher, and John-Pierre Michaud. 1995. Use of tissue slices in chemical mixture toxicology and interspecies investigations. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) 105(2-3):285-290.
Hasal, S.J., H. Vasken Aposhian, A. Jay Gandolfi, and Klaus Brendel. 1995. Human and rabbit renal cortical slices in aerated submersion culture as a model to evaluate heavy metal chelators. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 15:310.
Keith, Rodney L., J.A. Leavitt, L.C. McIntyre, Jr., Quintus Fernando, and A. Jay Gandolfi. 1995. Use of micro-proton induced x-ray emission (μ-PIXE) for heavy metal analysis. The Toxicologist. (http://www.toxicology.org/ai/pub/journals.asp #toxicologist) 15:106.
Keith, Rodney L., Sharon J. McGuinness, A. Jay Gandolfi, Timothy P. Lowe, Quan Chen, and Quintus Fernando. 1995. Interaction of metals during their uptake and accumulation in rabbit renal cortical slices. Environmental Health Perspectives. 103(Suppl.1):77-80.
Wijeweera, Jayanthika B., C.M. Thomas, A. Jay Gandolfi, and Klaus Brendel. 1995. Sodium arsenite and heat shock induce stress proteins in precision-cut liver slices. Toxicology. (http://www.sciencedirect.com/science/journal/ 0300483X) 104:35-45.
1993
Lowe, Timothy P., Quan Chen, Quintus Fernando, Rodney L. Keith, and A. Jay Gandolfi. 1993. Elemental Analysis of Renal Slices by Proton-Induced X-Ray Emission. Environmental Health Perspectives. 101:302.
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